PH21995A - Antibiotic compounds, their composition and process for the preparation of said compound - Google Patents

Antibiotic compounds, their composition and process for the preparation of said compound

Info

Publication number
PH21995A
PH21995A PH32776A PH32776A PH21995A PH 21995 A PH21995 A PH 21995A PH 32776 A PH32776 A PH 32776A PH 32776 A PH32776 A PH 32776A PH 21995 A PH21995 A PH 21995A
Authority
PH
Philippines
Prior art keywords
compound
preparation
composition
antibiotic compounds
antibiotic
Prior art date
Application number
PH32776A
Other languages
English (en)
Inventor
Ward John Barrie
Noble Hazel Mary
Noble David
Porter Neil
Fletton Richard Alan
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848423278A external-priority patent/GB8423278D0/en
Priority claimed from GB848432519A external-priority patent/GB8432519D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PH21995A publication Critical patent/PH21995A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PH32776A 1984-09-14 1985-09-13 Antibiotic compounds, their composition and process for the preparation of said compound PH21995A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848423278A GB8423278D0 (en) 1984-09-14 1984-09-14 Antibiotic compounds
GB848432519A GB8432519D0 (en) 1984-12-21 1984-12-21 Antibiotic compounds

Publications (1)

Publication Number Publication Date
PH21995A true PH21995A (en) 1988-05-02

Family

ID=26288220

Family Applications (2)

Application Number Title Priority Date Filing Date
PH32776A PH21995A (en) 1984-09-14 1985-09-13 Antibiotic compounds, their composition and process for the preparation of said compound
PH35113A PH24247A (en) 1984-09-14 1985-11-22 A method of combating parasitic or fungal conditions using macrolides antibiotic compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH35113A PH24247A (en) 1984-09-14 1985-11-22 A method of combating parasitic or fungal conditions using macrolides antibiotic compounds

Country Status (33)

Country Link
US (2) US4898821A (es)
JP (2) JPH07116199B2 (es)
KR (1) KR940004098B1 (es)
AT (1) AT396250B (es)
AU (1) AU596565B2 (es)
BE (1) BE903232A (es)
BG (1) BG44205A3 (es)
BR (1) BR8504457A (es)
CA (1) CA1313155C (es)
CH (1) CH666690A5 (es)
CS (1) CS268803B2 (es)
DE (1) DE3532794A1 (es)
DK (1) DK162099C (es)
ES (2) ES8704545A1 (es)
FI (1) FI87366C (es)
FR (1) FR2570390B1 (es)
GB (1) GB2166436B (es)
GR (1) GR852232B (es)
HU (1) HU197046B (es)
IE (1) IE59394B1 (es)
IL (1) IL76385A (es)
IT (1) IT1182857B (es)
LU (1) LU86074A1 (es)
NL (1) NL8502511A (es)
NZ (1) NZ213463A (es)
PH (2) PH21995A (es)
PL (1) PL152148B1 (es)
PT (1) PT81125B (es)
RO (1) RO92478A (es)
SE (2) SE502748C2 (es)
SU (1) SU1738090A3 (es)
UA (1) UA19162A (es)
ZW (1) ZW15585A1 (es)

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US4696922A (en) * 1984-11-26 1987-09-29 Ciba-Geigy Corporation 5-azolylacetoxymilbemycins as ecto- and endoparasites
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541
AT399441B (de) * 1985-04-30 1995-05-26 American Cyanamid Co Schädlingsbekämpfungsmittel und verfahren zur bekämpfung von schädlingen
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
DE3650265T2 (de) * 1985-09-13 1995-07-27 American Cyanamid Co Makrolide Antibiotika und Verfahren zu deren Herstellung.
GB8606116D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
AT398312B (de) * 1986-03-12 1994-11-25 American Cyanamid Co Verfahren zur herstellung einer neuen makroliden verbindung
GB8606105D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
PH24180A (en) * 1986-03-12 1990-03-22 Glaxo Group Ltd Macrolide compounds,pharmaceutical composition containing said compound and method of use thereof
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
PH27415A (en) * 1986-03-12 1993-06-21 American Cyanamid Co Macrolide compounds
GB8613790D0 (en) * 1986-06-06 1986-07-09 Glaxo Group Ltd Chemical compounds
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
NZ221077A (en) * 1986-07-18 1990-06-26 Ciba Geigy Ag 13b-alkyl milbemycins and use as parasiticides
EP0254583B1 (en) * 1986-07-24 1994-09-07 Beecham Group Plc Parasiticidal milbemycin derivatives, a process for their production, and compositions containing the same
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US5019589A (en) * 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
EP0259779B1 (en) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
EP0262384B1 (en) * 1986-09-12 1992-11-04 American Cyanamid Company 23-deoxy derivatives of ll-f28249 compounds
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5183749A (en) * 1987-02-04 1993-02-02 Sankyo Company, Ltd. Microbial process for the preparation of milbemycin derivatives
US4897416A (en) * 1987-02-18 1990-01-30 Ciba-Geigy Corporation Insecticides and parasiticides
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4876272A (en) * 1987-03-06 1989-10-24 American Cyanamid Company Mono- and diepoxide derivatives of LL-F28249 compounds
US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4851428A (en) * 1987-03-06 1989-07-25 American Cyanamid Company Mono- and diepoxide derivatives of Δ22-LL-F28249 compounds
US4855317A (en) * 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4871719A (en) * 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
GB8721378D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721375D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical process
GB8721377D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
GB8721647D0 (en) * 1987-09-15 1987-10-21 Pfizer Ltd Antiparasitic agents
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
ATE87926T1 (de) * 1987-11-09 1993-04-15 Pfizer Ethylierte avermectine.
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8803836D0 (en) * 1988-02-18 1988-03-16 Glaxo Group Ltd Compositions
GB8804440D0 (en) * 1988-02-25 1988-03-23 Pfizer Ltd Antiparasitic agents
GB8805978D0 (en) * 1988-03-14 1988-04-13 Glaxo Group Ltd Process
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
NZ232422A (en) * 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
US5322692A (en) * 1989-02-28 1994-06-21 American Cyanamid Company Sustained release bolus effective for the prolonged prevention, treatment or control of nematode, acarid and endo- and ectoparasitic infestations of ruminants
ES2052173T3 (es) * 1989-04-11 1994-07-01 Pfizer Composiciones inyectables que contienen 25-cyclohexil-avermectina b1.
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
ATE137745T1 (de) 1989-08-11 1996-05-15 American Cyanamid Co Arylpyrrol enthaltende insekticidale, acaricidale und nematicidale mittel sowie verfahren zu ihrer herstellung
NZ234802A (en) * 1989-08-14 1992-11-25 Merck & Co Inc Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5262400A (en) * 1991-06-20 1993-11-16 Merck & Co., Inc. 4α-substituted avermectin derivatives
MD24B1 (ro) * 1991-07-09 1994-05-31 Parfumerii Si Cosmetice Vioric Compozitie de substante odorante
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
US6486195B1 (en) * 1993-08-19 2002-11-26 Merck & Co., Inc. Thermodynamically stable crystal form of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation
JP2855181B2 (ja) 1993-12-10 1999-02-10 敏雄 鈴木 松類の枯損防止用組成物及び防止方法
WO1999017760A2 (en) 1997-10-02 1999-04-15 Microcide Pharmaceuticals, Inc. Fungal or mammalian cell efflux pump inhibitors for enhancing susceptibility of the cell to a drug
DE60118132T2 (de) 2000-10-10 2006-10-19 Wyeth Anthelmintika
GB0205253D0 (en) * 2002-03-06 2002-04-17 Univ Gent Immediate release pharmaceutical granule compositions and a continuous process for making them
US20080299212A1 (en) * 2005-02-25 2008-12-04 Medigenes Co., Ltd Pharmaceutical Composition for Treating Avellino Cornea Dystrophy Comprising Blood Plasma or Serum
CN100394983C (zh) * 2006-01-09 2008-06-18 浙江海正药业股份有限公司 含有大豆油的多拉菌素注射液

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SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4173571A (en) * 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
PT80577B (pt) * 1984-06-05 1987-09-18 American Cyanamid Co Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina

Also Published As

Publication number Publication date
KR940004098B1 (ko) 1994-05-13
US4935531A (en) 1990-06-19
AU4742685A (en) 1986-03-20
ES557237A0 (es) 1988-08-01
DK162099B (da) 1991-09-16
SE502748C2 (sv) 1995-12-18
IL76385A (en) 1990-09-17
DK418085A (da) 1986-03-15
FI853520A0 (fi) 1985-09-13
DK418085D0 (da) 1985-09-13
JP2566385B2 (ja) 1996-12-25
PL255360A1 (en) 1988-02-18
SU1738090A3 (ru) 1992-05-30
RO92478A (ro) 1987-09-30
SE469173B (sv) 1993-05-24
SE8802985D0 (sv) 1988-08-25
ES546962A0 (es) 1987-04-01
ES8802555A1 (es) 1988-08-01
DE3532794A1 (de) 1986-04-17
IT8548551A0 (it) 1985-09-13
HU197046B (en) 1989-02-28
NZ213463A (en) 1993-04-28
LU86074A1 (fr) 1986-04-03
US4898821A (en) 1990-02-06
AU596565B2 (en) 1990-05-10
IE59394B1 (en) 1994-02-23
DK162099C (da) 1992-02-24
UA19162A (uk) 1997-12-25
KR860002576A (ko) 1986-04-26
PH24247A (en) 1990-05-04
FR2570390B1 (fr) 1987-11-27
ES8704545A1 (es) 1987-04-01
BG44205A3 (en) 1988-10-14
GR852232B (es) 1986-01-14
CS268803B2 (en) 1990-04-11
PL152148B1 (en) 1990-11-30
IL76385A0 (en) 1986-01-31
JPH07213278A (ja) 1995-08-15
HUT39779A (en) 1986-10-29
ZW15585A1 (en) 1986-04-23
GB8522699D0 (en) 1985-10-16
CA1313155C (en) 1993-01-26
FI853520L (fi) 1986-03-15
BR8504457A (pt) 1986-07-15
GB2166436A (en) 1986-05-08
IE852263L (en) 1986-03-14
AT396250B (de) 1993-07-26
BE903232A (fr) 1986-03-13
CH666690A5 (de) 1988-08-15
FR2570390A1 (fr) 1986-03-21
IT1182857B (it) 1987-10-05
NL8502511A (nl) 1986-04-01
FI87366C (fi) 1992-12-28
GB2166436B (en) 1989-05-24
SE8504254D0 (sv) 1985-09-13
JPS61118387A (ja) 1986-06-05
JPH07116199B2 (ja) 1995-12-13
ATA268485A (de) 1992-11-15
FI87366B (fi) 1992-09-15
PT81125A (en) 1985-10-01
SE8504254L (sv) 1986-03-15
CS654685A2 (en) 1989-08-14
SE8802985L (sv) 1988-08-25
PT81125B (pt) 1987-10-20

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