JPS54103871A - Pseudomonic acid derivative and its preparation - Google Patents

Pseudomonic acid derivative and its preparation

Info

Publication number
JPS54103871A
JPS54103871A JP864878A JP864878A JPS54103871A JP S54103871 A JPS54103871 A JP S54103871A JP 864878 A JP864878 A JP 864878A JP 864878 A JP864878 A JP 864878A JP S54103871 A JPS54103871 A JP S54103871A
Authority
JP
Japan
Prior art keywords
pseudomonic acid
formula
salt
bacteria
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP864878A
Other languages
Japanese (ja)
Other versions
JPS6157312B2 (en
Inventor
Tomohiko Munakata
Takanori Oe
Minoru Moriwaki
Katsuyoshi Iimori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP864878A priority Critical patent/JPS54103871A/en
Publication of JPS54103871A publication Critical patent/JPS54103871A/en
Publication of JPS6157312B2 publication Critical patent/JPS6157312B2/ja
Granted legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A pseudomonic acid derivative of formula I: (R is H, 1-6C alkyl, or aryl group; X is O or S). EXAMPLE:1-Pseudomonic acid 4-phenyl-thiosemicarbazide. USE:Remedies for infectious diseases of men and animals by bacteria, having powerful antibacterial ability against Gram-positive bacteria, such as Staphylococcus aureus, Streptococcus pyogenes or Streptococcus pneumoniae, effective against penicillin- or macrolide-resistant bacteria. PROCESS:An inorganic salt (sodium salt) or organic salt (triethylamine salt) of pseudomonic acid is reacted with a monoalkyl carbonate, e.g. ethyl carbonate, or an organic halide, e.g. isovaleryl chloride, to form a mixed acid anhydride, which is reacted with a compound of formula II to give the compound of formula I.
JP864878A 1978-01-28 1978-01-28 Pseudomonic acid derivative and its preparation Granted JPS54103871A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP864878A JPS54103871A (en) 1978-01-28 1978-01-28 Pseudomonic acid derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP864878A JPS54103871A (en) 1978-01-28 1978-01-28 Pseudomonic acid derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS54103871A true JPS54103871A (en) 1979-08-15
JPS6157312B2 JPS6157312B2 (en) 1986-12-06

Family

ID=11698754

Family Applications (1)

Application Number Title Priority Date Filing Date
JP864878A Granted JPS54103871A (en) 1978-01-28 1978-01-28 Pseudomonic acid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS54103871A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292892A (en) * 1991-05-07 1994-03-08 Sankyo Company, Limited Anti-bacterial compound and pharmaceutical compositions thereof
US5380723A (en) * 1991-10-07 1995-01-10 Nisshin Flour Milling Co., Ltd. Indole derivatives
US5399711A (en) * 1992-09-18 1995-03-21 Sankyo Company, Limited Thiomarinol compounds

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61236028A (en) * 1985-04-10 1986-10-21 Csk Corp Optical recording medium
JPS61236029A (en) * 1985-04-10 1986-10-21 Csk Corp Optical recording medium
JPH0250282A (en) * 1988-08-12 1990-02-20 Casio Comput Co Ltd Data reading device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292892A (en) * 1991-05-07 1994-03-08 Sankyo Company, Limited Anti-bacterial compound and pharmaceutical compositions thereof
US5405762A (en) * 1991-05-07 1995-04-11 Sankyo Company, Limited Culture of alteromonas and process of using the same to produce an antibacterial compound
US5380723A (en) * 1991-10-07 1995-01-10 Nisshin Flour Milling Co., Ltd. Indole derivatives
US5399711A (en) * 1992-09-18 1995-03-21 Sankyo Company, Limited Thiomarinol compounds

Also Published As

Publication number Publication date
JPS6157312B2 (en) 1986-12-06

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