PE20151089A1 - Piridin-2-amidas utiles como agonistas de cb2 - Google Patents

Piridin-2-amidas utiles como agonistas de cb2

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Publication number
PE20151089A1
PE20151089A1 PE2015000754A PE2015000754A PE20151089A1 PE 20151089 A1 PE20151089 A1 PE 20151089A1 PE 2015000754 A PE2015000754 A PE 2015000754A PE 2015000754 A PE2015000754 A PE 2015000754A PE 20151089 A1 PE20151089 A1 PE 20151089A1
Authority
PE
Peru
Prior art keywords
pyridin
agonists
amides useful
useful
amides
Prior art date
Application number
PE2015000754A
Other languages
English (en)
Inventor
Stefanie Bendels
Uwe Grether
Atsushi Kimbara
Matthias Nettekoven
Stephan Roever
Mark Rogers-Evans
Ernst Schaffter
Tanja Schulz-Gasch
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PE20151089A1 publication Critical patent/PE20151089A1/es

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Abstract

Referida a un derivado de piridin-2-amida de formula (I) en la que de R1 a R4 tienen los significados definidos en la descripcion y en las reivindicaciones. Dichos compuestos tienen actividad sobre los receptores canabinoides 2 y son utiles en el tratamiento del dolor, aterosclerosis, retinopatia diabetica, glaucoma, etc
PE2015000754A 2012-12-07 2013-12-04 Piridin-2-amidas utiles como agonistas de cb2 PE20151089A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12196032 2012-12-07

Publications (1)

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PE20151089A1 true PE20151089A1 (es) 2015-08-06

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PE2015000754A PE20151089A1 (es) 2012-12-07 2013-12-04 Piridin-2-amidas utiles como agonistas de cb2

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US (1) US9303012B2 (es)
EP (1) EP2928868B1 (es)
JP (1) JP6426619B2 (es)
KR (1) KR20150091080A (es)
CN (1) CN104854092B (es)
AR (1) AR093806A1 (es)
AU (1) AU2013354114B2 (es)
BR (1) BR112015009600A2 (es)
CA (1) CA2885987A1 (es)
CL (1) CL2015001538A1 (es)
CR (1) CR20150204A (es)
DK (1) DK2928868T3 (es)
EA (1) EA025841B1 (es)
ES (1) ES2643058T3 (es)
HK (1) HK1208033A1 (es)
HR (1) HRP20171445T1 (es)
IL (1) IL237988A (es)
LT (1) LT2928868T (es)
MA (2) MA40308A1 (es)
MX (1) MX2015007033A (es)
MY (1) MY182328A (es)
PE (1) PE20151089A1 (es)
PH (1) PH12015501073A1 (es)
PL (1) PL2928868T3 (es)
PT (1) PT2928868T (es)
RS (1) RS56423B1 (es)
SG (1) SG11201504122YA (es)
SI (1) SI2928868T1 (es)
TW (1) TWI617551B (es)
UA (1) UA114655C2 (es)
WO (1) WO2014086806A1 (es)
ZA (1) ZA201502872B (es)

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WO2014135507A1 (en) 2013-03-07 2014-09-12 F. Hoffmann-La Roche Ag Novel pyrazol derivatives
DK2978755T3 (en) 2013-03-26 2018-03-05 Hoffmann La Roche Hitherto unknown pyridine derivatives
CA2907691A1 (en) 2013-05-02 2014-11-06 F. Hoffmann-La Roche Ag Pyrrolo[2,3-d]pyrimidine derivatives as cb2 receptor agonists
KR20210145303A (ko) 2013-05-02 2021-12-01 에프. 호프만-라 로슈 아게 Cb2 수용체 작용제로서의 퓨린 유도체
JP6441356B2 (ja) 2013-09-06 2018-12-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 新規トリアゾロ［４，５−ｄ］ピリミジン誘導体
WO2015150438A1 (en) * 2014-04-04 2015-10-08 F. Hoffmann-La Roche Ag 5,6-disubstituted pyridine-2-carboxamides as cannabinoid receptor agonists
CA2943013A1 (en) * 2014-04-04 2015-10-08 F. Hoffmann-La Roche Ag Pyridine-2-amides useful as cb2 agonists
WO2016121959A1 (ja) * 2015-01-30 2016-08-04 富士フイルム株式会社 イソインドリン化合物またはその塩の製造方法および新規イソインドリン化合物またはその塩
CN116102449A (zh) 2015-12-09 2023-05-12 豪夫迈·罗氏有限公司 作为大麻素受体2激动剂的苯基衍生物
CN106187910A (zh) * 2016-07-07 2016-12-07 浙江大学 哒嗪类衍生物及其制备方法和用途
AR112199A1 (es) 2017-06-20 2019-10-02 Hoffmann La Roche Derivados de piridina como agonistas inversos del receptor cannabinoide 2
JP7454512B2 (ja) 2018-06-27 2024-03-22 エフ． ホフマン－ラ ロシュ アーゲー 優先的カンナビノイド２アゴニストとしてのピリジン及びピラジン誘導体
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