PH25022A - Novel (1h-imidazol-1-ylmethyl) substituted benzimidazole derivatives - Google Patents
Novel (1h-imidazol-1-ylmethyl) substituted benzimidazole derivativesInfo
- Publication number
- PH25022A PH25022A PH35811A PH35811A PH25022A PH 25022 A PH25022 A PH 25022A PH 35811 A PH35811 A PH 35811A PH 35811 A PH35811 A PH 35811A PH 25022 A PH25022 A PH 25022A
- Authority
- PH
- Philippines
- Prior art keywords
- imidazol
- ylmethyl
- novel
- benzimidazole derivatives
- substituted benzimidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90790386A | 1986-09-15 | 1986-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
PH25022A true PH25022A (en) | 1991-01-28 |
Family
ID=25424835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH35811A PH25022A (en) | 1986-09-15 | 1987-09-14 | Novel (1h-imidazol-1-ylmethyl) substituted benzimidazole derivatives |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0260744B1 (ko) |
JP (1) | JPS6485975A (ko) |
KR (1) | KR960014353B1 (ko) |
CN (1) | CN1020903C (ko) |
AU (1) | AU595064B2 (ko) |
BG (1) | BG61321B2 (ko) |
CA (1) | CA1323366C (ko) |
CY (1) | CY1803A (ko) |
DE (1) | DE3783107T2 (ko) |
DK (1) | DK174728B1 (ko) |
ES (1) | ES2053524T3 (ko) |
FI (1) | FI87781C (ko) |
GR (1) | GR3006841T3 (ko) |
HK (1) | HK123694A (ko) |
HU (1) | HU198039B (ko) |
IE (1) | IE60514B1 (ko) |
IL (1) | IL83892A (ko) |
NO (1) | NO167202C (ko) |
NZ (1) | NZ221729A (ko) |
PH (1) | PH25022A (ko) |
PT (1) | PT85692B (ko) |
SU (1) | SU1662350A3 (ko) |
ZA (1) | ZA876881B (ko) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4826862A (en) * | 1988-02-12 | 1989-05-02 | Janssen Pharmaceutica, N.V. | Anthelminthic [(5(6) (1H-azole-1-ylmethyl)benzimidazole]carbamates |
GB8827820D0 (en) * | 1988-11-29 | 1988-12-29 | Janssen Pharmaceutica Nv | (1h-azol-1-ylmethyl)substituted quinoline derivatives |
CA2002864C (en) * | 1988-11-29 | 1999-11-16 | Eddy J. E. Freyne | (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives |
CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
FR2643903A1 (fr) * | 1989-03-03 | 1990-09-07 | Union Pharma Scient Appl | Nouveaux derives de benzimidazole, leurs procedes de preparation, intermediaires de synthese, compositions pharmaceutiques les contenant, utiles notamment pour le traitement des maladies cardiovasculaires, et des ulceres duodenaux |
PT95899A (pt) * | 1989-11-17 | 1991-09-13 | Glaxo Group Ltd | Processo para a preparacao de derivados indole |
US5021448A (en) * | 1990-02-22 | 1991-06-04 | Ciba-Geigy Corporation | Method of reducing serum uric acid and/or increasing renal uric acid clearance with thromboxane synthetase inhibitor inhibitor and/or thromboxane receptor antagonist |
FR2663028B1 (fr) * | 1990-06-08 | 1994-10-14 | Roussel Uclaf | Nouveaux derives de benzimidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
US5216003A (en) * | 1992-01-02 | 1993-06-01 | G. D. Searle & Co. | Diacid-containing benzimidazole compounds for treatment of neurotoxic injury |
WO1995004723A1 (fr) * | 1993-08-04 | 1995-02-16 | Yamanouchi Pharmaceutical Co., Ltd. | Derive d'imidazolylalkylamine et composition pharmaceutique contenant ledit derive |
HUT75871A (en) * | 1993-09-30 | 1997-05-28 | Yamanouchi Co | Azole derivatives and pharmaceutical compositions thereof |
NZ279227A (en) * | 1994-02-18 | 1997-11-24 | Janssen Pharmaceutica Nv | Dextrorotatory (+)-5-[3-chlorophenyl]-1h-imidazol-1-ylmethyl]-1h-benzimidazole derivatives (liarozole) |
JPH09508915A (ja) * | 1994-02-18 | 1997-09-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フェンノートシヤツプ | 鏡像異性体的に純粋な(−)−リアロゾール |
GB9418443D0 (en) * | 1994-09-13 | 1994-11-02 | Pfizer Ltd | Therapeutic agents |
US6696459B1 (en) | 1994-12-22 | 2004-02-24 | Ligand Pharmaceuticals Inc. | Steroid receptor modulator compounds and methods |
US5688808A (en) * | 1994-12-22 | 1997-11-18 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
DK0800519T3 (da) * | 1994-12-22 | 2004-03-01 | Ligand Pharm Inc | Steroidreceptormodulatorforbindelser og fremgangsmåder |
TW316902B (ko) * | 1994-12-28 | 1997-10-01 | Janssen Pharmaceutica Nv | |
EP0820989A4 (en) * | 1995-03-01 | 1998-05-06 | Yamanouchi Pharma Co Ltd | IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION BASED ON SAID DERIVATIVES |
US6288100B1 (en) * | 1995-06-06 | 2001-09-11 | American Home Products Corporation | Benzimidazole derivatives |
DE19535500A1 (de) * | 1995-09-25 | 1997-03-27 | Bayer Ag | Verfahren zur Herstellung von 3-Chlor-3'-nitro-4'-methoxybenzophenon |
DK0882718T3 (da) * | 1995-12-28 | 2005-12-12 | Astellas Pharma Inc | Benzimidazolderivater |
BR9710002A (pt) | 1996-06-27 | 1999-08-10 | Janssen Pharmaceutica Nv | N-[4-(heteroarilmetil)fenil]-heteroarilaminas |
FR2751649B1 (fr) * | 1996-07-26 | 1998-08-28 | Adir | Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
IT1286866B1 (it) * | 1996-10-28 | 1998-07-17 | Menarini Farma Ind | Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi |
ATE231128T1 (de) | 1997-02-21 | 2003-02-15 | Takeda Chemical Industries Ltd | Verbindungen mit kondensierten ringen, verfahren zu ihrer herstellung und ihre anwendung |
TW453999B (en) | 1997-06-27 | 2001-09-11 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
HUP0100860A3 (en) * | 1997-12-11 | 2003-03-28 | Janssen Pharmaceutica Nv | Retinoic acid mimetic anilides, process for their preparation and pharmaceutical compositions containing them |
DE19831985A1 (de) | 1998-07-16 | 2000-01-20 | Bayer Ag | Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen |
US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
US6858598B1 (en) | 1998-12-23 | 2005-02-22 | G. D. Searle & Co. | Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
EP1189889B1 (en) * | 1999-06-04 | 2003-12-17 | Elan Pharma International Limited | Compositions and methods for inhibiting cell death |
WO2001068591A1 (en) | 2000-03-16 | 2001-09-20 | F. Hoffmann-La Roche Ag | Carboxylic acid derivatives as ip antagonists |
CN1329394C (zh) | 2000-11-17 | 2007-08-01 | 武田药品工业株式会社 | 新咪唑衍生物、其制备方法及其用途 |
US6960586B2 (en) | 2000-11-20 | 2005-11-01 | Takeda Pharmaceutical Company Limited | Imidazole derivatives, process for their preparation and their use |
ATE440096T1 (de) | 2000-12-08 | 2009-09-15 | Takeda Pharmaceutical | Substituierte thiazolderivate mit 3- pyridylgruppen, verfahren zu deren herstellung und deren verwendung |
US7405235B2 (en) | 2001-05-04 | 2008-07-29 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
US6492517B1 (en) | 2001-07-19 | 2002-12-10 | Air Products And Chemicals, Inc. | Method for preparing halomethyl heterocyclic compounds |
JP4634037B2 (ja) * | 2001-11-16 | 2011-02-16 | 日本ケミファ株式会社 | キサンチンオキシダーゼ阻害剤 |
CA2504448C (en) * | 2002-11-01 | 2012-06-19 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
EP1654221A2 (en) * | 2003-06-10 | 2006-05-10 | Smithkline Beecham Corporation | Aniline derivatived androgen-, glucocorticoid-, mineralcorticoid- and progesterone- receptor modulators |
FR2860235A1 (fr) * | 2003-09-29 | 2005-04-01 | Yang Ji Chemical Company Ltd | Utilisation d'un compose de formule (i) inhibiteur de l'aromatase a des fins therapeutiques et composes de formule (i) en tant que tels |
AU2005324492B2 (en) | 2004-04-23 | 2012-06-07 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
CN101065363B (zh) * | 2004-09-30 | 2012-05-02 | 詹森药业有限公司 | 可用作选择性雄激素受体调节剂(sarms)的新苯并咪唑衍生物 |
AU2005292317B2 (en) * | 2004-09-30 | 2011-09-08 | Janssen Pharmaceutica N.V. | Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms) |
NZ570539A (en) * | 2006-01-24 | 2011-07-29 | Janssen Pharmaceutica Nv | 2-substituted benzimidazoles as selective androgen receptor modulators (SARMS) |
AU2007215247B2 (en) * | 2006-02-10 | 2012-12-13 | Transtech Pharma, Llc | Benzazole derivatives, compositions, and methods of use as Aurora kinase inhibitors |
KR101307497B1 (ko) * | 2006-04-19 | 2013-09-11 | 주식회사 동진쎄미켐 | 디이미다졸계 화합물 및 이를 이용한 유기발광소자 |
CN100496308C (zh) * | 2006-06-02 | 2009-06-10 | 上海烟草(集团)公司 | 造纸法再造烟叶半逆流多级萃取工艺 |
EP1992228A1 (en) * | 2007-05-14 | 2008-11-19 | Bayer CropScience AG | Insecticidal substituted thiourea derivatives |
EP2162450B1 (en) * | 2007-05-23 | 2015-02-25 | Allergan, Inc. | ((bicylicheteroaryl) imidazolyl) methylheteroaryl compounds as adrenergic receptor agonists |
DE102009038950A1 (de) | 2009-08-26 | 2011-03-03 | Bayer Animal Health Gmbh | Neue antiparasitäre Kombination von Wirkstoffen |
US9394290B2 (en) * | 2010-10-21 | 2016-07-19 | Universitaet Des Saarlandes Campus Saarbruecken | Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases |
US9199975B2 (en) | 2011-09-30 | 2015-12-01 | Asana Biosciences, Llc | Biaryl imidazole derivatives for regulating CYP17 |
CA2850508A1 (en) * | 2011-09-30 | 2013-04-04 | Endo Pharmaceuticals Inc. | Imidazole derivatives as cyp17 inhibitors for the treatment of cancer |
KR101884447B1 (ko) * | 2015-07-06 | 2018-08-01 | 삼성에스디아이 주식회사 | 모노머, 유기막 조성물, 유기막, 및 패턴형성방법 |
CA3233464A1 (en) * | 2021-10-04 | 2023-04-13 | Bolt Biotherapeutics, Inc. | Asymmetric bis-benzimidazole sting agonist immunoconjugates and uses thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR75101B (ko) * | 1980-10-23 | 1984-07-13 | Pfizer | |
GB8307865D0 (en) * | 1983-03-22 | 1983-04-27 | Fujisawa Pharmaceutical Co | Benzimidazole derivatives |
EP0178413A1 (en) * | 1984-08-17 | 1986-04-23 | Beecham Group Plc | Benzimidazoles |
-
1987
- 1987-09-08 NZ NZ221729A patent/NZ221729A/xx unknown
- 1987-09-09 EP EP87201702A patent/EP0260744B1/en not_active Expired - Lifetime
- 1987-09-09 DE DE8787201702T patent/DE3783107T2/de not_active Expired - Lifetime
- 1987-09-09 ES ES87201702T patent/ES2053524T3/es not_active Expired - Lifetime
- 1987-09-09 CY CY180387A patent/CY1803A/xx unknown
- 1987-09-14 ZA ZA876881A patent/ZA876881B/xx unknown
- 1987-09-14 JP JP62228679A patent/JPS6485975A/ja active Granted
- 1987-09-14 PT PT85692A patent/PT85692B/pt unknown
- 1987-09-14 IE IE248787A patent/IE60514B1/en not_active IP Right Cessation
- 1987-09-14 HU HU874071A patent/HU198039B/hu unknown
- 1987-09-14 FI FI873977A patent/FI87781C/fi not_active IP Right Cessation
- 1987-09-14 AU AU78385/87A patent/AU595064B2/en not_active Expired
- 1987-09-14 PH PH35811A patent/PH25022A/en unknown
- 1987-09-14 SU SU874203300A patent/SU1662350A3/ru active
- 1987-09-14 DK DK198704794A patent/DK174728B1/da not_active IP Right Cessation
- 1987-09-14 IL IL83892A patent/IL83892A/xx not_active IP Right Cessation
- 1987-09-14 NO NO873840A patent/NO167202C/no unknown
- 1987-09-14 CA CA000546763A patent/CA1323366C/en not_active Expired - Lifetime
- 1987-09-15 CN CN87106423A patent/CN1020903C/zh not_active Expired - Lifetime
- 1987-09-15 KR KR1019870010180A patent/KR960014353B1/ko not_active IP Right Cessation
-
1993
- 1993-01-21 GR GR930400092T patent/GR3006841T3/el unknown
- 1993-07-15 BG BG097951A patent/BG61321B2/bg unknown
-
1994
- 1994-11-10 HK HK123694A patent/HK123694A/xx not_active IP Right Cessation
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