PE25798A1 - Formulaciones de quinolona inyectables - Google Patents

Formulaciones de quinolona inyectables

Info

Publication number
PE25798A1
PE25798A1 PE1996000892A PE00089296A PE25798A1 PE 25798 A1 PE25798 A1 PE 25798A1 PE 1996000892 A PE1996000892 A PE 1996000892A PE 00089296 A PE00089296 A PE 00089296A PE 25798 A1 PE25798 A1 PE 25798A1
Authority
PE
Peru
Prior art keywords
injectable
pirrolidone
solvent
components
quinolone
Prior art date
Application number
PE1996000892A
Other languages
English (en)
Inventor
Wayne Alan Boettner
Peter Connor Canning
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21735307&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE25798(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of PE25798A1 publication Critical patent/PE25798A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

SE REFIEREN A LAS SOLUCIONES PARENTERALES, QUE COMPRENDEN: A) DANOFLOXACINA, PREFERENTEMENTE EN FORMA DE SAL DE MESILATO; B) UN COMPUESTO DE MAGNESIO, TAL COMO: MgO o MgCl, o DE CINC; C) UN DISOLVENTE COMPLEMENTARIO, QUE COMPRENDE AL MENOS UNO DE 2-PIRROLIDONA, PROPILENGLICOL, POLIETILENGLICOL Y N-METILPIRROLIDONA, OPCIONALMENTE JUNTO CON POLIVINILPIRROLIDONA; D) UN ANTIOXIDANTE, TAL COMO FORMALDEHIDO SULFOXILATO SODICO; E) COMPONENTES PARA AJUSTAR EL pH DE 5 A 9,5. SE POSTULA QUE LA INCORPORACION DE LOS COMPONENTES METALICOS (B) Y EL DISOLVENTE (C), AUMENTA LA SOLUBILIDAD EN EL AGUA, LO QUE MEJORA LA TOLERANCIA EN EL SITIO DE INYECCION, SIENDO USADOS EN EN EL TRATAMIENTO DE LAS INFECCIONES BACTERIANAS EN EL GANADO
PE1996000892A 1995-12-21 1996-12-10 Formulaciones de quinolona inyectables PE25798A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US905295P 1995-12-21 1995-12-21

Publications (1)

Publication Number Publication Date
PE25798A1 true PE25798A1 (es) 1998-05-21

Family

ID=21735307

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1996000892A PE25798A1 (es) 1995-12-21 1996-12-10 Formulaciones de quinolona inyectables

Country Status (42)

Country Link
US (1) US5811130A (es)
EP (1) EP0868183B1 (es)
JP (1) JP3416145B2 (es)
KR (1) KR100402570B1 (es)
CN (1) CN1104899C (es)
AP (1) AP706A (es)
AR (1) AR005147A1 (es)
AT (1) ATE212551T1 (es)
AU (1) AU709474B2 (es)
BG (1) BG63933B1 (es)
BR (1) BR9612230A (es)
CA (1) CA2239352C (es)
CO (1) CO4480098A1 (es)
CZ (1) CZ293747B6 (es)
DE (1) DE69618987T2 (es)
DK (1) DK0868183T3 (es)
DZ (1) DZ2146A1 (es)
EG (1) EG24071A (es)
ES (1) ES2167609T3 (es)
GT (1) GT199600098A (es)
HR (1) HRP960607B1 (es)
HU (1) HU227918B1 (es)
IL (1) IL124454A (es)
IS (1) IS2010B (es)
MA (1) MA24035A1 (es)
MX (1) MX9805026A (es)
MY (1) MY117109A (es)
NO (1) NO315734B1 (es)
NZ (2) NZ501160A (es)
OA (1) OA10697A (es)
PE (1) PE25798A1 (es)
PL (1) PL186795B1 (es)
PT (1) PT868183E (es)
RS (1) RS49523B (es)
RU (1) RU2141827C1 (es)
SI (1) SI0868183T1 (es)
SK (1) SK284412B6 (es)
TN (1) TNSN96163A1 (es)
TW (1) TW449475B (es)
UA (1) UA56151C2 (es)
WO (1) WO1997023217A1 (es)
ZA (1) ZA9610780B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID21415A (id) * 1997-12-05 1999-06-10 Upjohn Co Senyawa-senyawa antibiotik magnesium quinolon
US6017948A (en) * 1998-10-30 2000-01-25 Supergen, Inc. Water-miscible pharmaceutical compositions
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon
EP1255565A1 (de) * 2000-01-13 2002-11-13 MERCK PATENT GmbH Pharmazeutische zubereitungen enthaltend 2-pyrrolidon als lösungsvermittler
EP1356809A4 (en) * 2000-12-28 2008-05-14 Takeda Pharmaceutical SUSTAINED RELEASE PREPARATIONS
EP1524997A1 (en) * 2002-06-26 2005-04-27 Pharmacia Corporation Stable liquid parenteral parecoxib formulation
CA2572167A1 (en) * 2004-07-02 2006-01-12 Daiichi Pharmaceutical Co., Ltd. Quinolone-containing medicinal composition
DK1901749T3 (en) * 2005-05-18 2016-10-24 Raptor Pharmaceuticals Inc Aerosolized fluoroquinolones AND USES THEREOF
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
FR2896416B1 (fr) 2006-01-24 2010-08-13 Vetoquinol Composition anti-infectieuse comprenant un compose de type pyrido (3,2,1-ij)-benzoxadiazine
MX2008010222A (es) * 2006-02-10 2008-10-17 Pari Pharma Gmbh Antibioticos nebulizados para terapia de inhalacion.
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
DE102006010642A1 (de) * 2006-03-08 2007-09-27 Bayer Healthcare Aktiengesellschaft Arzneimittelformulierungen, enthaltend Fluorchinolone
DE102006010643A1 (de) * 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
MX2007009796A (es) 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel conteniendo pirfenidona.
KR20110091510A (ko) 2008-10-07 2011-08-11 엠펙스 파마슈티컬즈, 인코포레이티드 약동학 개선을 위한 에어로졸 플루오로퀴놀론 제형
CA2739893C (en) 2008-10-07 2016-10-04 Mpex Pharmaceuticals, Inc. Inhalation of levofloxacin for reducing lung inflammation
RU2015130524A (ru) 2009-09-04 2018-12-21 Раптор Фармасьютикалз Инк. Применение левофлоксацина в форме аэрозоля для лечения муковисцидоза
MX2011007675A (es) 2011-07-19 2012-07-11 Cell Therapy And Technology S A De C V Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas.
MX346763B (es) 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.
MX356551B (es) 2012-08-23 2018-06-04 Grupo Medifarma S A De C V Star Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné.
CA2987879A1 (en) 2015-06-02 2016-12-08 Kyorin Pharmaceutical Co., Ltd. Aqueous drug
WO2016195020A1 (ja) 2015-06-02 2016-12-08 杏林製薬株式会社 水性液剤
CA2988092A1 (en) 2015-06-02 2016-12-08 Kyorin Pharmaceutical Co., Ltd. Aqueous liquid formulation
WO2018146194A1 (en) * 2017-02-13 2018-08-16 Bayer Animal Health Gmbh Liquid composition containing pradofloxacin
MX366086B (es) 2017-08-15 2019-06-27 Cell Therapy And Tech S A De C V Composicion topica semisolida conteniendo un agente antimicrobiano y pirfenidona para el tratamiento de daños cronicos de la piel.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3517709A1 (de) * 1985-01-05 1986-07-10 Bayer Ag Basische zubereitungen von chinoloncarbonsaeuren
JPS63188626A (ja) * 1987-01-30 1988-08-04 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸の可溶化方法
DE3902079A1 (de) * 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
CA2072366C (en) * 1989-12-29 2002-08-20 Laman A. Al-Razzak Carboxylic acid-metal ion-acid complexes
US5084276A (en) * 1990-01-05 1992-01-28 Abbott Laboratories Quinolone carboxylic acid compositions with polymeric additive to reduce vein irritation
DE69102900T3 (de) * 1990-02-14 1998-04-09 Takeda Chemical Industries Ltd Brausemischung, deren Herstellung sowie Verwendung.
FR2665635A1 (fr) * 1990-08-10 1992-02-14 Merck Sharp & Dohme Composition pharmaceutique fluide a base d'un complexe metallique et son procede de preparation.
US5082863A (en) * 1990-08-29 1992-01-21 Schering Corporation Pharmaceutical composition of florfenicol
US5235054A (en) * 1992-07-15 1993-08-10 Pfizer Inc. 3-carboxaldehyde substituted quinolines and naphthyridines
JPH0782141A (ja) * 1993-09-17 1995-03-28 Tanabe Seiyaku Co Ltd 動物用注射剤

Also Published As

Publication number Publication date
HUP9903726A3 (en) 2001-01-29
KR19990076617A (ko) 1999-10-15
ES2167609T3 (es) 2002-05-16
TNSN96163A1 (fr) 2005-03-15
IS2010B (is) 2005-05-13
JP3416145B2 (ja) 2003-06-16
DZ2146A1 (fr) 2002-10-23
HU227918B1 (en) 2012-06-28
CO4480098A1 (es) 1997-07-09
DE69618987T2 (de) 2002-11-21
AP706A (en) 1998-12-04
AU709474B2 (en) 1999-08-26
NO315734B1 (no) 2003-10-20
SK284412B6 (sk) 2005-03-04
NO982842L (no) 1998-06-19
MX9805026A (es) 1998-09-30
CZ193098A3 (cs) 1999-05-12
JPH11501331A (ja) 1999-02-02
BG102542A (en) 1999-06-30
NZ320545A (en) 2000-03-27
KR100402570B1 (ko) 2003-12-18
ATE212551T1 (de) 2002-02-15
PL328001A1 (en) 1999-01-04
TW449475B (en) 2001-08-11
CZ293747B6 (cs) 2004-07-14
BG63933B1 (bg) 2003-07-31
EG24071A (en) 2008-05-11
CA2239352A1 (en) 1997-07-03
IL124454A0 (en) 1998-12-06
CN1104899C (zh) 2003-04-09
HUP9903726A2 (hu) 2000-04-28
OA10697A (en) 2001-05-04
IL124454A (en) 2003-10-31
CA2239352C (en) 2002-06-04
HRP960607B1 (en) 2002-06-30
YU69096A (sh) 1999-06-15
DE69618987D1 (de) 2002-03-14
UA56151C2 (uk) 2003-05-15
SK80798A3 (en) 1999-09-10
BR9612230A (pt) 1999-07-13
EP0868183A1 (en) 1998-10-07
RS49523B (sr) 2006-10-27
US5811130A (en) 1998-09-22
HRP960607A2 (en) 1998-06-30
WO1997023217A1 (en) 1997-07-03
NZ501160A (en) 2001-10-26
SI0868183T1 (en) 2002-04-30
MY117109A (en) 2004-05-31
NO982842D0 (no) 1998-06-19
AU7328996A (en) 1997-07-17
GT199600098A (es) 1998-06-12
IS4755A (is) 1998-05-25
DK0868183T3 (da) 2002-03-25
ZA9610780B (en) 1998-06-22
PL186795B1 (pl) 2004-02-27
AR005147A1 (es) 1999-04-14
CN1205636A (zh) 1999-01-20
RU2141827C1 (ru) 1999-11-27
AP9600898A0 (en) 1997-01-31
PT868183E (pt) 2002-06-28
EP0868183B1 (en) 2002-01-30
MA24035A1 (fr) 1997-07-01

Similar Documents

Publication Publication Date Title
PE25798A1 (es) Formulaciones de quinolona inyectables
TR199901127T2 (xx) Antibakteriyel etkili 6-O-ikameli ketolitler.
ECSP066512A (es) Formulación y método de aripiprazol inyectable estéril de liberación controlada
EA200501098A1 (ru) Антибактериальные агенты
MX9300579A (es) Derivados de pirazol, procedimientos para la preparacion de los mismos y a las composiciones farmaceuticas que comprenden a los mismos.
DE69108928T2 (de) Spritze mit nadelschutzvorrichtung.
EA200000600A1 (ru) Новые производные эритромицинов
AR087051A2 (es) Una composicion inhibidora del virus de la hepatitis c y uso
EA200300050A1 (ru) Гликопептидфосфонатные производные
WO2009087474A3 (en) Agonists for antimicrobial peptide systems
EA199901016A1 (ru) 9-оксим-производные эритромицина
EA200100416A1 (ru) 13-членные азалиды и их применение в качестве антибиотических агентов
MX9705559A (es) Derivados de acido neuraminico, su preparacion y su uso en medicina.
ATE222115T1 (de) Verbesserung der antibakteriellen wirkung von oxazolidinon durch arginin derivate
EA199700160A1 (ru) Производные индола в качестве антагонистов eaa
JOP20190209A1 (ar) مركبات إيميدازو [ 4، 5-c ] كينولين-2-أون ديوترومية واستخدامها في علاج السرطان
ATE203246T1 (de) Dialkyltiacumicine
DK1007530T3 (da) 6-O-substituerede erythromycinforbindelser samt fremgangsmåde til fremstilling heraf
CO5170485A1 (es) Prodrogas de antibioticos
DE59200387D1 (de) Heterocyclisch substituierte Chinolylmethoxy-Phenylacetamide als Lipoxygenasehemmer.
EA199800675A1 (ru) Дифенилстильбены как пролекарства к ингибиторам циклооксигеназы(сох-2)
EA200001029A1 (ru) Производные гигромицина
AR021463A1 (es) Antibiotico de piridona con perfil de seguridad mejorado
MX2020002606A (es) Composiciones inyectables de acetato de medroxiprogesterona y metodos de uso.
ES2176258T3 (es) Uso de penciclovir en el tratamiento de la neuralgia post-herpeticas. a

Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed