PE20040895A1 - Formulacion de complejo de aripiprazol - Google Patents

Formulacion de complejo de aripiprazol

Info

Publication number
PE20040895A1
PE20040895A1 PE2003000843A PE2003000843A PE20040895A1 PE 20040895 A1 PE20040895 A1 PE 20040895A1 PE 2003000843 A PE2003000843 A PE 2003000843A PE 2003000843 A PE2003000843 A PE 2003000843A PE 20040895 A1 PE20040895 A1 PE 20040895A1
Authority
PE
Peru
Prior art keywords
aripiprazole
injection site
intramuscular injection
formulation
beta
Prior art date
Application number
PE2003000843A
Other languages
English (en)
Inventor
Manoj Nerurkar
Vijay Naringrekar
Mark Dominick
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31946748&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20040895(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PE20040895A1 publication Critical patent/PE20040895A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A UNA FORMULACION DE ARIPIPRAZOL QUE INCLUYE UN AGENTE ANTISICOTICO EN LA FORMA DE UN COMPLEJO DE INCLUSION EN UNA BETA-CICLODEXTRINA, PREFERIBLEMENTE BETA-CICLODEXTRINA DE ETER SULFOBUTILO (SBECD), QUE EN LA FORMA DE INYECTABLE PRODUCE GENERALMENTE IRRITACION REVERSIBLE MINIMA A MODERADA EN EL SITIO DE INYECCION INTRAMUSCULAR. SE PROPORCIONAN UN METODO PARA MINIMIZAR O REDUCIR LA IRRITACION CAUSADA POR EL ARIPIPRAZOL EN UN SITIO DE INYECCION INTRAMUSCULAR EN UN SITIO DE INYECCION INTRAMUSCULAR Y UN METODO PARA TRATAR ESQUIZOFRENIA MEDIANTE EL EMPLEO DE DICHA FORMULACION
PE2003000843A 2002-08-20 2003-08-20 Formulacion de complejo de aripiprazol PE20040895A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40471302P 2002-08-20 2002-08-20

Publications (1)

Publication Number Publication Date
PE20040895A1 true PE20040895A1 (es) 2004-11-20

Family

ID=31946748

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000843A PE20040895A1 (es) 2002-08-20 2003-08-20 Formulacion de complejo de aripiprazol

Country Status (32)

Country Link
US (8) US7115587B2 (es)
EP (1) EP1542668B1 (es)
JP (1) JP4729306B2 (es)
KR (1) KR101043866B1 (es)
CN (1) CN100335047C (es)
AR (2) AR040887A1 (es)
AT (1) ATE428423T1 (es)
AU (1) AU2003269965B2 (es)
BR (1) BR0313602A (es)
CA (1) CA2495864C (es)
CY (1) CY1110331T1 (es)
DE (1) DE60327225D1 (es)
DK (1) DK1542668T3 (es)
ES (1) ES2322953T3 (es)
GE (1) GEP20063996B (es)
HR (1) HRP20050149B1 (es)
IL (1) IL166623A (es)
IS (1) IS2878B (es)
MX (1) MXPA05001865A (es)
MY (1) MY140793A (es)
NO (1) NO333458B1 (es)
NZ (1) NZ537995A (es)
PE (1) PE20040895A1 (es)
PL (1) PL212428B1 (es)
PT (1) PT1542668E (es)
RS (1) RS51903B (es)
RU (1) RU2342931C2 (es)
SI (1) SI1542668T1 (es)
TW (1) TWI307626B (es)
UA (1) UA79984C2 (es)
WO (1) WO2004017897A2 (es)
ZA (1) ZA200501064B (es)

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Also Published As

Publication number Publication date
US20040077594A1 (en) 2004-04-22
IL166623A0 (en) 2006-01-15
US20150328335A1 (en) 2015-11-19
IS7701A (is) 2005-02-18
US20060234979A1 (en) 2006-10-19
IS2878B (is) 2014-04-15
CA2495864A1 (en) 2004-03-04
US20140235574A1 (en) 2014-08-21
ES2322953T3 (es) 2009-07-02
US20120053145A1 (en) 2012-03-01
RU2342931C2 (ru) 2009-01-10
RS20050118A (en) 2007-06-04
KR101043866B1 (ko) 2011-06-22
PL212428B1 (pl) 2012-09-28
TWI307626B (en) 2009-03-21
US20130045981A1 (en) 2013-02-21
RS51903B (sr) 2012-02-29
TW200405813A (en) 2004-04-16
BR0313602A (pt) 2005-06-21
US20110160224A1 (en) 2011-06-30
DK1542668T3 (da) 2009-07-20
US8999952B2 (en) 2015-04-07
MY140793A (en) 2010-01-15
AR102101A2 (es) 2017-02-01
CN1674882A (zh) 2005-09-28
AU2003269965B2 (en) 2008-02-21
NZ537995A (en) 2007-11-30
SI1542668T1 (sl) 2009-08-31
CA2495864C (en) 2011-09-27
CN100335047C (zh) 2007-09-05
KR20050040927A (ko) 2005-05-03
RU2005107471A (ru) 2005-09-10
JP2006501240A (ja) 2006-01-12
US7550445B2 (en) 2009-06-23
ZA200501064B (en) 2006-12-27
IL166623A (en) 2011-07-31
EP1542668A4 (en) 2007-10-17
WO2004017897A3 (en) 2004-12-02
US7115587B2 (en) 2006-10-03
HRP20050149A2 (en) 2005-10-31
CY1110331T1 (el) 2015-01-14
MXPA05001865A (es) 2005-06-03
EP1542668B1 (en) 2009-04-15
EP1542668A2 (en) 2005-06-22
JP4729306B2 (ja) 2011-07-20
UA79984C2 (en) 2007-08-10
NO333458B1 (no) 2013-06-10
PL374798A1 (en) 2005-10-31
AU2003269965A1 (en) 2004-03-11
PT1542668E (pt) 2009-06-09
DE60327225D1 (de) 2009-05-28
GEP20063996B (en) 2006-12-11
WO2004017897A2 (en) 2004-03-04
NO20050661L (no) 2005-03-16
US20090186903A1 (en) 2009-07-23
ATE428423T1 (de) 2009-05-15
AR040887A1 (es) 2005-04-20
HRP20050149B1 (hr) 2014-09-12

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