DE3872213T2 - 5-substituierte ornithin-derivate. - Google Patents

5-substituierte ornithin-derivate.

Info

Publication number
DE3872213T2
DE3872213T2 DE8888400275T DE3872213T DE3872213T2 DE 3872213 T2 DE3872213 T2 DE 3872213T2 DE 8888400275 T DE8888400275 T DE 8888400275T DE 3872213 T DE3872213 T DE 3872213T DE 3872213 T2 DE3872213 T2 DE 3872213T2
Authority
DE
Germany
Prior art keywords
ornithin
derivatives
substituted
substituted ornithin
ornithin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888400275T
Other languages
English (en)
Other versions
DE3872213D1 (de
Inventor
Fritz E Gerhart
Nikolaus J Seiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE3872213D1 publication Critical patent/DE3872213D1/de
Application granted granted Critical
Publication of DE3872213T2 publication Critical patent/DE3872213T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE8888400275T 1988-02-05 1988-02-05 5-substituierte ornithin-derivate. Expired - Lifetime DE3872213T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88400275A EP0326766B1 (de) 1988-02-05 1988-02-05 5-Substituierte Ornithin-Derivate

Publications (2)

Publication Number Publication Date
DE3872213D1 DE3872213D1 (de) 1992-07-23
DE3872213T2 true DE3872213T2 (de) 1993-01-28

Family

ID=8200349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888400275T Expired - Lifetime DE3872213T2 (de) 1988-02-05 1988-02-05 5-substituierte ornithin-derivate.

Country Status (22)

Country Link
US (1) US4902719A (de)
EP (1) EP0326766B1 (de)
JP (1) JP2816431B2 (de)
KR (1) KR0150634B1 (de)
CN (1) CN1027891C (de)
AR (1) AR244657A1 (de)
AT (1) ATE77367T1 (de)
AU (1) AU612229B2 (de)
CA (1) CA1311767C (de)
DE (1) DE3872213T2 (de)
DK (1) DK172113B1 (de)
ES (1) ES2041815T3 (de)
FI (1) FI90530C (de)
GR (1) GR3005551T3 (de)
HU (1) HU204770B (de)
IE (1) IE63162B1 (de)
IL (1) IL89145A (de)
NO (1) NO176242C (de)
NZ (1) NZ227783A (de)
PH (1) PH26422A (de)
PT (1) PT89637B (de)
ZA (1) ZA89833B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2079486C (en) * 1990-04-26 1999-11-02 Rodney Dean Bush Chelator compositions comprising alpha- diamine compounds
EP0609630A1 (de) * 1993-02-05 1994-08-10 Merrell Dow Pharmaceuticals Inc. Verwendung von Ornithin-Aminotransferase-Inhibitoren zur Herstellung eines Arzneimittels zur Behandlung der alzheimerschen Krankheit
US5677350A (en) * 1995-06-07 1997-10-14 Wisconsin Alumni Research Foundation Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes
GB9617822D0 (en) * 1996-08-27 1996-10-09 Lilly Industries Ltd Pharmaceutical compounds
US6043218A (en) 1996-10-22 2000-03-28 Medical University Of South Carolina Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
US6566330B1 (en) 1996-10-22 2003-05-20 Medical University Of South Carolina Foundation Research Development Positively charged non-natural amino acids, methods of making and using thereof in peptides
US7166234B1 (en) * 2000-10-26 2007-01-23 Integrated Biomedical Technology, Inc. Dialdehyde assay
US6911544B2 (en) * 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
EP3062175B1 (de) 2013-10-21 2018-09-05 Fuji Electric Co., Ltd. Unterstützungsvorrichtung für steuersystemdesign, unterstützungsprogramm für steuersystemdesign, unterstützungsverfahren für steuersystemdesign, kalkulationsvorrichtung für betriebsänderungsquantität und steuerungsvorrichtung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
US4326071A (en) * 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
CA1174603A (en) * 1980-06-16 1984-09-18 Albert Sjoerdsma Method of inhibiting the growth of protozoa
US4668703A (en) * 1983-07-07 1987-05-26 Syntex (U.S.A.) Inc. γ-allenyl-γ-aminobutyric acids

Also Published As

Publication number Publication date
ZA89833B (en) 1989-10-25
CN1037142A (zh) 1989-11-15
HU204770B (en) 1992-02-28
AU612229B2 (en) 1991-07-04
FI90530C (fi) 1994-02-25
DK51589A (da) 1989-08-06
DK51589D0 (da) 1989-02-03
ATE77367T1 (de) 1992-07-15
AU2951589A (en) 1989-08-10
DE3872213D1 (de) 1992-07-23
GR3005551T3 (de) 1993-06-07
JP2816431B2 (ja) 1998-10-27
JPH021435A (ja) 1990-01-05
PH26422A (en) 1992-07-15
PT89637B (pt) 1994-02-28
AR244657A1 (es) 1993-11-30
IE890356L (en) 1989-08-05
ES2041815T3 (es) 1993-12-01
IL89145A (en) 1993-08-18
FI890477A (fi) 1989-08-06
HUT49320A (en) 1989-09-28
DK172113B1 (da) 1997-11-10
US4902719A (en) 1990-02-20
PT89637A (pt) 1989-10-04
IL89145A0 (en) 1989-09-10
CA1311767C (en) 1992-12-22
NZ227783A (en) 1990-12-21
IE63162B1 (en) 1995-03-22
KR890012942A (ko) 1989-09-20
NO176242C (no) 1995-03-01
EP0326766B1 (de) 1992-06-17
NO890455L (no) 1989-08-07
CN1027891C (zh) 1995-03-15
FI890477A0 (fi) 1989-02-01
NO176242B (no) 1994-11-21
NO890455D0 (no) 1989-02-03
FI90530B (fi) 1993-11-15
KR0150634B1 (ko) 1998-10-15
EP0326766A1 (de) 1989-08-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition