PE20010151A1 - Nuevas formas cristalinas de un antibiotico macrolido - Google Patents
Nuevas formas cristalinas de un antibiotico macrolidoInfo
- Publication number
- PE20010151A1 PE20010151A1 PE2000000459A PE0004592000A PE20010151A1 PE 20010151 A1 PE20010151 A1 PE 20010151A1 PE 2000000459 A PE2000000459 A PE 2000000459A PE 0004592000 A PE0004592000 A PE 0004592000A PE 20010151 A1 PE20010151 A1 PE 20010151A1
- Authority
- PE
- Peru
- Prior art keywords
- compound
- crystalline forms
- new crystalline
- macrolide antibiotic
- refers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
SE REFIERE A UNA FORMA CRISTALINA DE UN MACROLIDO DE FORMULA I, SE PRESENTA EN FORMA ANHIDRA, MONOHIDRATO O SESQUAHIDRATO; SE CARACTERIZA POR SU PATRON DE DIFRACCION DE RAYOS X; ESPECTRO DE CALORIMETRIA DE BARRIDO DIFERENCIAL; POR NO SER HIGROSCOPICA DURANTE 72 HORAS A 7 DIAS, CUANDO SE ALMACENA A UNA HUMEDAD RELATIVA DE 87% Y 25%. TAMBIEN SE REFIERE A UN METODO PARA LA PREPARACION QUE COMPRENDE DISOLVER EL COMPUESTO I EN UN DISOLVENTE SELECCIONADO DE ANHIDRO, NO ACUOSO, O ACETATO DE ETILO; ENFRIAR LA SOLUCION HASTA UNA TEMPERATURA A LA CUAL NO ES SOLUBLE EL COMPUESTO I EN LA SOLUCION. EL COMPUESTO I PUEDE SER UTIL PARA EL TRATAMIENTO DE UNA INFECCION BACTERIANA O PROTOZOARIA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13464499P | 1999-05-18 | 1999-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20010151A1 true PE20010151A1 (es) | 2001-02-08 |
Family
ID=22464300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000000459A PE20010151A1 (es) | 1999-05-18 | 2000-05-16 | Nuevas formas cristalinas de un antibiotico macrolido |
Country Status (43)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6465437B1 (en) * | 1999-06-30 | 2002-10-15 | Pfizer Inc. | Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition |
| EP1250343B1 (en) * | 2000-01-27 | 2003-06-25 | Pfizer Products Inc. | Azalide antibiotic compositions |
| MXPA03009786A (es) * | 2001-04-27 | 2004-01-29 | Pfizer Prod Inc | Procedimiento para preparar derivados de 9-desoxo-9a-aza-9a-homoeritromicina a 4"-sustituidos. |
| EP1435359A1 (en) * | 2002-12-31 | 2004-07-07 | Alembic Limited | A process for the purification of roxithromycin |
| US7384921B2 (en) * | 2004-02-20 | 2008-06-10 | Enanta Pharmaceuticals, Inc. | Polymorphic forms of 6-11 bicyclic ketolide derivatives |
| AR075340A1 (es) * | 2009-01-30 | 2011-03-23 | Glaxosmithkline Zagreb | 3'-n-desmetil-4''-o-(2-dietilaminoetanoil)-6-o-metil-9a-aza-9a-homoeritromicina a,formas cristalinas 1, 2 y 3, proceso para su preparacion, composicion farmaceutica que lo comprende y su uso para la preparacion de un medicamento util para el tratamiento de enfermedades inflamatorias |
| EP2402355A1 (en) * | 2010-07-01 | 2012-01-04 | Novartis AG | Crystalline anhydrous forms II and III of Tulathromycin |
| WO2013013834A1 (en) | 2011-07-27 | 2013-01-31 | Farma Grs, D.O.O. | New crystalline forms of tulathromycin |
| CN106008622A (zh) * | 2016-08-02 | 2016-10-12 | 海门慧聚药业有限公司 | 泰拉霉素新晶型及其制备 |
| CN109942652B (zh) * | 2017-12-21 | 2022-04-26 | 洛阳惠中兽药有限公司 | 一种莱柯霉素晶型ⅰ及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2066324C1 (ru) * | 1987-07-09 | 1996-09-10 | Пфайзер Инк. | Кристаллический дигидрат азитромицина и способ его получения |
| US5441939A (en) * | 1994-03-04 | 1995-08-15 | Pfizer Inc. | 3"-desmethoxy derivatives of erythromycin and azithromycin |
| US5844105A (en) * | 1996-07-29 | 1998-12-01 | Abbott Laboratories | Preparation of crystal form II of clarithromycin |
| HN1998000086A (es) * | 1997-06-11 | 1999-03-08 | Pfizer Prod Inc | Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos. |
-
2000
- 2000-04-14 CN CNB008077029A patent/CN1203084C/zh not_active Expired - Fee Related
- 2000-04-14 DK DK00914336T patent/DK1189912T3/da active
- 2000-04-14 AP APAP/P/2001/002325A patent/AP2001002325A0/en unknown
- 2000-04-14 CA CA002372206A patent/CA2372206C/en not_active Expired - Lifetime
- 2000-04-14 AU AU35729/00A patent/AU772283B2/en not_active Ceased
- 2000-04-14 YU YU76601A patent/YU76601A/sh unknown
- 2000-04-14 AT AT00914336T patent/ATE392427T1/de not_active IP Right Cessation
- 2000-04-14 NZ NZ514765A patent/NZ514765A/en unknown
- 2000-04-14 PT PT00914336T patent/PT1189912E/pt unknown
- 2000-04-14 EA EA200100984A patent/EA003417B1/ru not_active IP Right Cessation
- 2000-04-14 KR KR10-2001-7014687A patent/KR100474229B1/ko not_active IP Right Cessation
- 2000-04-14 PL PL00353316A patent/PL353316A1/xx unknown
- 2000-04-14 DE DE60038610T patent/DE60038610T2/de not_active Expired - Lifetime
- 2000-04-14 OA OA1200100283A patent/OA11876A/en unknown
- 2000-04-14 HU HU0201341A patent/HUP0201341A3/hu unknown
- 2000-04-14 WO PCT/IB2000/000463 patent/WO2000069874A1/en active IP Right Grant
- 2000-04-14 BR BR0011300-0A patent/BR0011300A/pt not_active Application Discontinuation
- 2000-04-14 JP JP2000618290A patent/JP3897983B2/ja not_active Expired - Fee Related
- 2000-04-14 ES ES00914336T patent/ES2302689T3/es not_active Expired - Lifetime
- 2000-04-14 UA UA2001117852A patent/UA67842C2/uk unknown
- 2000-04-14 IL IL14594600A patent/IL145946A0/xx active IP Right Grant
- 2000-04-14 SK SK1647-2001A patent/SK16472001A3/sk unknown
- 2000-04-14 EP EP00914336A patent/EP1189912B1/en not_active Expired - Lifetime
- 2000-04-14 CZ CZ20014120A patent/CZ20014120A3/cs unknown
- 2000-04-14 MX MXPA01011914A patent/MXPA01011914A/es active IP Right Grant
- 2000-04-25 HN HN2000000056A patent/HN2000000056A/es unknown
- 2000-05-02 US US09/563,792 patent/US6583274B1/en not_active Expired - Lifetime
- 2000-05-05 PA PA20008495001A patent/PA8495001A1/es unknown
- 2000-05-12 TW TW089109175A patent/TWI225066B/zh not_active IP Right Cessation
- 2000-05-15 MY MYPI20002125A patent/MY133397A/en unknown
- 2000-05-15 UY UY26144A patent/UY26144A1/es not_active Application Discontinuation
- 2000-05-16 AR ARP000102353A patent/AR020030A1/es not_active Application Discontinuation
- 2000-05-16 PE PE2000000459A patent/PE20010151A1/es not_active Application Discontinuation
- 2000-05-17 MA MA25979A patent/MA26735A1/fr unknown
- 2000-05-17 GT GT200000072A patent/GT200000072A/es unknown
- 2000-05-17 DZ DZ000086A patent/DZ3043A1/xx active
- 2000-05-17 TN TNTNSN00103A patent/TNSN00103A1/fr unknown
-
2001
- 2001-10-15 IL IL145946A patent/IL145946A/en unknown
- 2001-10-26 IS IS6127A patent/IS6127A/is unknown
- 2001-11-15 ZA ZA200109420A patent/ZA200109420B/xx unknown
- 2001-11-16 HR HR20010849A patent/HRP20010849A2/hr not_active Application Discontinuation
- 2001-11-16 NO NO20015598A patent/NO320195B1/no unknown
- 2001-11-26 BG BG106150A patent/BG106150A/bg unknown
-
2002
- 2002-09-26 HK HK02107017.2A patent/HK1045521B/zh not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |