PE20011033A1 - Compuestos esteroides con un anillo ciclopropano con actividad androgenica - Google Patents

Compuestos esteroides con un anillo ciclopropano con actividad androgenica

Info

Publication number
PE20011033A1
PE20011033A1 PE2000001285A PE0012852000A PE20011033A1 PE 20011033 A1 PE20011033 A1 PE 20011033A1 PE 2000001285 A PE2000001285 A PE 2000001285A PE 0012852000 A PE0012852000 A PE 0012852000A PE 20011033 A1 PE20011033 A1 PE 20011033A1
Authority
PE
Peru
Prior art keywords
alkyl
androgenic activity
steroid compounds
compounds
acyl
Prior art date
Application number
PE2000001285A
Other languages
English (en)
Spanish (es)
Inventor
Roberta Buma Bursi
Jaap Van Der Louw
Dirk Leysen
Gooijer Marcel Evert De
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of PE20011033A1 publication Critical patent/PE20011033A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PE2000001285A 1999-12-02 2000-12-01 Compuestos esteroides con un anillo ciclopropano con actividad androgenica PE20011033A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99204080 1999-12-02

Publications (1)

Publication Number Publication Date
PE20011033A1 true PE20011033A1 (es) 2001-10-11

Family

ID=8240955

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2000001285A PE20011033A1 (es) 1999-12-02 2000-12-01 Compuestos esteroides con un anillo ciclopropano con actividad androgenica

Country Status (27)

Country Link
US (1) US6706700B2 (cg-RX-API-DMAC10.html)
EP (1) EP1237904B1 (cg-RX-API-DMAC10.html)
JP (1) JP2003515543A (cg-RX-API-DMAC10.html)
CN (1) CN1166680C (cg-RX-API-DMAC10.html)
AR (1) AR026655A1 (cg-RX-API-DMAC10.html)
AT (1) ATE317396T1 (cg-RX-API-DMAC10.html)
AU (1) AU778017B2 (cg-RX-API-DMAC10.html)
CA (1) CA2390226A1 (cg-RX-API-DMAC10.html)
CO (1) CO5251441A1 (cg-RX-API-DMAC10.html)
CY (1) CY1106086T1 (cg-RX-API-DMAC10.html)
CZ (1) CZ301376B6 (cg-RX-API-DMAC10.html)
DE (1) DE60025958T2 (cg-RX-API-DMAC10.html)
DK (1) DK1237904T3 (cg-RX-API-DMAC10.html)
ES (1) ES2258037T3 (cg-RX-API-DMAC10.html)
HK (1) HK1047596B (cg-RX-API-DMAC10.html)
HU (1) HUP0203611A3 (cg-RX-API-DMAC10.html)
IL (1) IL149424A (cg-RX-API-DMAC10.html)
MX (1) MXPA02004939A (cg-RX-API-DMAC10.html)
NO (1) NO322422B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ518753A (cg-RX-API-DMAC10.html)
PE (1) PE20011033A1 (cg-RX-API-DMAC10.html)
PL (1) PL202999B1 (cg-RX-API-DMAC10.html)
RU (1) RU2242479C2 (cg-RX-API-DMAC10.html)
SK (1) SK287095B6 (cg-RX-API-DMAC10.html)
TW (1) TWI275593B (cg-RX-API-DMAC10.html)
WO (1) WO2001040255A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200203536B (cg-RX-API-DMAC10.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2204613T3 (es) * 1999-04-06 2004-05-01 Akzo Nobel N.V. Androgenos 7-alfa alquilo oralmente activos.
EP1470151B1 (en) * 2002-01-21 2009-12-30 N.V. Organon Process for the preparation of 7-alpha-methylsteroids
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
AU2012320423C1 (en) * 2011-10-07 2018-01-25 Estetra Srl Process for the production of estetrol
CU24523B1 (es) 2015-06-18 2021-06-08 Estetra Sprl Unidad de dosificación orodispersable que contiene un componente estetrol
EP3701944B1 (en) 2015-06-18 2021-12-08 Estetra SRL Orodispersible dosage unit containing an estetrol component
LT3310345T (lt) 2015-06-18 2021-06-25 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
MA44206B1 (fr) 2015-06-18 2021-04-30 Estetra Sprl Comprimé orodispersible comprenant estetrol
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
EP3781171B1 (en) 2018-04-19 2022-02-09 Estetra SRL Compounds and their uses for alleviating menopause-associated symptoms
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
CN111621141B (zh) * 2020-06-12 2022-04-08 广西大学 一种缓释型二氧化氯-水性聚氨酯抗菌膜及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3086027A (en) * 1960-01-22 1963-04-16 Lilly Co Eli 19-nor-4, 9(10)-steroids and process
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE19537626A1 (de) 1995-10-10 1997-04-17 Jenapharm Gmbh Steroide mit einer 14, 15-Methylengruppe
DE19827522A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh 14,15-Cyclopropanosteroide der 19-Nor-Androstanreihe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
ATE228143T1 (de) 1999-03-08 2002-12-15 Akzo Nobel Nv 14.beta.,17-alpha-hydroxymethylandrostan derivate als androgene

Also Published As

Publication number Publication date
NO20022564D0 (no) 2002-05-30
NO322422B1 (no) 2006-10-02
IL149424A (en) 2007-05-15
ZA200203536B (en) 2003-08-04
CN1402735A (zh) 2003-03-12
US6706700B2 (en) 2004-03-16
PL355689A1 (en) 2004-05-17
CZ20021894A3 (cs) 2002-08-14
AR026655A1 (es) 2003-02-19
CA2390226A1 (en) 2001-06-07
DE60025958D1 (de) 2006-04-20
HK1047596B (en) 2006-04-21
AU2838301A (en) 2001-06-12
CZ301376B6 (cs) 2010-02-03
PL202999B1 (pl) 2009-08-31
SK287095B6 (sk) 2009-12-07
NZ518753A (en) 2004-05-28
HK1047596A1 (en) 2003-02-28
SK7582002A3 (en) 2002-09-10
DE60025958T2 (de) 2006-07-27
RU2242479C2 (ru) 2004-12-20
HUP0203611A2 (hu) 2003-03-28
US20030100543A1 (en) 2003-05-29
WO2001040255A2 (en) 2001-06-07
WO2001040255A3 (en) 2001-11-15
JP2003515543A (ja) 2003-05-07
NO20022564L (no) 2002-05-30
MXPA02004939A (es) 2003-05-23
ATE317396T1 (de) 2006-02-15
CY1106086T1 (el) 2011-06-08
CN1166680C (zh) 2004-09-15
EP1237904B1 (en) 2006-02-08
DK1237904T3 (da) 2006-06-06
CO5251441A1 (es) 2003-02-28
HUP0203611A3 (en) 2004-07-28
TWI275593B (en) 2007-03-11
AU778017B2 (en) 2004-11-11
ES2258037T3 (es) 2006-08-16
IL149424A0 (en) 2002-11-10
EP1237904A2 (en) 2002-09-11

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Legal Events

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FD Application declared void or lapsed