PH14298A - 5-or 6-pyridazinyl-benimidazoles and salts thereof - Google Patents

5-or 6-pyridazinyl-benimidazoles and salts thereof

Info

Publication number
PH14298A
PH14298A PH17237A PH17237A PH14298A PH 14298 A PH14298 A PH 14298A PH 17237 A PH17237 A PH 17237A PH 17237 A PH17237 A PH 17237A PH 14298 A PH14298 A PH 14298A
Authority
PH
Philippines
Prior art keywords
benimidazoles
pyridazinyl
salts
Prior art date
Application number
PH17237A
Other languages
English (en)
Inventor
J Heider
V Austel
R Kadatz
E Kutter
W Eberlein
W Diederen
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742427943 external-priority patent/DE2427943C2/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of PH14298A publication Critical patent/PH14298A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH17237A 1974-06-10 1975-06-05 5-or 6-pyridazinyl-benimidazoles and salts thereof PH14298A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742427943 DE2427943C2 (de) 1974-06-10 1974-06-10 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2516040A DE2516040C2 (de) 1974-06-10 1975-04-12 Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
PH14298A true PH14298A (en) 1981-05-19

Family

ID=25767253

Family Applications (1)

Application Number Title Priority Date Filing Date
PH17237A PH14298A (en) 1974-06-10 1975-06-05 5-or 6-pyridazinyl-benimidazoles and salts thereof

Country Status (23)

Country Link
US (1) US4026891A (en:Method)
JP (1) JPS6015632B2 (en:Method)
AT (1) AT342610B (en:Method)
BE (1) BE830030A (en:Method)
BG (2) BG23216A3 (en:Method)
CA (1) CA1041095A (en:Method)
CH (1) CH620438A5 (en:Method)
CS (1) CS195292B2 (en:Method)
DD (1) DD120440A5 (en:Method)
DE (1) DE2516040C2 (en:Method)
DK (1) DK258975A (en:Method)
ES (2) ES437296A1 (en:Method)
FI (1) FI59408C (en:Method)
FR (1) FR2273545A1 (en:Method)
GB (1) GB1466547A (en:Method)
HU (1) HU171059B (en:Method)
IE (1) IE41257B1 (en:Method)
IL (1) IL47445A (en:Method)
NL (1) NL178969C (en:Method)
NO (1) NO142402C (en:Method)
PH (1) PH14298A (en:Method)
RO (1) RO68750A (en:Method)
SE (1) SE420836B (en:Method)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53117215A (en) * 1977-03-24 1978-10-13 Hideyoshi Morita Earthquakeeproof steel beam
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
US4258185A (en) * 1978-10-17 1981-03-24 Yoshitomi Pharmaceutical Industries, Ltd. Pyridazinone compounds
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3006671A1 (de) * 1980-02-22 1981-08-27 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzoxazole, deren herstellung und deren verwendung als arzneumittel
US4699909A (en) * 1981-07-25 1987-10-13 Dr. Karl Thomae Gmbh Benzotriazolyl-4,5-dihydro-3(2H)-pyridazinones
DE3129447A1 (de) * 1981-07-25 1983-02-10 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benztriazole, ihre herstellung und ihre verwendung als arzneimittel"
ZA859091B (en) * 1984-12-24 1987-07-29 Warner Lambert Co Novel 6-substituted-2 (1h)-quinolinones and related compounds having use as cardiotonic,anti-hypertensive,and anti-thrombotic agents
US4840955A (en) * 1984-12-24 1989-06-20 Warner-Lambert Company 6-substituted-2(1H)-quinolinones and related compounds having use as cardiotonic, antihypertensive, and antithrombotic agents
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4725686A (en) * 1985-11-22 1988-02-16 William H. Rorer, Inc. Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US4785101A (en) * 1985-11-22 1988-11-15 Rorer Pharmaceutical Corporation Benzodiazinone-hydroxypyrazolyl compounds, cardiotonic compositions including the same and their uses
US4868300A (en) * 1985-11-22 1989-09-19 Rorer Pharmaceutical Corporation Benzodiazinone-pyridazinone and hydroxy-pyrazolyl compounds, cardiotonic compositions including the same, and their uses
US5002944A (en) * 1986-10-29 1991-03-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having cardiotonic activity
US4859672A (en) * 1986-10-29 1989-08-22 Rorer Pharmaceutical Corporation Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone
JPS63181827U (en:Method) * 1987-05-13 1988-11-24
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
US6162804A (en) * 1997-09-26 2000-12-19 Merck & Co., Inc. Tyrosine kinase inhibitors
US6465484B1 (en) 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
ATE264104T1 (de) * 1998-10-23 2004-04-15 Toray Industries Immunmodulierende arzneimittelzusammenstellung
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
US20030236259A1 (en) * 2002-02-05 2003-12-25 Rolf Hohlweg Novel aryl- and heteroarylpiperazines
AU2005286793A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes
AU2005286728A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
US8071603B2 (en) * 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
EP1814551A2 (en) 2004-09-20 2007-08-08 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
US7767677B2 (en) 2004-09-20 2010-08-03 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
MX2007003329A (es) * 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y biciclicos y su uso como inhibidores de estearoil-coa-desaturasa (scd).
CA2580762A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
CA2580857A1 (en) * 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP4714921B2 (ja) * 2005-02-14 2011-07-06 トーアエイヨー株式会社 ピモベンダンの製造法及びその中間体
MX2007015216A (es) * 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Derivados de aminotiazol y sus usos como agentes terapeuticos.
US8501739B2 (en) 2005-07-04 2013-08-06 High Point Pharmaceuticals, Llc Medicaments
KR20080035700A (ko) * 2005-08-15 2008-04-23 아이알엠 엘엘씨 Ｔｐｏ 모방체로서의 화합물 및 조성물
AU2007267197B2 (en) * 2006-05-29 2011-12-01 High Point Pharmaceuticals, Llc 3- (1, 3-Benzodioxol-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine H3 receptor antagonist
EP2014656A3 (en) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC New heteocyclic h3 antagonists
AU2010226826A1 (en) 2009-03-18 2011-10-13 Merck Sharp & Dohme Corp. Bicyclic compounds as inhibitors of diacylglycerol acyltransferase
US8729263B2 (en) 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
CN105636953B (zh) * 2013-07-31 2018-01-02 诺华股份有限公司 1,4‑二取代的哒嗪衍生物及其用于治疗与smn缺乏相关的病症的用途
WO2018086703A1 (en) * 2016-11-11 2018-05-17 Bayer Pharma Aktiengesellschaft Dihydropyridazinones substituted with phenylureas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US3705157A (en) * 1970-10-19 1972-12-05 American Cyanamid Co Azolylpyridazine compounds and quaternary salts thereof
US3935209A (en) * 1973-03-12 1976-01-27 Syntex (U.S.A.) Inc. 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles

Also Published As

Publication number Publication date
NL7506806A (nl) 1975-12-12
AU8192675A (en) 1976-12-16
ATA344575A (de) 1977-08-15
IL47445A (en) 1978-07-31
DK258975A (da) 1975-12-11
DD120440A5 (en:Method) 1976-06-12
FR2273545A1 (fr) 1976-01-02
ES441340A1 (es) 1977-03-16
JPS516980A (en:Method) 1976-01-20
FI59408B (fi) 1981-04-30
DE2516040C2 (de) 1984-12-20
ES437296A1 (es) 1977-01-01
IE41257B1 (en) 1979-11-21
CS195292B2 (en) 1980-01-31
NL178969C (nl) 1986-06-16
NO752022L (en:Method) 1975-12-11
DE2516040A1 (de) 1976-11-04
GB1466547A (en) 1977-03-09
BG24052A3 (bg) 1977-12-15
SE7506583L (sv) 1975-12-11
RO68750A (ro) 1980-03-15
FI59408C (fi) 1981-08-10
AT342610B (de) 1978-04-10
CA1041095A (en) 1978-10-24
HU171059B (hu) 1977-10-28
US4026891A (en) 1977-05-31
BG23216A3 (bg) 1977-07-12
NO142402C (no) 1980-08-13
CH620438A5 (en:Method) 1980-11-28
JPS6015632B2 (ja) 1985-04-20
IL47445A0 (en) 1975-08-31
FI751700A7 (en:Method) 1975-12-11
SE420836B (sv) 1981-11-02
NO142402B (no) 1980-05-05
BE830030A (fr) 1975-12-09
FR2273545B1 (en:Method) 1979-08-10
IE41257L (en) 1975-12-10

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