PE20061165A1 - Bacteria corineforme mutada que produce l-aminoacidos - Google Patents

Bacteria corineforme mutada que produce l-aminoacidos

Info

Publication number
PE20061165A1
PE20061165A1 PE2005001375A PE2005001375A PE20061165A1 PE 20061165 A1 PE20061165 A1 PE 20061165A1 PE 2005001375 A PE2005001375 A PE 2005001375A PE 2005001375 A PE2005001375 A PE 2005001375A PE 20061165 A1 PE20061165 A1 PE 20061165A1
Authority
PE
Peru
Prior art keywords
amino acids
corineforme
mutated
bacteria producing
bacteria
Prior art date
Application number
PE2005001375A
Other languages
English (en)
Inventor
Keita Fukui
Jun Nakamura
Hiroyuki Koyima
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of PE20061165A1 publication Critical patent/PE20061165A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

SE REFIERE A UNA BACTERIA CORINEFORME CUYA ACTIVIDAD DE ACETIL-CoA HIDROLASA SE ENCUENTRA REDUCIDA INTRODUCIENDO UNA MUTACION EN UNA REGION REGULADORA DE EXPRESION DEL GEN DE ACETIL-CoA HIDROLASA CROMOSOMICO QUE COMPRENDE NUCLEOTIDOS 1037 A 2542 DE SEQ ID NO:23. DICHA BACTERIA PUEDE PRODUCIR L-AMINOACIDOS TAL COMO ACIDO L-GLUTAMICO, L-ARGININA, L-GLUTAMINA, L-PROLINA, L-ALANINA, L-VALINA Y L-LISINA
PE2005001375A 2004-11-25 2005-11-25 Bacteria corineforme mutada que produce l-aminoacidos PE20061165A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004340187A JP4595506B2 (ja) 2004-11-25 2004-11-25 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法

Publications (1)

Publication Number Publication Date
PE20061165A1 true PE20061165A1 (es) 2006-10-21

Family

ID=35945268

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005001375A PE20061165A1 (es) 2004-11-25 2005-11-25 Bacteria corineforme mutada que produce l-aminoacidos

Country Status (12)

Country Link
US (1) US8628941B2 (es)
EP (1) EP1814987B1 (es)
JP (1) JP4595506B2 (es)
KR (1) KR101186128B1 (es)
CN (2) CN102031238B (es)
AT (1) ATE526404T1 (es)
AU (1) AU2005308023B2 (es)
BR (1) BRPI0518589B1 (es)
ES (1) ES2375650T3 (es)
MY (1) MY141980A (es)
PE (1) PE20061165A1 (es)
WO (1) WO2006057450A1 (es)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1253195T3 (da) 2000-01-21 2009-01-12 Ajinomoto Kk Fremgangsmåde til fremstilling af L-lysin
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
US7794989B2 (en) * 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
JP2008283863A (ja) 2005-08-26 2008-11-27 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
WO2007086608A1 (en) 2006-01-27 2007-08-02 Ajinomoto Co., Inc. Method for producing l-amino acid
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2149607B1 (en) * 2007-04-10 2017-12-20 Ajinomoto Co., Inc. Method for production of succinic acid
JPWO2008133131A1 (ja) * 2007-04-16 2010-07-22 味の素株式会社 有機酸の製造方法
WO2008133161A1 (ja) 2007-04-17 2008-11-06 Ajinomoto Co., Inc. カルボキシル基を有する酸性物質の製造法
JP5644108B2 (ja) * 2007-12-06 2014-12-24 味の素株式会社 有機酸の製造方法
IN2014CN04002A (es) 2011-11-02 2015-10-23 Ajinomoto Kk
IN2014CN04039A (es) 2011-11-02 2015-10-23 Ajinomoto Kk
WO2013069634A1 (ja) 2011-11-11 2013-05-16 味の素株式会社 発酵法による目的物質の製造法
CN102634474B (zh) * 2012-03-31 2013-04-17 江南大学 一株嗜乙酰乙酸棒杆菌及其产丁二酸的方法
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
RU2573933C1 (ru) 2014-08-21 2016-01-27 Дафот Энтерпрайсис Лимитед Пептид для лечения сахарного диабета 2-го типа и его осложнений
KR101835935B1 (ko) 2014-10-13 2018-03-12 씨제이제일제당 (주) L-아르기닌을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌의 제조 방법
WO2016060437A1 (ko) * 2014-10-13 2016-04-21 씨제이제일제당 주식회사 L-아르기닌을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌의 제조 방법
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
KR101793328B1 (ko) * 2015-07-03 2017-11-03 씨제이제일제당 (주) Ｌ-라이신 생산능을 갖는 미생물 및 이를 이용한 ｌ-라이신 생산 방법
CN105063159B (zh) * 2015-09-19 2021-06-25 内蒙古阜丰生物科技有限公司 浓缩连续等电提取谷氨酸的新工艺
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系ｌ−アミノ酸の製造法
CN106367432B (zh) * 2016-09-01 2017-07-18 宁夏伊品生物科技股份有限公司 发酵生产l‑赖氨酸的方法及改造的棒杆菌
CA3035466C (en) 2016-09-01 2023-08-29 Ningxia Eppen Biotech Co., Ltd Corynebacterium for producing l-lysine by fermentation
KR102335301B1 (ko) 2016-10-21 2021-12-06 아지노모토 가부시키가이샤 단백질의 분비 생산법
EP3530747A4 (en) 2016-10-21 2020-07-22 Ajinomoto Co., Inc. SECRETORY PROTEIN PRODUCTION PROCESS
BR112019018859A2 (pt) 2017-03-28 2020-04-14 Ajinomoto Kk método para produzir rna objetivo
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
KR102008673B1 (ko) * 2017-12-07 2019-08-09 대상 주식회사 락토바실러스 퍼멘텀 c-7a 균주 및 이의 용도
KR101947945B1 (ko) * 2018-01-25 2019-02-13 씨제이제일제당 (주) L-아미노산을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아미노산의 생산방법
KR20210002575A (ko) 2018-04-20 2021-01-08 아지노모토 가부시키가이샤 단백질의 분비 생산법
EP3839051A1 (en) 2019-12-19 2021-06-23 Evonik Operations GmbH Method for the fermentative production of guanidinoacetic acid
KR102263091B1 (ko) * 2020-05-21 2021-06-09 씨제이제일제당 주식회사 L-분지쇄 아미노산 생산능이 강화된 미생물 및 이를 이용한 l-분지쇄 아미노산 생산방법
CN113832087B (zh) * 2020-06-23 2023-09-12 江南大学 一种利用大肠杆菌全生物合成丙二酸的方法
US20230235375A1 (en) 2020-06-23 2023-07-27 Dsm Ip Assets B.V. Fermentation process
WO2022092018A1 (ja) 2020-10-28 2022-05-05 味の素株式会社 Ｌ－アミノ酸の製造法
CN114540261B (zh) * 2020-11-24 2024-02-02 北京化工大学 一种产氨基己二酸的基因工程菌
KR102281364B1 (ko) * 2021-01-26 2021-07-22 씨제이제일제당 (주) 신규한 우레아제 부속 단백질 변이체 및 이를 이용한 l-발린 생산 방법
KR102281363B1 (ko) * 2021-01-26 2021-07-22 씨제이제일제당 (주) 신규한 시스테인 설피네이트 디설피나제 변이체 및 이를 이용한 l-발린 생산 방법
KR102281365B1 (ko) * 2021-01-26 2021-07-22 씨제이제일제당 (주) 신규한 프롤린 탈수소효소 변이체 및 이를 이용한 l-발린 생산 방법
CN112442475B (zh) * 2021-02-01 2021-04-30 天津科技大学 一种l-谷氨酸生产菌株及其构建方法与应用
KR102281370B1 (ko) * 2021-04-07 2021-07-22 씨제이제일제당 (주) 신규한 2-이소프로필말레이트합성효소 변이체 및 이를 이용한 l-발린 생산 방법
KR102306010B1 (ko) * 2021-04-07 2021-09-27 씨제이제일제당 (주) 신규한 분지쇄아미노산 투과효소 변이체 및 이를 이용한 l-발린 생산 방법
KR102281371B1 (ko) * 2021-04-07 2021-07-22 씨제이제일제당 (주) 신규한 글리세르알데히드-3-인산탈수소효소 변이체 및 이를 이용한 l-발린 생산 방법
WO2022231042A1 (ko) * 2021-04-30 2022-11-03 씨제이제일제당 (주) 신규한 변이체 및 이를 이용한 l-발린 생산 방법
CN116555138B (zh) * 2023-02-06 2024-02-13 森瑞斯生物科技(深圳)有限公司 乙酰辅酶a合成酶acs突变体及其在2-吡咯烷酮生产中的应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3783081T2 (de) * 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
JP2526836B2 (ja) 1991-08-23 1996-08-21 味の素株式会社 酢酸資化性遺伝子
JP3301140B2 (ja) * 1993-02-16 2002-07-15 味の素株式会社 発酵法によるｌ−グルタミン酸の製造法
JP2844511B2 (ja) 1993-09-02 1999-01-06 味の素株式会社 酢酸資化性遺伝子及びその利用
US5504004A (en) * 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
KR19990013007A (ko) 1997-07-31 1999-02-25 박원훈 형질전환된 대장균 ｓｓ373(ｋｃｔｃ 8818ｐ)과 이를 이용한숙신산의 생산방법
JP4197754B2 (ja) 1997-10-09 2008-12-17 三菱化学株式会社 乳酸又はコハク酸の製造方法
JP3967812B2 (ja) 1998-01-16 2007-08-29 三菱化学株式会社 ピルビン酸カルボキシラーゼ遺伝子組み換え菌体による有機酸の製造法
JP4074365B2 (ja) 1998-01-28 2008-04-09 三菱化学株式会社 ラクテートデヒドロゲナーゼ遺伝子及び該遺伝子破壊株
DE69941594D1 (de) * 1998-09-25 2009-12-10 Ajinomoto Kk Coryneforme bakterien zur herstellung von l-glu
DE19951975A1 (de) 1999-10-28 2001-05-03 Degussa Neue für das poxB-Gen codierende Nuleotidsequenzen
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
ATE274575T1 (de) 2000-09-30 2004-09-15 Degussa Prozess zur fermentativen herstellung von d- pantothensäure mit coryneformen bakterien
WO2002036797A2 (en) 2000-11-04 2002-05-10 Degussa Ag Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family
DE10112102A1 (de) 2001-03-14 2002-09-19 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure und/oder deren Salzen
DE10154175A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Homeostase-und Adaptions-Proteine codieren
AU2003205041A1 (en) * 2002-07-12 2004-01-29 Ajinomoto Co., Inc. Method for producing target substance by fermentation
BR0304860A (pt) * 2002-11-11 2004-08-31 Ajinomoto Kk Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia
EP1424397B1 (en) * 2002-11-26 2011-01-19 Ajinomoto Co., Inc. Method for producing L-glutamine and L-glutamine producing bacterium
EP1460128B1 (en) * 2003-03-03 2016-11-30 Ajinomoto Co., Inc. Method for producing L-arginine or L-lysine by fermentation
US7344874B2 (en) * 2004-03-04 2008-03-18 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US7205132B2 (en) * 2004-09-10 2007-04-17 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
JP4595506B2 (ja) 2004-11-25 2010-12-08 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
US7794989B2 (en) * 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid

Also Published As

Publication number Publication date
JP2006149214A (ja) 2006-06-15
CN102031238B (zh) 2013-01-30
AU2005308023B2 (en) 2010-06-24
CN101065484A (zh) 2007-10-31
US20070254345A1 (en) 2007-11-01
CN102031238A (zh) 2011-04-27
ATE526404T1 (de) 2011-10-15
BRPI0518589B1 (pt) 2021-04-27
AU2005308023A1 (en) 2006-06-01
BRPI0518589A2 (pt) 2008-11-25
JP4595506B2 (ja) 2010-12-08
US8628941B2 (en) 2014-01-14
ES2375650T3 (es) 2012-03-05
KR20070091303A (ko) 2007-09-10
MY141980A (en) 2010-08-16
WO2006057450A1 (en) 2006-06-01
KR101186128B1 (ko) 2012-09-27
CN101065484B (zh) 2011-03-02
EP1814987A1 (en) 2007-08-08
EP1814987B1 (en) 2011-09-28

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