IE811069L - Esters of substituted benzoic acid - Google Patents

Esters of substituted benzoic acid

Info

Publication number
IE811069L
IE811069L IE811069A IE106981A IE811069L IE 811069 L IE811069 L IE 811069L IE 811069 A IE811069 A IE 811069A IE 106981 A IE106981 A IE 106981A IE 811069 L IE811069 L IE 811069L
Authority
IE
Ireland
Prior art keywords
esters
benzoic acid
substituted benzoic
formula
image
Prior art date
Application number
IE811069A
Other versions
IE51324B1 (en
Original Assignee
Bago Sa Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE2/58723A external-priority patent/BE884978A/en
Application filed by Bago Sa Labor filed Critical Bago Sa Labor
Publication of IE811069L publication Critical patent/IE811069L/en
Publication of IE51324B1 publication Critical patent/IE51324B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)

Abstract

Derivatives of 2-hydroxybenzoic acid have the formula (I> <IMAGE> wherein R1 represents a hydroxy or C2-5 acyloxy group; R2 represents a radical of the formula (II> <IMAGE> in which R4 and R5 each represent a hydrogen atom or together form an aromatic ring fused to the heterocyclic ring and R3 represents a hydrogen or halogen atom, the compounds have a greater analgesic and anti-inflammatory activity than 2-hydroxybenzoic acid without the irritation of the gastric mucosa which has been given by the other derivatives previously known in the art. [GB2086881A]
IE1069/81A 1980-08-29 1981-05-03 Esters of substituted benzoic acid IE51324B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE2/58723A BE884978A (en) 1980-08-29 1980-08-29 NEW ESTERS OF SUBSTITUTED BENZOIC ACID

Publications (2)

Publication Number Publication Date
IE811069L true IE811069L (en) 1982-02-28
IE51324B1 IE51324B1 (en) 1986-12-10

Family

ID=3865514

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1069/81A IE51324B1 (en) 1980-08-29 1981-05-03 Esters of substituted benzoic acid

Country Status (6)

Country Link
JP (1) JPS5742680A (en)
DE (1) DE3105908A1 (en)
FR (1) FR2489328B1 (en)
GB (1) GB2086881B (en)
IE (1) IE51324B1 (en)
IT (1) IT1167704B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5861518A (en) * 1994-11-21 1999-01-19 Dekker; Koenraad A. Phthalide compounds and their production process

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2877236A (en) * 1956-08-03 1959-03-10 Dow Chemical Co Phthalidyl esters of aromatic acids
GB1463767A (en) * 1973-03-19 1977-02-09 Konishiroku Photo Ind Gelating hardening process
NL7510622A (en) * 1974-09-17 1976-03-19 Rhone Poulenc Ind PROCESS FOR THE PREPARATION OF MEDICINAL PRODUCTS HAVING INCLUDED AN ANTI-INFLAMMATORY, ANALGETIC AND ANTI-PYROLYTIC ACTION, THE PREPARED MEDICINAL PRODUCTS AND A PROCESS FOR THE PREPARATION OF THE FINDED ACYLOGEN TREASURIES.
FR2300571A1 (en) * 1975-02-12 1976-09-10 Union Pharma Scient Appl Stable, water soluble acetylsalicyclic acid addition salts - with 2-amino 2-methyl propanol or corresp. 1,3-propanediol
US4029810A (en) * 1976-01-02 1977-06-14 American Home Products Corporation Lactone esters of phenoxyisobutyric acids
US4046887A (en) * 1976-10-28 1977-09-06 Abbott Laboratories Glycerides with anti-inflammatory properties
BE858864A (en) * 1977-09-20 1978-01-16 Bago Sa Labor NEW ESTERS OF PHENYL- AND PYRIDINE-3-CARBOXYLIC ACIDS AND PROCESS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
FR2489328B1 (en) 1985-09-20
IT1167704B (en) 1987-05-13
GB2086881B (en) 1984-07-18
DE3105908C2 (en) 1990-05-31
FR2489328A1 (en) 1982-03-05
JPS5742680A (en) 1982-03-10
IT8119478A1 (en) 1982-08-03
IE51324B1 (en) 1986-12-10
GB2086881A (en) 1982-05-19
IT8119478A0 (en) 1981-02-03
DE3105908A1 (en) 1982-04-15

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