JPS54125672A - Pseudomonic acid amide derivative, or its salt, and their preparation - Google Patents

Pseudomonic acid amide derivative, or its salt, and their preparation

Info

Publication number
JPS54125672A
JPS54125672A JP3376278A JP3376278A JPS54125672A JP S54125672 A JPS54125672 A JP S54125672A JP 3376278 A JP3376278 A JP 3376278A JP 3376278 A JP3376278 A JP 3376278A JP S54125672 A JPS54125672 A JP S54125672A
Authority
JP
Japan
Prior art keywords
salt
acid amide
alkyl
aryl
pseudomonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3376278A
Other languages
Japanese (ja)
Other versions
JPS6157313B2 (en
Inventor
Tomohiko Munakata
Takanori Oe
Mineo Tsuruta
Katsuyoshi Iimori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP3376278A priority Critical patent/JPS54125672A/en
Publication of JPS54125672A publication Critical patent/JPS54125672A/en
Publication of JPS6157313B2 publication Critical patent/JPS6157313B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NEW MATERIAL:A pseudomonic acid amide derivative or its salt of formula I (R<1>,<2> are alkyl, substituted alkyl, alkenyl, alkynyl, aryl, substituted aryl, etc.; or one of the R<1> and R<2> is H and the other is alkyl, substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, etc.). EXAMPLE:N-Hydroxy-N-methylpseudomonic acid amide. USE:Remedy for the infectious diseases of man and animal by bacteria. Strong antibacterial activity to Gram-positive bacteria such as Staphylococcus aureus, Streptococcus biogenes, etc., and effective to the penicillin-resistant or macrolide-resistant variant thereof. Long acting effectiveness. For oral or parenteral administration. PROCESS:The compound I is prepared by reacting the compound II with pseudomonic acid, its salt, or its reactive derivative in an inert solvent at -50 deg.C - room temp.
JP3376278A 1978-03-23 1978-03-23 Pseudomonic acid amide derivative, or its salt, and their preparation Granted JPS54125672A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3376278A JPS54125672A (en) 1978-03-23 1978-03-23 Pseudomonic acid amide derivative, or its salt, and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3376278A JPS54125672A (en) 1978-03-23 1978-03-23 Pseudomonic acid amide derivative, or its salt, and their preparation

Publications (2)

Publication Number Publication Date
JPS54125672A true JPS54125672A (en) 1979-09-29
JPS6157313B2 JPS6157313B2 (en) 1986-12-06

Family

ID=12395433

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3376278A Granted JPS54125672A (en) 1978-03-23 1978-03-23 Pseudomonic acid amide derivative, or its salt, and their preparation

Country Status (1)

Country Link
JP (1) JPS54125672A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292892A (en) * 1991-05-07 1994-03-08 Sankyo Company, Limited Anti-bacterial compound and pharmaceutical compositions thereof
US5380723A (en) * 1991-10-07 1995-01-10 Nisshin Flour Milling Co., Ltd. Indole derivatives
US5399711A (en) * 1992-09-18 1995-03-21 Sankyo Company, Limited Thiomarinol compounds

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292892A (en) * 1991-05-07 1994-03-08 Sankyo Company, Limited Anti-bacterial compound and pharmaceutical compositions thereof
US5405762A (en) * 1991-05-07 1995-04-11 Sankyo Company, Limited Culture of alteromonas and process of using the same to produce an antibacterial compound
US5380723A (en) * 1991-10-07 1995-01-10 Nisshin Flour Milling Co., Ltd. Indole derivatives
US5399711A (en) * 1992-09-18 1995-03-21 Sankyo Company, Limited Thiomarinol compounds

Also Published As

Publication number Publication date
JPS6157313B2 (en) 1986-12-06

Similar Documents

Publication Publication Date Title
JPS5649382A (en) 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
ES455089A1 (en) Oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid processes for preparing them and pharmaceutical compositions incorporating them
ES8606262A1 (en) Pleuromutilin derivatives, process for their preparation and their use.
JPS5492951A (en) Novel aminoglycoside derivative
KR840004118A (en) Method for preparing cephalosporin derivative
ES8202022A1 (en) 1*88naphthylidine derivative and its salt
JPS54125672A (en) Pseudomonic acid amide derivative, or its salt, and their preparation
ES431497A1 (en) S-triazolo(1,5-a)pyridine derivative
JPS54103871A (en) Pseudomonic acid derivative and its preparation
NO147840C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF POLYEN MACROLID ANTIBIOTICA DERIVATIVES
JPS554337A (en) Cephalosporin analogs
JPS56103185A (en) Malonamidoxa-dethia-cephem compound
NO171502C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE THIADIAZOLYLACETAMIDE CEFEM DERIVATIVES
JPS5655388A (en) Benzo ij quinolidine-2-carboxylic acid derivative, and its preparation
IE36346B1 (en) Antibacterial agents and a process for the preparation thereof
US4121041A (en) 7-(Amidinothio)acetamido-7-methoxy cephalosporins
JPS5540656A (en) Substituted quinoline-carboxylic acid derivative
JPS54103872A (en) Antibiotic pseudomonic acid derivative and its preparation
JPS54106474A (en) Pseudomonic acid derivative and its preparation
AT314086B (en) Process for the preparation of new cephalosporin compounds
IE40057B1 (en) 4-oxo-1-pyridinyl penicillin and cephalosporin derivatives
IE39830B1 (en) 7-(substituted 1-cyclohexenyl and 1,4 cyclohexadienyl-acetamido)-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids
JPS55115898A (en) 3&#34;,4&#34;-diacyltylosin derivative
JPS646242A (en) Tertiary amine derivative, production thereof and fungicide for agriculture and garden
ES8407057A1 (en) Cephalosporin antibiotics.