PL141782B1 - Method of obtaining epimers of 7 beta-malonamido-7 alpha-methoxy-3-tetazolylthiomethyl-1-destia-1-oxa-3-cephemocarboxylic-4 esters - Google Patents

Method of obtaining epimers of 7 beta-malonamido-7 alpha-methoxy-3-tetazolylthiomethyl-1-destia-1-oxa-3-cephemocarboxylic-4 esters Download PDF

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Publication number
PL141782B1
PL141782B1 PL1983242776A PL24277683A PL141782B1 PL 141782 B1 PL141782 B1 PL 141782B1 PL 1983242776 A PL1983242776 A PL 1983242776A PL 24277683 A PL24277683 A PL 24277683A PL 141782 B1 PL141782 B1 PL 141782B1
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PL
Poland
Prior art keywords
oxa
methoxy
epimers
epimer
product
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Application number
PL1983242776A
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English (en)
Polish (pl)
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PL242776A1 (en
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of PL242776A1 publication Critical patent/PL242776A1/xx
Publication of PL141782B1 publication Critical patent/PL141782B1/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL1983242776A 1982-07-02 1983-07-01 Method of obtaining epimers of 7 beta-malonamido-7 alpha-methoxy-3-tetazolylthiomethyl-1-destia-1-oxa-3-cephemocarboxylic-4 esters PL141782B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57116048A JPS597193A (ja) 1982-07-02 1982-07-02 マロニルメチル基の異性化方法

Publications (2)

Publication Number Publication Date
PL242776A1 PL242776A1 (en) 1984-08-13
PL141782B1 true PL141782B1 (en) 1987-08-31

Family

ID=14677411

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1983242776A PL141782B1 (en) 1982-07-02 1983-07-01 Method of obtaining epimers of 7 beta-malonamido-7 alpha-methoxy-3-tetazolylthiomethyl-1-destia-1-oxa-3-cephemocarboxylic-4 esters

Country Status (30)

Country Link
US (1) US4504658A (oth)
EP (1) EP0098545B1 (oth)
JP (1) JPS597193A (oth)
KR (1) KR890000812B1 (oth)
AR (1) AR242391A1 (oth)
AT (1) ATE19401T1 (oth)
AU (1) AU564850B2 (oth)
BG (1) BG37526A3 (oth)
CA (1) CA1192193A (oth)
CS (1) CS244940B2 (oth)
DD (1) DD210052A5 (oth)
DE (2) DE98545T1 (oth)
DK (1) DK160502C (oth)
EG (1) EG16539A (oth)
ES (1) ES523774A0 (oth)
FI (1) FI832407A7 (oth)
GB (1) GB2124217B (oth)
GR (1) GR78620B (oth)
HU (1) HU187944B (oth)
IE (1) IE55767B1 (oth)
IL (1) IL69146A (oth)
NO (1) NO832387L (oth)
NZ (1) NZ204627A (oth)
PH (1) PH21139A (oth)
PL (1) PL141782B1 (oth)
PT (1) PT76973B (oth)
RO (1) RO86355B (oth)
SU (1) SU1225488A3 (oth)
YU (1) YU44011B (oth)
ZA (1) ZA834495B (oth)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60123490A (ja) * 1983-12-07 1985-07-02 Shionogi & Co Ltd マロニルオキサセフェムカルボン酸誘導体
US4998060A (en) * 1989-07-12 1991-03-05 Pacific Scientific Company Fault indicator with hot stick clamping mechanism
KR100810810B1 (ko) * 2003-02-04 2008-03-06 에프. 호프만-라 로슈 아게 감마-세크레타제 억제제로서 말론아마이드 유도체
JP2006028154A (ja) * 2004-06-14 2006-02-02 Sumitomo Chemical Co Ltd 光学活性化合物の製造方法
CN102260280A (zh) * 2010-05-28 2011-11-30 上海医药工业研究院 拉氧头孢钠的制备方法
US9828324B2 (en) 2010-10-20 2017-11-28 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
KR20140020236A (ko) 2010-10-20 2014-02-18 바이오포믹스, 인크. 열 전달제 존재하에서의 빠른 회수를 사용하는 메틸렌 말로네이트의 합성
US9279022B1 (en) 2014-09-08 2016-03-08 Sirrus, Inc. Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions
US9249265B1 (en) 2014-09-08 2016-02-02 Sirrus, Inc. Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions
EP3517523A1 (en) 2011-10-19 2019-07-31 Sirrus, Inc. Multifunctional monomers and methods for making them
JP6345644B2 (ja) 2012-03-30 2018-06-20 シラス・インコーポレイテッド インク配合物およびコーティング配合物ならびにこれらを作製するための重合性の系
US9181365B2 (en) 2012-03-30 2015-11-10 Sirrus, Inc. Methods for activating polymerizable compositions, polymerizable systems, and products formed thereby
EP3153530B1 (en) 2012-03-30 2021-02-24 Sirrus, Inc. Composite and laminate articles and polymerizable systems for producing the same
WO2013181600A2 (en) 2012-06-01 2013-12-05 Bioformix Inc. Optical material and articles formed therefrom
WO2014078689A1 (en) 2012-11-16 2014-05-22 Bioformix Inc. Plastics bonding systems and methods
US10607910B2 (en) 2012-11-30 2020-03-31 Sirrus, Inc. Composite compositions for electronics applications
CN105008321A (zh) 2013-01-11 2015-10-28 瑟拉斯公司 经过双(羟甲基)丙二酸酯的途径获得亚甲基丙二酸酯的方法
US9416091B1 (en) 2015-02-04 2016-08-16 Sirrus, Inc. Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9315597B2 (en) 2014-09-08 2016-04-19 Sirrus, Inc. Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US10501400B2 (en) 2015-02-04 2019-12-10 Sirrus, Inc. Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9334430B1 (en) 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
US9518001B1 (en) 2016-05-13 2016-12-13 Sirrus, Inc. High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation
US10428177B2 (en) 2016-06-03 2019-10-01 Sirrus, Inc. Water absorbing or water soluble polymers, intermediate compounds, and methods thereof
US9617377B1 (en) 2016-06-03 2017-04-11 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9567475B1 (en) 2016-06-03 2017-02-14 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US10196481B2 (en) 2016-06-03 2019-02-05 Sirrus, Inc. Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof
KR102115644B1 (ko) * 2017-09-13 2020-05-27 주식회사 동도물산 7α-알콕시옥사세펨 중간체의 제조방법
CN112480147A (zh) * 2019-09-12 2021-03-12 杭州森泽医药科技有限公司 一种拉氧头孢中间体溶剂化物及其制备方法和表征

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3719667A (en) * 1970-08-24 1973-03-06 Lilly Co Eli Epimerization of 6-acylamido and 6-imido penicillin sulfoxide esters
US4167630A (en) * 1975-12-24 1979-09-11 Merck & Co., Inc. Process for epimerizing beta-lactam antibiotic compounds, and related products
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins
US4234596A (en) * 1976-11-19 1980-11-18 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-(1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
US4259485A (en) * 1979-04-24 1981-03-31 Eli Lilly And Company Crystallization process
US4252953A (en) * 1979-05-01 1981-02-24 Eli Lilly And Company Antibiotic crystalline epimer
US4320055A (en) * 1980-04-07 1982-03-16 Eli Lilly And Company Process for penicillin epimerization
JPS5711909A (en) * 1980-06-23 1982-01-21 Shionogi & Co Ltd Stable freeze-dried preparation of beta-lactam

Also Published As

Publication number Publication date
ES8500954A1 (es) 1984-11-01
GR78620B (oth) 1984-09-27
DE98545T1 (de) 1984-08-16
FI832407A0 (fi) 1983-06-30
FI832407L (fi) 1984-01-03
PT76973B (en) 1986-01-24
AU564850B2 (en) 1987-08-27
YU44011B (en) 1990-02-28
YU144583A (en) 1986-02-28
FI832407A7 (fi) 1984-01-03
DK304983D0 (da) 1983-07-01
HU187944B (en) 1986-03-28
JPH0149271B2 (oth) 1989-10-24
AU1649683A (en) 1984-01-05
DK160502B (da) 1991-03-18
PH21139A (en) 1987-07-27
DK160502C (da) 1991-08-26
CA1192193A (en) 1985-08-20
IL69146A (en) 1987-01-30
IE55767B1 (en) 1991-01-16
EP0098545A1 (en) 1984-01-18
IE831527L (en) 1984-01-02
KR840005450A (ko) 1984-11-12
GB2124217A (en) 1984-02-15
RO86355B (ro) 1985-03-31
EG16539A (en) 1989-03-30
SU1225488A3 (ru) 1986-04-15
GB2124217B (en) 1985-09-04
KR890000812B1 (ko) 1989-04-08
ES523774A0 (es) 1984-11-01
DD210052A5 (de) 1984-05-30
ZA834495B (en) 1984-07-25
AR242391A1 (es) 1993-03-31
DK304983A (da) 1984-01-03
EP0098545B1 (en) 1986-04-23
PT76973A (en) 1983-08-01
NO832387L (no) 1984-01-03
DE3363161D1 (en) 1986-05-28
BG37526A3 (bg) 1985-06-14
RO86355A (ro) 1985-03-15
JPS597193A (ja) 1984-01-14
ATE19401T1 (de) 1986-05-15
CS244940B2 (en) 1986-08-14
NZ204627A (en) 1986-04-11
PL242776A1 (en) 1984-08-13
US4504658A (en) 1985-03-12
GB8317634D0 (en) 1983-08-03
CS503683A2 (en) 1985-09-17

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