JPS54103872A - Antibiotic pseudomonic acid derivative and its preparation - Google Patents

Antibiotic pseudomonic acid derivative and its preparation

Info

Publication number
JPS54103872A
JPS54103872A JP1109478A JP1109478A JPS54103872A JP S54103872 A JPS54103872 A JP S54103872A JP 1109478 A JP1109478 A JP 1109478A JP 1109478 A JP1109478 A JP 1109478A JP S54103872 A JPS54103872 A JP S54103872A
Authority
JP
Japan
Prior art keywords
formula
compound
pseudomonic acid
acid derivative
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1109478A
Other languages
Japanese (ja)
Inventor
Tomohiko Munakata
Michiharu Nobutoki
Hisashi Kono
Katsuyoshi Iimori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP1109478A priority Critical patent/JPS54103872A/en
Publication of JPS54103872A publication Critical patent/JPS54103872A/en
Pending legal-status Critical Current

Links

Landscapes

  • Pyrane Compounds (AREA)

Abstract

NEW MATERIAL:An antibiotic pseudomonic acid derivative of formula I.
USE: Remedies for infectious diseases of men and animals by bacteria, having powerful antibacterial activity against Gram-positive bacteria, e.g. Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus pneumonia, penicillin- or macrolide- resistant bacteria for a long duration. Useful as an intermediate for synthesis of other antibiotics.
PROCESS: An antibiotic pseudomonic acid of formula II is changed into the corresponding halohydrin compound by the well-known method, and reduced with a suitable reducing agent, e.g. zinc dust or phosphine to give the compound of formula I. The halohydrin compound is obtained by dissolving a compound of formula II in an organic solvent containing lithium bromide, and by adding hydrobromic acid to the solution.
COPYRIGHT: (C)1979,JPO&Japio
JP1109478A 1978-02-02 1978-02-02 Antibiotic pseudomonic acid derivative and its preparation Pending JPS54103872A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1109478A JPS54103872A (en) 1978-02-02 1978-02-02 Antibiotic pseudomonic acid derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1109478A JPS54103872A (en) 1978-02-02 1978-02-02 Antibiotic pseudomonic acid derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS54103872A true JPS54103872A (en) 1979-08-15

Family

ID=11768399

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1109478A Pending JPS54103872A (en) 1978-02-02 1978-02-02 Antibiotic pseudomonic acid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS54103872A (en)

Similar Documents

Publication Publication Date Title
JPS54103872A (en) Antibiotic pseudomonic acid derivative and its preparation
JPS54103871A (en) Pseudomonic acid derivative and its preparation
JPS5746988A (en) Novel penicillin derivative and its preparation
JPS5732290A (en) Novel penicillin derivative and its preparation
JPS575000A (en) Tylosin derivative
JPS54125672A (en) Pseudomonic acid amide derivative, or its salt, and their preparation
JPS5490179A (en) Antibiotic pseudomonic acid derivative and its preparation
JPS56122397A (en) Marcolides
JPS54144392A (en) Cephalosporin derivative
IE40057B1 (en) 4-oxo-1-pyridinyl penicillin and cephalosporin derivatives
JPS54125673A (en) Pseudomonic acid neopentyl ester
JPS5655388A (en) Benzo ij quinolidine-2-carboxylic acid derivative, and its preparation
JPS5540656A (en) Substituted quinoline-carboxylic acid derivative
JPS55164691A (en) Novel 7-methoxycephalosporanic acid derivative, its optically active substance, its salt, and its preparation
JPS54117478A (en) New antibiotics fortimicin kg1, kg2, and kg3, and their preparation
JPS5555198A (en) Novel antibiotic substance
JPS51133486A (en) Process for preparing an antibacterial substance by a microorganism wh ich belongs to gnomonia
JPS54106474A (en) Pseudomonic acid derivative and its preparation
JPS55115898A (en) 3",4"-diacyltylosin derivative
JPS5579394A (en) Novel 7-methoxycephalosporin derivative
JPS5466679A (en) Novel antibiotic substance fortimicin kf and fortimicin kg, and their preparation
JPS5473788A (en) Antibiotic n-desacetyl ps-5
JPS54135771A (en) Novel antibiotic substance 4a-epinanaomycin b and its preparation
GB1074235A (en) Antibiotics r-451b(x)and r-451d(x)and processes for their manufacture
JPS5718694A (en) 9-dihydromycinamicin