PL139768B1 - Method of obtaining novel derivatives of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline - Google Patents
Method of obtaining novel derivatives of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline Download PDFInfo
- Publication number
- PL139768B1 PL139768B1 PL1983242311A PL24231183A PL139768B1 PL 139768 B1 PL139768 B1 PL 139768B1 PL 1983242311 A PL1983242311 A PL 1983242311A PL 24231183 A PL24231183 A PL 24231183A PL 139768 B1 PL139768 B1 PL 139768B1
- Authority
- PL
- Poland
- Prior art keywords
- ethanol
- mol
- ether
- methyl
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU179882A HU186519B (en) | 1982-06-04 | 1982-06-04 | Process for producing 8-bracket-carbamoyl-amino-bracket-closed-4-aryl-2-methyl-tetrahydro-isoquinoline derivatives |
| HU821797A HU186518B (en) | 1982-06-04 | 1982-06-04 | Process for producing 8-bracket-amino-acyl-amino-bracket closed-4-aryl-2-methyl-1,2,3,4-tetrahydro-isoquinoline derivatives |
| HU821799A HU190019B (hu) | 1982-06-04 | 1982-06-04 | Eljárás 8-(alkoxi'karbonil-amino)-4-áril-2-metil-tetrahidro -izokinolin-származékok előállítására |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL242311A1 PL242311A1 (en) | 1985-01-16 |
| PL139768B1 true PL139768B1 (en) | 1987-02-28 |
Family
ID=27269976
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1983242311A PL139768B1 (en) | 1982-06-04 | 1983-06-01 | Method of obtaining novel derivatives of 8-aminoacylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249636A PL140094B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-alkoxycarbonylamino-4-aryl-3-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249638A PL140034B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-alkoxycarbonyl-amino-4-aryl-3-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249639A PL140164B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-carbonylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249637A PL140035B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-carbonylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1983249636A PL140094B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-alkoxycarbonylamino-4-aryl-3-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249638A PL140034B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-alkoxycarbonyl-amino-4-aryl-3-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249639A PL140164B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-carbonylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline |
| PL1983249637A PL140035B1 (en) | 1982-06-04 | 1983-06-01 | Process for preparing novel derivatives of 8-carbonylamino-4-aryl-2-methyl-1,2,3,4-tetrahydroisoquinoline |
Country Status (19)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0314828B1 (de) * | 1987-11-03 | 1991-05-29 | S O "Pharmachim" | 4-Phenyl-1,2,3,4-tetrahydroisochinoline als Ulcusmittel |
| US5552412A (en) * | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
| DE60038185T2 (de) * | 1999-11-03 | 2009-02-19 | Amr Technology, Inc. | Arly- und heteroaryl-substituierte tetrahydroisoquinoline und ihre verwendung als hemmer der wiederaufnahme von norepinephrin, dopamin und serotonin |
| PL378754A1 (pl) * | 2003-03-03 | 2006-05-15 | F.Hoffmann-La Roche Ag | 2,5- i 2,6-Podstawione tetrahydroizochinoliny do stosowania jako modulatory 5-HT6 |
| RU2320654C1 (ru) * | 2006-05-24 | 2008-03-27 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) | 2,2-ДИМЕТИЛ-4-(4,6-ДИМЕТИЛ-2-ПИРИДОН-3-ИЛ)-1,2-ДИГИДРО-БЕНЗО[f]ИЗОХИНОЛИНА ГИДРОХЛОРИД, ПРОЯВЛЯЮЩИЙ ПРЯМОЕ АНТИКОАГУЛЯНТНОЕ ДЕЙСТВИЕ |
| ITTO20060599A1 (it) | 2006-08-11 | 2008-02-12 | Itw Construction Products Ital | Organo di ancoraggio di strutture in legno o metallo ad una parete |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1153471A (en) * | 1965-04-09 | 1969-05-29 | Wellcome Found | Antiprotozoal 8-Aminoquinoline Derivatives |
| US3674791A (en) * | 1968-03-26 | 1972-07-04 | Marion Laboratories Inc | Benzamido 2 lower alkyl decahydroisoquinolines |
| GB1453606A (en) * | 1972-12-22 | 1976-10-27 | Siphar Sa | Method for synthesis of plus-minus-glaziovine |
| US3910915A (en) * | 1973-07-23 | 1975-10-07 | Searle & Co | 1-Aryl-2-{8 (substituted amino)alkanoyl{9 -1,2,3,4-tetrahydroisoquinolines |
| DE2724610A1 (de) * | 1977-06-01 | 1978-12-14 | Hoechst Ag | 4-phenyl-8-amino-tetrahydroisochinoline |
| DE2811361A1 (de) * | 1978-03-16 | 1979-09-27 | Hoechst Ag | Neue isochinolinaldehyde und verfahren zu ihrer herstellung |
| DE2818423A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1983
- 1983-05-30 PH PH28981A patent/PH19604A/en unknown
- 1983-06-01 PL PL1983242311A patent/PL139768B1/pl unknown
- 1983-06-01 PL PL1983249636A patent/PL140094B1/pl unknown
- 1983-06-01 PL PL1983249638A patent/PL140034B1/pl unknown
- 1983-06-01 PL PL1983249639A patent/PL140164B1/pl unknown
- 1983-06-01 PL PL1983249637A patent/PL140035B1/pl unknown
- 1983-06-02 SE SE8303131A patent/SE8303131L/xx not_active Application Discontinuation
- 1983-06-02 CS CS833984A patent/CS247164B2/cs unknown
- 1983-06-02 NL NL8301960A patent/NL8301960A/xx not_active Application Discontinuation
- 1983-06-02 YU YU1222/83A patent/YU42865B/xx unknown
- 1983-06-02 GR GR71542A patent/GR77482B/el unknown
- 1983-06-02 FI FI831982A patent/FI831982L/fi not_active Application Discontinuation
- 1983-06-03 US US06/500,969 patent/US4537895A/en not_active Expired - Fee Related
- 1983-06-03 CA CA000429646A patent/CA1198733A/en not_active Expired
- 1983-06-03 AT AT0204383A patent/AT384806B/de not_active IP Right Cessation
- 1983-06-03 SU SU833604150A patent/SU1207393A3/ru active
- 1983-06-03 CH CH3048/83A patent/CH654833A5/de not_active IP Right Cessation
- 1983-06-03 DD DD83251735A patent/DD210684A5/de unknown
- 1983-06-03 DE DE19833320028 patent/DE3320028A1/de active Granted
- 1983-06-03 DK DK254983A patent/DK254983A/da not_active Application Discontinuation
- 1983-06-03 ES ES522976A patent/ES522976A0/es active Granted
- 1983-06-03 GB GB08315293A patent/GB2124209B/en not_active Expired
- 1983-06-03 FR FR8309233A patent/FR2528044B1/fr not_active Expired
-
1984
- 1984-03-22 SU SU843713729A patent/SU1329620A3/ru active
- 1984-03-22 SU SU843714140A patent/SU1375130A3/ru active
-
1985
- 1985-05-14 ES ES543157A patent/ES8607939A1/es not_active Expired
- 1985-05-14 ES ES543158A patent/ES8607940A1/es not_active Expired
- 1985-07-10 SU SU853922993A patent/SU1400505A3/ru active
- 1985-09-30 YU YU1554/85A patent/YU43419B/xx unknown
-
1986
- 1986-02-01 ES ES551560A patent/ES8702361A1/es not_active Expired
- 1986-02-01 ES ES551559A patent/ES8701729A1/es not_active Expired
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