GB1153471A - Antiprotozoal 8-Aminoquinoline Derivatives - Google Patents

Antiprotozoal 8-Aminoquinoline Derivatives

Info

Publication number
GB1153471A
GB1153471A GB1508865A GB1508865A GB1153471A GB 1153471 A GB1153471 A GB 1153471A GB 1508865 A GB1508865 A GB 1508865A GB 1508865 A GB1508865 A GB 1508865A GB 1153471 A GB1153471 A GB 1153471A
Authority
GB
United Kingdom
Prior art keywords
formula
compounds
antiprotozoal
aminoquinoline derivatives
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1508865A
Inventor
Leslie Percy Walls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB1508865A priority Critical patent/GB1153471A/en
Priority to BR17858166A priority patent/BR6678581D0/en
Publication of GB1153471A publication Critical patent/GB1153471A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,153,471. Piperazine derivatives. WELLCOME FOUNDATION Ltd. 19 May, 1966 [9 April, 1965], No. 15088/65. Heading C2C. Compounds of the Formula (I) (n = 5 or 6) and their acid addition salts are prepared by standard methods, e.g. reducing a compound of the Formula (II) (X = CO.Z, Z.CO or CO.Y.CO, in which Z = (CH 2 ) 4 or 5 and Y = (CH 2 ) 3 or 4 ) with a metal hydride and hydrolysing the product, optionally followed by salt formation. The preparation of starting materials of Formula (II) and salts thereof is described. The compounds of the invention are active against T. cruzi, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB1508865A 1965-04-09 1965-04-09 Antiprotozoal 8-Aminoquinoline Derivatives Expired GB1153471A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB1508865A GB1153471A (en) 1965-04-09 1965-04-09 Antiprotozoal 8-Aminoquinoline Derivatives
BR17858166A BR6678581D0 (en) 1965-04-09 1966-04-11 PROCESS TO PREPARE DERIVATIVES FROM 8 AMINO QUINOLINA

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1508865A GB1153471A (en) 1965-04-09 1965-04-09 Antiprotozoal 8-Aminoquinoline Derivatives

Publications (1)

Publication Number Publication Date
GB1153471A true GB1153471A (en) 1969-05-29

Family

ID=10052819

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1508865A Expired GB1153471A (en) 1965-04-09 1965-04-09 Antiprotozoal 8-Aminoquinoline Derivatives

Country Status (2)

Country Link
BR (1) BR6678581D0 (en)
GB (1) GB1153471A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537895A (en) * 1982-04-04 1985-08-27 Egyt Gyogyszervegyeszeti Gyar Isoquinoline derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537895A (en) * 1982-04-04 1985-08-27 Egyt Gyogyszervegyeszeti Gyar Isoquinoline derivatives

Also Published As

Publication number Publication date
BR6678581D0 (en) 1973-09-18

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee