PE20011322A1 - Suspensiones acuosas estabilizadas para uso parenteral - Google Patents

Suspensiones acuosas estabilizadas para uso parenteral

Info

Publication number
PE20011322A1
PE20011322A1 PE2001000431A PE2001000431A PE20011322A1 PE 20011322 A1 PE20011322 A1 PE 20011322A1 PE 2001000431 A PE2001000431 A PE 2001000431A PE 2001000431 A PE2001000431 A PE 2001000431A PE 20011322 A1 PE20011322 A1 PE 20011322A1
Authority
PE
Peru
Prior art keywords
aqueous suspensions
parenteral use
suspensions stabilized
stabilized
medroxy
Prior art date
Application number
PE2001000431A
Other languages
English (en)
Inventor
Alessandro Martini
Giuseppe Colombo
Lloyd E Fox
Original Assignee
Pharmacia & Upjohn Spa
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa, Upjohn Co filed Critical Pharmacia & Upjohn Spa
Publication of PE20011322A1 publication Critical patent/PE20011322A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens

Abstract

SE REFIERE A UNA FORMULACION EN SUSPENSION ACUOSA PARENTERAL QUE TIENE UN pH SUSTANCIALMENTE ESTABILIZADO DE 3 A 8 Y COMPRENDE a)UN COMPUESTO BIOLOGICAMENTE ACTIVO COMO EXEMESTANO, MEDROXI-PROGESTERONA-ACETATO, ESTRADIOL-CIPIONATO; b)DE 0,005%P/V O P/P Y 5%P/V O P/P DE L-METIONINA EN UNA CONCENTRACION EFECTIVA COMO PARA PRODUCIR UN EFECTO SUPER ADITIVO DE CONTROL DEL pH; c)UNA CONCENTRACION INFERIOR A 0,4% P/V O P/P DE UN BUFFER COMO SAL DEL ACIDO FOSFORICO
PE2001000431A 2000-05-15 2001-05-14 Suspensiones acuosas estabilizadas para uso parenteral PE20011322A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/571,395 US6495534B2 (en) 2000-05-15 2000-05-15 Stabilized aqueous suspensions for parenteral use

Publications (1)

Publication Number Publication Date
PE20011322A1 true PE20011322A1 (es) 2002-01-10

Family

ID=24283530

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001000431A PE20011322A1 (es) 2000-05-15 2001-05-14 Suspensiones acuosas estabilizadas para uso parenteral

Country Status (30)

Country Link
US (3) US6495534B2 (es)
EP (1) EP1282402B1 (es)
JP (1) JP4205341B2 (es)
KR (1) KR100828957B1 (es)
CN (1) CN100473376C (es)
AR (3) AR029924A1 (es)
AT (1) ATE313316T1 (es)
AU (2) AU6737101A (es)
BR (1) BR0110841A (es)
CA (1) CA2409059C (es)
CZ (1) CZ303872B6 (es)
DE (1) DE60116084T2 (es)
DK (1) DK1282402T3 (es)
EA (1) EA007682B1 (es)
EE (1) EE05376B1 (es)
ES (1) ES2254443T3 (es)
HK (1) HK1054194B (es)
HU (1) HU229800B1 (es)
IL (2) IL152537A (es)
IN (1) IN224279B (es)
MX (1) MXPA02011195A (es)
NO (1) NO332215B1 (es)
NZ (1) NZ522324A (es)
PE (1) PE20011322A1 (es)
PL (1) PL203075B1 (es)
SI (1) SI1282402T1 (es)
SK (1) SK287641B6 (es)
TW (1) TWI256310B (es)
WO (1) WO2001087266A1 (es)
ZA (1) ZA200208738B (es)

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Also Published As

Publication number Publication date
EE200200631A (et) 2004-04-15
AR029924A1 (es) 2003-07-23
EP1282402A1 (en) 2003-02-12
HK1054194B (zh) 2010-02-12
CZ303872B6 (cs) 2013-06-05
US20030114430A1 (en) 2003-06-19
CN1429101A (zh) 2003-07-09
HUP0302021A3 (en) 2011-03-28
SK15982002A3 (sk) 2003-05-02
IL152537A (en) 2007-06-17
HK1054194A1 (en) 2003-11-21
NO20025431D0 (no) 2002-11-13
NO332215B1 (no) 2012-07-30
ES2254443T3 (es) 2006-06-16
AR111695A2 (es) 2019-08-07
JP2003533467A (ja) 2003-11-11
NZ522324A (en) 2005-02-25
EA200201208A1 (ru) 2003-04-24
IL152537A0 (en) 2003-05-29
EA007682B1 (ru) 2006-12-29
DK1282402T3 (da) 2006-05-08
SI1282402T1 (sl) 2006-04-30
US20020115645A1 (en) 2002-08-22
EP1282402B1 (en) 2005-12-21
WO2001087266A1 (en) 2001-11-22
DE60116084T2 (de) 2006-08-17
CA2409059C (en) 2006-04-18
MXPA02011195A (es) 2003-03-10
AR098830A2 (es) 2016-06-15
AU6737101A (en) 2001-11-26
EE05376B1 (et) 2011-02-15
PL203075B1 (pl) 2009-08-31
IL165888A0 (en) 2006-01-15
PL365793A1 (en) 2005-01-10
BR0110841A (pt) 2003-03-11
NO20025431L (no) 2003-01-13
HUP0302021A2 (hu) 2003-09-29
US6495534B2 (en) 2002-12-17
SK287641B6 (sk) 2011-05-06
KR100828957B1 (ko) 2008-05-13
JP4205341B2 (ja) 2009-01-07
CN100473376C (zh) 2009-04-01
AU2001267371B2 (en) 2006-01-05
HU229800B1 (en) 2014-07-28
ATE313316T1 (de) 2006-01-15
TWI256310B (en) 2006-06-11
IN224279B (es) 2005-02-25
ZA200208738B (en) 2003-10-29
KR20030020280A (ko) 2003-03-08
CZ20023750A3 (cs) 2003-03-12
DE60116084D1 (de) 2006-01-26
CA2409059A1 (en) 2001-11-22
US20030130245A1 (en) 2003-07-10

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