PE20090104A1 - Bacterias modificadas para incrementar la produccion de metabolitos derivados de acetil coenzima a - Google Patents

Bacterias modificadas para incrementar la produccion de metabolitos derivados de acetil coenzima a

Info

Publication number
PE20090104A1
PE20090104A1 PE2008001836A PE2008001836A PE20090104A1 PE 20090104 A1 PE20090104 A1 PE 20090104A1 PE 2008001836 A PE2008001836 A PE 2008001836A PE 2008001836 A PE2008001836 A PE 2008001836A PE 20090104 A1 PE20090104 A1 PE 20090104A1
Authority
PE
Peru
Prior art keywords
production
increase
acetyl coenzyme
metabolites derived
bacterium
Prior art date
Application number
PE2008001836A
Other languages
English (en)
Inventor
Yuri Ivanovich Kozlov
Akito Chinen
Hiroshi Izui
Yoshihiko Hara
Hisashi Yasueda
Konstantin Vyacheslavovich Rybak
Ekaterina Aleksandrovna Slivinskaya
Joanna Yosifovna Katashkina
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2004124226/13A external-priority patent/RU2004124226A/ru
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of PE20090104A1 publication Critical patent/PE20090104A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A BACTERIAS MODIFICADAS, CARACTERIZADAS POR: a)BACTERIAS CON INHERENTE ACTIVIDAD DE FOSFOCETOLASA DE D-XILULOSA-5-FOSFATO, FOSFOCETOLASA DE FRUCTOSA-6-FOSFATO O AMBAS, DONDE DICHA ACTIVIDAD ES MEJORADA MEDIANTE EL AUMENTO DE COPIAS DEL GEN CODIFICADOR O MODIFICANDO UNA SECUENCIA REGULADORA DE LA EXPRESION DEL GEN; Y b)BACTERIAS QUE NO TIENEN ACTIVIDAD FOSFOCETOLASA DE D-XILULOSA-5-FOSFATO Y FOSFOCETOLASA DE FRUCTOSA-6-FOSFATO, LAS CUALES SON TRANSFORMADAS CON UN FRAGMENTO DE ADN QUE CODIFICA PARA DICHA ACTIVIDAD. DICHAS BACTERIAS TIENEN CAPACIDAD DE PRODUCIR UN METABOLITO SELECCIONADO DE: L-ACIDO GLUTAMICO, L-GLUTAMINA, L-PROLINA Y L-LEUCINA
PE2008001836A 2004-08-10 2005-08-10 Bacterias modificadas para incrementar la produccion de metabolitos derivados de acetil coenzima a PE20090104A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2004124226/13A RU2004124226A (ru) 2004-08-10 2004-08-10 Использование фосфокетолазы для продукции полезных метаболитов
US64456205P 2005-01-19 2005-01-19

Publications (1)

Publication Number Publication Date
PE20090104A1 true PE20090104A1 (es) 2009-03-07

Family

ID=35106939

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2008001836A PE20090104A1 (es) 2004-08-10 2005-08-10 Bacterias modificadas para incrementar la produccion de metabolitos derivados de acetil coenzima a

Country Status (10)

Country Link
EP (1) EP1789547B1 (es)
JP (1) JP5596902B2 (es)
KR (2) KR100892577B1 (es)
AT (1) ATE463564T1 (es)
AU (1) AU2005272367B2 (es)
BR (1) BRPI0514201B1 (es)
DE (1) DE602005020469D1 (es)
ES (1) ES2341264T3 (es)
PE (1) PE20090104A1 (es)
WO (1) WO2006016705A1 (es)

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PE20071235A1 (es) * 2006-01-27 2007-12-02 Ajinomoto Kk Metodo para producir l-amino acidos
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2062967A1 (en) * 2007-11-21 2009-05-27 Technical University of Denmark Genetically engineered aspergillus
JP5520498B2 (ja) * 2009-02-24 2014-06-11 花王株式会社 タンパク質又はポリペプチドの製造方法
EP2666855B1 (en) * 2011-01-20 2017-11-22 Toyota Jidosha Kabushiki Kaisha Recombinant yeast and method for producing substance using same
DK2732031T3 (en) * 2011-07-12 2015-11-30 Scientist Of Fortune Sa Recombinant microorganism to produce useful metabolic products
SG11201401249PA (en) * 2011-10-07 2014-05-29 Danisco Us Inc Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
WO2013069634A1 (ja) 2011-11-11 2013-05-16 味の素株式会社 発酵法による目的物質の製造法
JP6530375B2 (ja) * 2013-04-10 2019-06-12 ダニスコ・ユーエス・インク アセチル補酵素ａ由来代謝産物、イソプレン、イソプレノイド前駆体、およびイソプレノイドの改善された生産のためのホスホケトラーゼ
KR101773755B1 (ko) 2013-05-13 2017-09-01 아지노모토 가부시키가이샤 Ｌ-아미노산의 제조법
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
KR101500847B1 (ko) * 2013-07-23 2015-03-16 씨제이제일제당 (주) 천연 코쿠미 조미소재의 제조 방법
KR101500848B1 (ko) * 2013-07-23 2015-03-09 씨제이제일제당 (주) 천연 뉴트럴 조미소재의 제조 방법
KR101500846B1 (ko) * 2013-07-23 2015-03-16 씨제이제일제당 (주) 천연 소고기 풍미 조미소재의 제조 방법
KR101500850B1 (ko) * 2013-08-07 2015-03-18 씨제이제일제당 (주) 천연 조미소재 제조를 위한 이노신산 발효액 또는 글루탐산 발효액의 제조 방법
CN104736707B (zh) 2013-10-21 2017-08-25 味之素株式会社 生产l‑氨基酸的方法
BR112016008830B1 (pt) 2013-10-23 2023-02-23 Ajinomoto Co., Inc Método para produzir uma substância alvo
EP3967747B1 (en) * 2013-12-03 2023-11-08 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
JP2017508473A (ja) * 2014-03-26 2017-03-30 サイエンティスト・オブ・フォーチュン・ソシエテ・アノニム ホルムアルデヒドからのアセチルリン酸の酵素的産生
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系ｌ−アミノ酸の製造法
US10428359B2 (en) 2016-10-03 2019-10-01 Ajinomoto Co, Inc. Method for producing L-amino acid
KR101812016B1 (ko) 2016-10-12 2017-12-26 단국대학교 천안캠퍼스 산학협력단 락토바실러스 존소니 유래의 산성 조건에서 발현이 증가되는 프로모터 및 이의 용도
EP3354742A1 (en) 2017-01-26 2018-08-01 Metabolic Explorer Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN109929883A (zh) * 2019-04-02 2019-06-25 烟台华康荣赞生物科技有限公司 重组酵母、构建方法和其在制备酪醇及衍生物中的应用
JP6917434B2 (ja) * 2019-10-25 2021-08-11 長瀬産業株式会社 好気性菌の代謝酵素破壊株およびその培養法
JPWO2022092018A1 (es) 2020-10-28 2022-05-05
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid

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Also Published As

Publication number Publication date
ATE463564T1 (de) 2010-04-15
BRPI0514201A (pt) 2008-06-03
ES2341264T3 (es) 2010-06-17
AU2005272367B2 (en) 2009-02-12
EP1789547B1 (en) 2010-04-07
DE602005020469D1 (de) 2010-05-20
KR20070043877A (ko) 2007-04-25
AU2005272367A1 (en) 2006-02-16
EP1789547A1 (en) 2007-05-30
JP5596902B2 (ja) 2014-09-24
KR20090010139A (ko) 2009-01-28
JP2008509661A (ja) 2008-04-03
WO2006016705A1 (en) 2006-02-16
KR100892577B1 (ko) 2009-04-08
BRPI0514201B1 (pt) 2020-09-15

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