ATE142623T1 - 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln - Google Patents

2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Info

Publication number
ATE142623T1
ATE142623T1 AT92102156T AT92102156T ATE142623T1 AT E142623 T1 ATE142623 T1 AT E142623T1 AT 92102156 T AT92102156 T AT 92102156T AT 92102156 T AT92102156 T AT 92102156T AT E142623 T1 ATE142623 T1 AT E142623T1
Authority
AT
Austria
Prior art keywords
substituted
substituted quinolines
production
medicinal products
quinolines
Prior art date
Application number
AT92102156T
Other languages
German (de)
English (en)
Inventor
Siegfried Dr Raddatz
Klaus-Helmut Dr Mohrs
Michael Dr Matzke
Romanis Fruchtmann
Armin Dr Hatzelmann
Christian Dr Kohlsdorfer
Reiner Pro Mueller-Peddinghaus
Pia Dr Theisen-Popp
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE142623T1 publication Critical patent/ATE142623T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Earth Drilling (AREA)
AT92102156T 1991-02-22 1992-02-10 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln ATE142623T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4105551A DE4105551A1 (de) 1991-02-22 1991-02-22 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ATE142623T1 true ATE142623T1 (de) 1996-09-15

Family

ID=6425643

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92102156T ATE142623T1 (de) 1991-02-22 1992-02-10 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Country Status (20)

Country Link
EP (1) EP0499926B1 (enExample)
JP (1) JPH0592957A (enExample)
KR (1) KR920016424A (enExample)
AT (1) ATE142623T1 (enExample)
AU (1) AU641585B2 (enExample)
CZ (1) CZ282723B6 (enExample)
DE (2) DE4105551A1 (enExample)
DK (1) DK0499926T3 (enExample)
ES (1) ES2091958T3 (enExample)
FI (1) FI920732A7 (enExample)
GR (1) GR3021014T3 (enExample)
HU (1) HUT67037A (enExample)
IE (1) IE75728B1 (enExample)
IL (1) IL101009A (enExample)
MY (1) MY108459A (enExample)
NZ (1) NZ241654A (enExample)
PL (2) PL171026B1 (enExample)
RU (1) RU2077532C1 (enExample)
TW (1) TW200463B (enExample)
ZA (1) ZA921268B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4226649A1 (de) * 1992-08-12 1994-02-17 Bayer Ag Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole
US5304563A (en) * 1991-02-22 1994-04-19 Bayer Aktiengesellschaft 2-substituted quinolines, and their use in medicaments
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
US5391555A (en) * 1991-11-12 1995-02-21 Miles Inc. Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors
TW232013B (enExample) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
DE4219765A1 (de) * 1992-06-17 1993-12-23 Bayer Ag Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
DE69422450T2 (de) * 1993-06-29 2000-06-08 Takeda Chemical Industries, Ltd. Chinoline oder Chinazolin-Derivate und deren Verwendung zur Herstellung eines Medikaments für die Behandlung von Osteoporose
DE4443891A1 (de) 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
AR029876A1 (es) * 1998-05-11 2003-07-23 Takeda Pharmaceutical Compuesto de acido oxiiminoalcanoilo, composicion farmaceutica y agente para controlar receptores relacionados con retinoide que lo comprenden y su uso
GB9818641D0 (en) * 1998-08-26 1998-10-21 Rh Ne Poulenc Rorer Limited Chemical compounds
CN101070316A (zh) * 1999-04-28 2007-11-14 萨诺费－阿文蒂斯德国有限公司 作为ppar受体配体的二芳基酸衍生物
RU2177317C1 (ru) * 2000-10-24 2001-12-27 Московский научно-исследовательский институт медицинской экологии (МНИИМЭ) Производные хинолина для коррекции системы гемостаза, фармацевтическая композиция, средство для коррекции гемостаза
TWI309644B (enExample) * 2001-02-14 2009-05-11 Nissan Chemical Ind Ltd
US6867320B2 (en) 2002-02-21 2005-03-15 Asahi Kasei Pharma Corporation Substituted phenylalkanoic acid derivatives and use thereof
SV2005001973A (es) 2003-12-12 2005-11-04 Wyeth Corp Quinolinas utiles en el tratamiento de enfermedades cardiovasculares ref. wyth0090-504 (am101500)
RU2391338C2 (ru) * 2004-10-19 2010-06-10 Ф.Хоффманн-Ля Рош Аг Производные хинолина
ES2360014T3 (es) * 2006-12-21 2011-05-31 Pfizer Products Inc. Sal succinato de 2-((4-(1-metil-4-(piridin-4-il)-1h-pirazol-3-il)-fenoxi)metil)quinolina.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3900261A1 (de) * 1988-05-31 1989-12-07 Bayer Ag Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
DE3908298A1 (de) * 1989-03-14 1990-09-20 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-n,n'-sulfonylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3916663A1 (de) * 1989-05-23 1990-11-29 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate
DE3927930A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate

Also Published As

Publication number Publication date
AU641585B2 (en) 1993-09-23
FI920732L (fi) 1992-08-23
RU2077532C1 (ru) 1997-04-20
CS51492A3 (en) 1992-12-16
IE75728B1 (en) 1997-09-24
KR920016424A (ko) 1992-09-24
TW200463B (enExample) 1993-02-21
DE59207074D1 (de) 1996-10-17
GR3021014T3 (en) 1996-12-31
HUT67037A (en) 1995-01-30
IL101009A0 (en) 1992-11-15
HU9200582D0 (en) 1992-05-28
AU1054292A (en) 1992-08-27
DE4105551A1 (de) 1992-08-27
EP0499926B1 (de) 1996-09-11
PL171026B1 (pl) 1997-02-28
FI920732A0 (fi) 1992-02-20
IL101009A (en) 1996-08-04
FI920732A7 (fi) 1992-08-23
ES2091958T3 (es) 1996-11-16
PL170726B1 (pl) 1997-01-31
PL293534A1 (en) 1992-10-05
CZ282723B6 (cs) 1997-09-17
NZ241654A (en) 1994-11-25
EP0499926A1 (de) 1992-08-26
DK0499926T3 (enExample) 1997-02-10
JPH0592957A (ja) 1993-04-16
ZA921268B (en) 1992-11-25
MY108459A (en) 1996-09-30
IE920557A1 (en) 1992-08-26

Similar Documents

Publication Publication Date Title
ATE142623T1 (de) 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
ATE103267T1 (de) 7-substituierte derivate der 3,5-dihydroxyhept-6- insaeure, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, sowie zwischenprodukte.
EP0302525A3 (en) Quinolones as antibacterial agents
ATE150749T1 (de) Substituierte heterocyclische carbonsäureamide, ihre herstellung und ihre verwendung als arzneimittel
DK543787A (da) Naphthyridin-, quinolin- og benzoxazincarboxylsyreforbindelser med antibakteriel aktivitet
FI892603A0 (fi) Menetelmä uusien, terapeuttisesti käyttökelpoisten 4-(kinolin-2-yylimetoksi)fenyylietikkahappojohdannaisten valmistamiseksi
ATE56433T1 (de) N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung.
DK0612731T3 (da) Nye quinolon- og naphthyridoncarboxylsyrederivater
KR0148213B1 (en) Phenyla lkan(en)oic acid and pharmaceutical composition comprising the same
ATE90676T1 (de) Dioxyalkylenaryl-dihydropyridine zwischenprodukte zu ihrer herstellung, verfahren zu ihrer herstellung und ihre verwendung.
ATE409693T1 (de) Verfahren zur herstellung von 2-(4- chlorbenzoylamino-3- 2(1h)-chinolinon-4-yl propionsäure
ATE38836T1 (de) Substituierte benzopyrane, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln.
ATE53583T1 (de) Beta-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung.
ATE124039T1 (de) Durch azetidine substituierte derivate von pyridon-carboxylsäure, ihre herstellung und verwendung als arzneimittel.
ATE45156T1 (de) Substituierte benzimidazole, verfahren zu ihrer herstellung und ihre anwendung zur hemmung der magensaeuresekretion.
DE3504643A1 (de) 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
ATE139227T1 (de) Acylsulfonamido-und sulfonamidopyridin-2- carbonsäureester sowie ihre pyridin-n-oxide, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel
DE3678470D1 (de) Neue 3-pyridylmethylnaphthylderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE171942T1 (de) 1-piperazinyl-2-butene und 2-butyne, zwischenverbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE28630T1 (de) Substituierte benzolsulfonsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
IE800234L (en) 7-acylindolin-2-ones and 7-acylindolines.
EP0251058A3 (de) Verfahren zur Racemisierung optisch aktiver- Phenoxy- propionsäureester und deren Derivate
ATE77379T1 (de) Neue imidazo- und triazolothiadiazine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte.
IE820118L (en) Anthranilic acid.
ES483463A1 (es) Procedimiento de preparacion de los esteres del 1-metil-4- piperidinol

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee