PH26514A - Cell lines and their use for the production of proteins - Google Patents
Cell lines and their use for the production of proteins Download PDFInfo
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- PH26514A PH26514A PH30049A PH30049A PH26514A PH 26514 A PH26514 A PH 26514A PH 30049 A PH30049 A PH 30049A PH 30049 A PH30049 A PH 30049A PH 26514 A PH26514 A PH 26514A
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- Philippines
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- tpa
- serum
- pro
- cell line
- cells
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- HOVAGTYPODGVJG-VEIUFWFVSA-N methyl alpha-D-mannoside Chemical compound CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O HOVAGTYPODGVJG-VEIUFWFVSA-N 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- MGCQZNBCJBRZDT-UHFFFAOYSA-N midodrine hydrochloride Chemical compound [H+].[Cl-].COC1=CC=C(OC)C(C(O)CNC(=O)CN)=C1 MGCQZNBCJBRZDT-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
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- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 description 1
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- FESBVLZDDCQLFY-UHFFFAOYSA-N sete Chemical compound [Te]=[Se] FESBVLZDDCQLFY-UHFFFAOYSA-N 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- PEVNIEPIRVCPAW-UHFFFAOYSA-J sodium;1h-imidazole;methylsulfinylmethane;ruthenium(3+);tetrachloride Chemical compound [Na+].[Cl-].[Cl-].[Cl-].[Cl-].[Ru+3].CS(C)=O.C1=CNC=N1 PEVNIEPIRVCPAW-UHFFFAOYSA-J 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000011146 sterile filtration Methods 0.000 description 1
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- 239000012581 transferrin Substances 0.000 description 1
- JREYOWJEWZVAOR-UHFFFAOYSA-N triazanium;[3-methylbut-3-enoxy(oxido)phosphoryl] phosphate Chemical compound [NH4+].[NH4+].[NH4+].CC(=C)CCOP([O-])(=O)OP([O-])([O-])=O JREYOWJEWZVAOR-UHFFFAOYSA-N 0.000 description 1
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- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA829576 | 1982-12-30 | ||
| ZA834576 | 1983-06-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH26514A true PH26514A (en) | 1992-08-07 |
Family
ID=27134272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH30049A PH26514A (en) | 1982-12-30 | 1983-12-29 | Cell lines and their use for the production of proteins |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4798796A (pt) |
| EP (1) | EP0113319B1 (pt) |
| JP (3) | JPH0632607B2 (pt) |
| KR (1) | KR900008740B1 (pt) |
| AU (1) | AU579812B2 (pt) |
| CA (1) | CA1267620A (pt) |
| DE (1) | DE3382390D1 (pt) |
| DK (1) | DK607083A (pt) |
| ES (2) | ES8600389A1 (pt) |
| FI (1) | FI81377C (pt) |
| GR (1) | GR78779B (pt) |
| HU (1) | HU197766B (pt) |
| IL (1) | IL70573A (pt) |
| NO (1) | NO169497C (pt) |
| NZ (1) | NZ206699A (pt) |
| PH (1) | PH26514A (pt) |
| PT (1) | PT77897B (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA831399B (en) * | 1982-03-05 | 1984-02-29 | Health Lab Service Board | New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them |
| EP0112122B1 (en) * | 1982-12-14 | 1991-08-28 | South African Inventions Development Corporation | Plasminogen activator |
| US5079159A (en) * | 1983-12-27 | 1992-01-07 | Genetics Institute, Inc. | Method for making tissue plasminogen activator |
| JP2648301B2 (ja) * | 1983-12-27 | 1997-08-27 | ジエネテイツクス・インスチチユ−ト・インコ−ポレ−テツド | 真核細胞の形質転換のための補助ｄｎａを含むベクター |
| US4757005A (en) * | 1984-04-19 | 1988-07-12 | Miles Inc. | Method and cell line for obtaining plasminogen activators |
| US4929444A (en) * | 1985-05-28 | 1990-05-29 | Burroughs Wellcome Co. | Low pH pharmaceutical formulation containing t-PA |
| DE3531966A1 (de) * | 1985-09-07 | 1987-03-12 | Arnim Ulrich Christoph Von | Verfahren zur langzeit-zuechtung beliebiger endothelzellen, methode zu ihrer identifizierung und charakterisierung und ihre verwendung fuer diagnose und klaerung der aetiopatogenese von krankheitszustaenden |
| US4889808A (en) * | 1985-10-01 | 1989-12-26 | American Home Products | Method of enchancing t-PA and SCU-PA production |
| IL82746A (en) * | 1986-06-06 | 1994-10-07 | Genentech Inc | A process for producing a biologically active tissue plasminogen activator |
| JPS63196268A (ja) * | 1987-02-10 | 1988-08-15 | Kanegafuchi Chem Ind Co Ltd | 無血清培地で継代増殖可能な形質転換細胞、その育種方法およびその細胞による蛋白質の生産方法 |
| WO1989000605A1 (en) * | 1987-07-16 | 1989-01-26 | Codon | Transfected cells containing plasmids having genes oriented in opposing directions and methods of obtaining the same |
| JPS6427472A (en) * | 1987-07-21 | 1989-01-30 | Meiji Milk Prod Co Ltd | Production of human tissue plasminogen activator and cell strain using therein |
| US5128449A (en) * | 1988-07-05 | 1992-07-07 | The University Of Tennessee Research Corporation | Polypeptide and a method for its production |
| DE3829244A1 (de) * | 1988-08-29 | 1990-03-01 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von einkettigem t-pa |
| FR2657884B1 (fr) * | 1990-02-05 | 1994-09-02 | Tm Innovation | Procede pour la preparation du facteur viii humain et d'analogues du facteur viii. |
| US5141862A (en) * | 1990-04-17 | 1992-08-25 | Smithkline Beecham Corporation | Method of purifying tpa or plasminogen activator using a tripeptide of the formula: -X-Y-argininal wherein X and Y are selected from the group consisting of pro,phe,trp and tyr |
| US5227297A (en) * | 1990-04-17 | 1993-07-13 | Smithkline Beecham Corporation | Affinity purification ligands |
| US5122469A (en) * | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| US5405772A (en) * | 1993-06-18 | 1995-04-11 | Amgen Inc. | Medium for long-term proliferation and development of cells |
| USH1532H (en) * | 1993-11-03 | 1996-05-07 | Genetics Institute, Inc. | Adaption of mammalian cell lines to high cell densities |
| US5698433A (en) * | 1994-11-10 | 1997-12-16 | Immuno Ag | Method for producing influenza virus and vaccine |
| US5756341A (en) * | 1994-11-10 | 1998-05-26 | Immuno Ag | Method for controlling the infectivity of viruses |
| US6146873A (en) * | 1994-11-10 | 2000-11-14 | Baxter Aktiengesellschaft | Production of orthomyxoviruses in monkey kidney cells using protein-free media |
| US5753489A (en) * | 1994-11-10 | 1998-05-19 | Immuno Ag | Method for producing viruses and vaccines in serum-free culture |
| US6033660A (en) * | 1995-05-10 | 2000-03-07 | Genentech, Inc. | Method of treating a nervous system injury with cultured schwann cells |
| US5849585A (en) * | 1995-05-10 | 1998-12-15 | Genetech, Inc. | Isolating and culturing Schwann cells |
| US5721139A (en) * | 1995-05-10 | 1998-02-24 | Genentech, Inc. | Isolating and culturing schwann cells |
| US5714385A (en) * | 1995-05-10 | 1998-02-03 | Genentech, Inc. | Media for culturing schwann cells |
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| EP2121903A2 (en) * | 2007-02-16 | 2009-11-25 | Fondazione Centro San Raffaele del Monte Tabor | Mitogen independence identifies a highly malignant population of tumor stem cells |
| JP4891946B2 (ja) * | 2008-05-19 | 2012-03-07 | 大成ロテック株式会社 | 防水層の施工方法、アスファルトパネルの製造方法及びアスファルトパネル用型枠 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904480A (en) * | 1972-10-24 | 1975-09-09 | Lilly Co Eli | Enhanced production of plasminogen activator |
| NL8003402A (nl) * | 1980-06-11 | 1982-01-04 | Leuven Res & Dev Vzw | Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking. |
| JPS5774085A (en) * | 1980-10-25 | 1982-05-10 | Ajinomoto Co Inc | Culture medium for cells originating from lymphocytes |
| US4517293A (en) * | 1981-03-26 | 1985-05-14 | Hooper Trading Co. N.V. | High yield process for in vitro production of serum-free and mitogen-free interleukin-2 using a roller bottle culture system |
| US4448879A (en) * | 1981-03-26 | 1984-05-15 | Hooper Trading Company | High yield process for in vitro production of serum-free and mitogen-free interleukin-2 |
| US4544632A (en) * | 1981-06-12 | 1985-10-01 | Yuichi Yamamura | Human T cell lines and method of producing same |
| EP0112122B1 (en) * | 1982-12-14 | 1991-08-28 | South African Inventions Development Corporation | Plasminogen activator |
| JPS59169489A (ja) * | 1983-03-15 | 1984-09-25 | Otsuka Pharmaceut Co Ltd | ヒト培養株化細胞 |
| WO1984004327A1 (en) * | 1983-04-27 | 1984-11-08 | Harvard College | Method and products for detection of human t cell leukemia virus |
-
1983
- 1983-12-22 NZ NZ206699A patent/NZ206699A/xx unknown
- 1983-12-23 EP EP83810621A patent/EP0113319B1/en not_active Expired - Lifetime
- 1983-12-23 DE DE8383810621T patent/DE3382390D1/de not_active Expired - Lifetime
- 1983-12-27 PT PT77897A patent/PT77897B/pt not_active IP Right Cessation
- 1983-12-28 IL IL70573A patent/IL70573A/xx not_active IP Right Cessation
- 1983-12-28 GR GR73377A patent/GR78779B/el unknown
- 1983-12-28 FI FI834830A patent/FI81377C/fi not_active IP Right Cessation
- 1983-12-28 CA CA000444308A patent/CA1267620A/en not_active Expired - Lifetime
- 1983-12-29 NO NO83834866A patent/NO169497C/no unknown
- 1983-12-29 AU AU22963/83A patent/AU579812B2/en not_active Ceased
- 1983-12-29 HU HU834513A patent/HU197766B/hu not_active IP Right Cessation
- 1983-12-29 PH PH30049A patent/PH26514A/en unknown
- 1983-12-29 JP JP58252491A patent/JPH0632607B2/ja not_active Expired - Lifetime
- 1983-12-29 DK DK607083A patent/DK607083A/da unknown
- 1983-12-30 KR KR1019830006314A patent/KR900008740B1/ko not_active IP Right Cessation
- 1983-12-30 ES ES528570A patent/ES8600389A1/es not_active Expired
-
1985
- 1985-05-28 ES ES543559A patent/ES8606396A1/es not_active Expired
-
1986
- 1986-04-17 US US06/854,729 patent/US4798796A/en not_active Expired - Lifetime
-
1988
- 1988-10-04 US US07/253,190 patent/US5147790A/en not_active Expired - Fee Related
-
1993
- 1993-08-02 JP JP5191357A patent/JP2534020B2/ja not_active Expired - Lifetime
-
1995
- 1995-12-13 JP JP7324299A patent/JPH08205859A/ja active Pending
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