PH26422A - 5-substituted ornithine derivatives - Google Patents

5-substituted ornithine derivatives Download PDF

Info

Publication number
PH26422A
PH26422A PH38131A PH38131A PH26422A PH 26422 A PH26422 A PH 26422A PH 38131 A PH38131 A PH 38131A PH 38131 A PH38131 A PH 38131A PH 26422 A PH26422 A PH 26422A
Authority
PH
Philippines
Prior art keywords
group
ornithine
acid
substituted
solution
Prior art date
Application number
PH38131A
Other languages
English (en)
Inventor
Fritz E Gerhart
Nikolaus J Seiler
Original Assignee
Merrell Dow France
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow France, Merrell Dow Pharma filed Critical Merrell Dow France
Publication of PH26422A publication Critical patent/PH26422A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
PH38131A 1988-02-05 1989-01-31 5-substituted ornithine derivatives PH26422A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88400275A EP0326766B1 (en) 1988-02-05 1988-02-05 5-substituted ornithine derivatives

Publications (1)

Publication Number Publication Date
PH26422A true PH26422A (en) 1992-07-15

Family

ID=8200349

Family Applications (1)

Application Number Title Priority Date Filing Date
PH38131A PH26422A (en) 1988-02-05 1989-01-31 5-substituted ornithine derivatives

Country Status (22)

Country Link
US (1) US4902719A (da)
EP (1) EP0326766B1 (da)
JP (1) JP2816431B2 (da)
KR (1) KR0150634B1 (da)
CN (1) CN1027891C (da)
AR (1) AR244657A1 (da)
AT (1) ATE77367T1 (da)
AU (1) AU612229B2 (da)
CA (1) CA1311767C (da)
DE (1) DE3872213T2 (da)
DK (1) DK172113B1 (da)
ES (1) ES2041815T3 (da)
FI (1) FI90530C (da)
GR (1) GR3005551T3 (da)
HU (1) HU204770B (da)
IE (1) IE63162B1 (da)
IL (1) IL89145A (da)
NO (1) NO176242C (da)
NZ (1) NZ227783A (da)
PH (1) PH26422A (da)
PT (1) PT89637B (da)
ZA (1) ZA89833B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016035A1 (en) * 1990-04-26 1991-10-31 The Procter & Gamble Company Chelator compositions comprising alpha-diamine compounds
EP0609630A1 (en) * 1993-02-05 1994-08-10 Merrell Dow Pharmaceuticals Inc. Use of inhibitors of ornithine aminotransferase for the manufacture of a medicament for the treatment of Alzheimer's disease
US5677350A (en) * 1995-06-07 1997-10-14 Wisconsin Alumni Research Foundation Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes
GB9617822D0 (en) * 1996-08-27 1996-10-09 Lilly Industries Ltd Pharmaceutical compounds
US6566330B1 (en) 1996-10-22 2003-05-20 Medical University Of South Carolina Foundation Research Development Positively charged non-natural amino acids, methods of making and using thereof in peptides
US6043218A (en) 1996-10-22 2000-03-28 Medical University Of South Carolina Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
US7166234B1 (en) * 2000-10-26 2007-01-23 Integrated Biomedical Technology, Inc. Dialdehyde assay
US6911544B2 (en) * 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
EP3062175B1 (en) 2013-10-21 2018-09-05 Fuji Electric Co., Ltd. Control system design assist device, control system design assist program, control system design assist method, operation change amount calculation device, and control device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4326071A (en) * 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
PH16634A (en) * 1980-06-16 1983-12-05 Merrell Dow Pharma Method of inhibiting the growth of protozoa
US4668703A (en) * 1983-07-07 1987-05-26 Syntex (U.S.A.) Inc. γ-allenyl-γ-aminobutyric acids

Also Published As

Publication number Publication date
GR3005551T3 (da) 1993-06-07
FI890477A0 (fi) 1989-02-01
PT89637B (pt) 1994-02-28
ZA89833B (en) 1989-10-25
DK172113B1 (da) 1997-11-10
CN1037142A (zh) 1989-11-15
EP0326766B1 (en) 1992-06-17
JPH021435A (ja) 1990-01-05
CA1311767C (en) 1992-12-22
US4902719A (en) 1990-02-20
HUT49320A (en) 1989-09-28
PT89637A (pt) 1989-10-04
KR0150634B1 (ko) 1998-10-15
IL89145A0 (en) 1989-09-10
KR890012942A (ko) 1989-09-20
HU204770B (en) 1992-02-28
ATE77367T1 (de) 1992-07-15
NO890455D0 (no) 1989-02-03
IL89145A (en) 1993-08-18
AU2951589A (en) 1989-08-10
JP2816431B2 (ja) 1998-10-27
EP0326766A1 (en) 1989-08-09
DE3872213T2 (de) 1993-01-28
AU612229B2 (en) 1991-07-04
DK51589D0 (da) 1989-02-03
DK51589A (da) 1989-08-06
CN1027891C (zh) 1995-03-15
IE63162B1 (en) 1995-03-22
IE890356L (en) 1989-08-05
FI90530C (fi) 1994-02-25
NO176242C (no) 1995-03-01
AR244657A1 (es) 1993-11-30
FI90530B (fi) 1993-11-15
NO176242B (no) 1994-11-21
NO890455L (no) 1989-08-07
FI890477A (fi) 1989-08-06
DE3872213D1 (de) 1992-07-23
ES2041815T3 (es) 1993-12-01
NZ227783A (en) 1990-12-21

Similar Documents

Publication Publication Date Title
US6579890B1 (en) Matrix metalloprotease inhibitors
DK174922B1 (da) Spiro-substituerede glutaramid-derivater, disse forbindelser til medicinsk anvendelse samt farmaceutiske præparater indeholdende forbindelserne
EP0358398B1 (en) Cycloalkyl-substituted glutaramide antihypertensive agents
JP2529172B2 (ja) アミノ酸から誘導される新規な光学異性体と、その製造方法と、その医薬への応用
JPH05503720A (ja) ペプチジル誘導体
JPH0472839B2 (da)
CZ293759B6 (cs) Substituovaná cyklická aminokyselina, její použití a farmaceutický prostředek na její bázi
SK64993A3 (en) Hydroxamic acid derivatives, method of their preparation and medicaments with their content
CS247159B2 (en) Method of cis,endo-2-azabicyclo(3,3,1) octal-3-carboxyl acid's derivatives production
JP2001511172A (ja) 特に神経興奮薬性アミノ酸に感受性をもつ中枢神経系受容体のエフェクターを構成する化合物、その製造およびその生物学的利用
JPH07500577A (ja) レトロウイルス性プロテアーゼ・インヒビター
PH26422A (en) 5-substituted ornithine derivatives
PL79309B1 (da)
JPH0559105B2 (da)
US5935988A (en) Tolerability of pharmaceutically active β-amino acids
CA2069112A1 (en) Carboxyalkylcarbonyl aminoacid endopeptidase inhibitors
EP0333000B1 (en) Peptides with inhibitory activity of enzymatic systems, process for their preparation and pharmaceutical compositions containing them
JPS5892646A (ja) ベンジリデン誘導体
JP3250806B2 (ja) N−(メルカプトアシル)アミノ酸と、その製造方法と、その治療での使用と、それを含む医薬組成物
EP0110484B1 (en) Derivatives of aminopyridinecarboxylic acids, methods for their preparation and pharmaceutical compositions containing them
PT93179A (pt) Processo para a preparacao de agentes diureticos glutaramida substituida com cicloalquilo
EP0009326A2 (en) Pyrrolyl keto and amino acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them
JPH0819152B2 (ja) 二環式アミノ酸の新規誘導体およびそれらの製法
RU2173146C2 (ru) Производные полициклических алкалоидов как антагонисты nmda-рецептора
JPS59137451A (ja) インダン誘導体