PL166757B1 - Sposób wytwarzania nowych trójpierscieniowych amin PL PL - Google Patents

Sposób wytwarzania nowych trójpierscieniowych amin PL PL

Info

Publication number
PL166757B1
PL166757B1 PL91288977A PL28897791A PL166757B1 PL 166757 B1 PL166757 B1 PL 166757B1 PL 91288977 A PL91288977 A PL 91288977A PL 28897791 A PL28897791 A PL 28897791A PL 166757 B1 PL166757 B1 PL 166757B1
Authority
PL
Poland
Prior art keywords
ring
formula
group
nitrogen
phenyl
Prior art date
Application number
PL91288977A
Other languages
English (en)
Polish (pl)
Other versions
PL288977A1 (en
Inventor
Yuhpyng L Chen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL288977A1 publication Critical patent/PL288977A1/xx
Publication of PL166757B1 publication Critical patent/PL166757B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL91288977A 1990-02-08 1991-02-06 Sposób wytwarzania nowych trójpierscieniowych amin PL PL PL166757B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47692890A 1990-02-08 1990-02-08

Publications (2)

Publication Number Publication Date
PL288977A1 PL288977A1 (en) 1992-01-13
PL166757B1 true PL166757B1 (pl) 1995-06-30

Family

ID=23893824

Family Applications (2)

Application Number Title Priority Date Filing Date
PL91288977A PL166757B1 (pl) 1990-02-08 1991-02-06 Sposób wytwarzania nowych trójpierscieniowych amin PL PL
PL91304632A PL167078B1 (pl) 1990-02-08 1991-02-06 Sposób wytwarzania nowych trójpierscieniowych pochodnych 4-piperydynylo-indolonulub -imidazolonu PL PL

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL91304632A PL167078B1 (pl) 1990-02-08 1991-02-06 Sposób wytwarzania nowych trójpierscieniowych pochodnych 4-piperydynylo-indolonulub -imidazolonu PL PL

Country Status (21)

Country Link
EP (1) EP0441517A3 (enExample)
JP (1) JPH07119214B2 (enExample)
KR (1) KR950013562B1 (enExample)
CN (1) CN1054600A (enExample)
AU (1) AU631723B2 (enExample)
BR (1) BR9100519A (enExample)
CA (1) CA2035805C (enExample)
CS (1) CS29991A2 (enExample)
DE (1) DE9101348U1 (enExample)
EG (1) EG19644A (enExample)
FI (1) FI910592L (enExample)
HU (1) HUT70051A (enExample)
IE (1) IE910402A1 (enExample)
IL (1) IL97140A (enExample)
NO (1) NO177534C (enExample)
NZ (1) NZ237040A (enExample)
PL (2) PL166757B1 (enExample)
PT (1) PT96681A (enExample)
TW (1) TW197442B (enExample)
YU (1) YU21391A (enExample)
ZA (1) ZA91916B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
EP0475908A1 (de) * 1990-09-14 1992-03-18 Ciba-Geigy Ag Chromogene Lactamverbindungen und ihre Herstellung und Verwendung
TW263504B (enExample) 1991-10-03 1995-11-21 Pfizer
TW248556B (enExample) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
US5620973A (en) * 1993-11-30 1997-04-15 Takeda Chemical Industries, Ltd. Tetracyclic condensed heterocyclic compounds and their use
NZ510685A (en) 1998-09-30 2003-10-31 Takeda Chemical Industries Ltd Drugs for improving vesical excretory strength
BR0315681A (pt) * 2002-10-30 2005-09-06 Merck Frosst Canada Inc Composto e seus sais e hidratos farmaceuticamente aceitáveis, composição farmacêutica, métodos para o tratamento de doenças mediadas pela prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, composto ou um seu sal ou solvato farmaceuticamente aceitável, sal ou hidrato do composto, e, uso de um composto ou de um seu sal ou solvato farmaceuticamente aceitável
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
WO2012038966A1 (en) 2010-09-22 2012-03-29 Tyche Industries Ltd. Process for the preparation of donepezil intermediate
IL272652B (en) * 2017-09-07 2022-09-01 Eisai R&D Man Co Ltd A pentacyclic compound, the pharmaceutical compounds that make it up and their use for the treatment of Alzheimer's disease
MX2021009774A (es) 2019-03-05 2021-09-08 Eisai R&D Man Co Ltd Sal de un compuesto pentaciclico y su cristal.
CN113453762B (zh) 2019-03-05 2024-06-07 卫材R&D管理有限公司 五环杂环化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910947A (en) * 1969-07-24 1975-10-07 Sandoz Ag Preparation of imidazo{8 2,1-a{9 isoindoles
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4563469A (en) * 1984-07-20 1986-01-07 Warner-Lambert Company Derivatives of N-[2-(tetrahydro-3,5-dioxo-1H-pyrrolizin-7a(5H)-yl)ethyl]amine as cognition activators
EP0187619A3 (de) * 1985-01-03 1987-08-26 Ciba-Geigy Ag 1,3-disubstituierte Tetrahydropyridine
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4778812A (en) * 1987-06-12 1988-10-18 American Home Products Corporation 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives thereof
EP0351283A1 (fr) * 1988-07-12 1990-01-17 Synthelabo Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
CN1054600A (zh) 1991-09-18
IE910402A1 (en) 1991-08-14
PL167078B1 (pl) 1995-07-31
NO177534C (no) 1995-10-04
JPH07119214B2 (ja) 1995-12-20
FI910592A0 (fi) 1991-02-07
CS29991A2 (en) 1991-09-15
HUT70051A (en) 1995-09-28
HU910406D0 (en) 1991-08-28
YU21391A (sh) 1994-01-20
NO910473L (no) 1991-08-09
PT96681A (pt) 1991-10-31
CA2035805C (en) 1995-06-27
FI910592A7 (fi) 1991-08-09
IL97140A (en) 1995-07-31
AU631723B2 (en) 1992-12-03
EG19644A (en) 1995-08-30
KR910015580A (ko) 1991-09-30
DE9101348U1 (de) 1991-06-06
KR950013562B1 (ko) 1995-11-09
ZA91916B (en) 1992-09-30
IL97140A0 (en) 1992-05-25
AU7087991A (en) 1991-08-29
NZ237040A (en) 1993-10-26
EP0441517A3 (en) 1992-08-19
JPH04234845A (ja) 1992-08-24
NO177534B (no) 1995-06-26
TW197442B (enExample) 1993-01-01
NO910473D0 (no) 1991-02-07
PL288977A1 (en) 1992-01-13
EP0441517A2 (en) 1991-08-14
FI910592L (fi) 1991-08-09
BR9100519A (pt) 1991-10-29

Similar Documents

Publication Publication Date Title
RU2100357C1 (ru) Гетероариламины или их фармацевтически приемлемые соли и фармацевтическая композиция на их основе
FI95909B (fi) Menetelmä terapeuttisesti käyttökelpoisten 3,4-bis(3-indolyyli)-1H-pyrroli-2,5-dionijohdannaisten valmistamiseksi sekä menetelmässä käyttökelpoiset välituotteet
PL166757B1 (pl) Sposób wytwarzania nowych trójpierscieniowych amin PL PL
US6258805B1 (en) Pyrroloazepine derivatives
JP3242653B2 (ja) ピロロアゼピン化合物
AU678435B2 (en) Substituted pyrroles
JPWO1993003032A1 (ja) ピロロアゼピン化合物
US6057317A (en) Heterocyclic compounds
JP3545332B2 (ja) 新規カンプトテシン類似化合物、それらの製造方法、及びそれらを含有する医薬組成物
US5965574A (en) Heteroaryl amines as novel acetylcholinesterase inhibitors
CS248020B2 (en) Production method of the (+)-enantiomere or (+-)-racemical 4a,9b-trans-hexahydro-1h-pyridoindole derivatives
US5428043A (en) Tricyclic-cyclic amines as novel cholinesterase inhibitors
Lamazzi et al. Synthesis of 4-substituted indolizidin-9-one amino acid derivatives
JP2006507280A (ja) 新規置換〔1,4〕ベンゾジオキシノ〔2,3−e〕イソインドール誘導体、それらの製造方法、及びそれらを含有する医薬組成物
JP2006506375A (ja) 置換ベンゾール〔e〕〔1,4〕オキサジノ〔3,2−g〕イソインドール誘導体、それらの製造方法、及びそれらを含有する医薬組成物