ES8202022A1 - 1*88naphthylidine derivative and its salt - Google Patents
1*88naphthylidine derivative and its saltInfo
- Publication number
- ES8202022A1 ES8202022A1 ES491221A ES491221A ES8202022A1 ES 8202022 A1 ES8202022 A1 ES 8202022A1 ES 491221 A ES491221 A ES 491221A ES 491221 A ES491221 A ES 491221A ES 8202022 A1 ES8202022 A1 ES 8202022A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- naphthylidine
- lower alkyl
- salt
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
Abstract
NEW MATERIAL:A 1,8-naphthylidine derivative of formula I (X is halogen R is amino R1 is lower alkyl, lower alkenyl, lower alkynyl R2 is H, lower alkyl), and its salt. EXAMPLE:6 -Chloro-1-ethyl-1, 4-dihydro-4-oxo-7-pyrrolidino-1, 8-naphthylidine-3- carboxylic acid. USE:Antibacterial agent especially effective to gram negative bacteria including Pseudomonas aeruginosa. Medicine, animal drug, fish drug, food preservative, intermediate of various compounds, etc. PROCESS:The title compound I is prepared, e.g. by reacting a compound II (Y is a functional group which can be replaced with amine group) with an amine R-H in an inert solvent such as ethanol, etc., at 20-180 deg.C, pref. 50-150 deg.C, for 20-60 minutes. The compound II is also novel.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10423578A JPS5531042A (en) | 1978-08-25 | 1978-08-25 | 1,8-naphthylidine derivative and its salt |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8202022A1 true ES8202022A1 (en) | 1982-01-01 |
| ES491221A0 ES491221A0 (en) | 1982-01-01 |
Family
ID=14375290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491221A Granted ES491221A0 (en) | 1978-08-25 | 1980-05-02 | A PROCEDURE FOR PREPARING A 1,8-NAFTIRI- DINE COMPOUND |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5531042A (en) |
| ES (1) | ES491221A0 (en) |
| PL (1) | PL120155B1 (en) |
| SU (2) | SU1075976A3 (en) |
| ZA (1) | ZA794478B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5770889A (en) * | 1980-10-21 | 1982-05-01 | Dainippon Pharmaceut Co Ltd | 1-ethyl-1,8-naphthyridine derivative and salt thereof |
| JPS5772981A (en) * | 1980-10-22 | 1982-05-07 | Dainippon Pharmaceut Co Ltd | 1,8-naphthyridine derivative and its salt |
| JPS57106681A (en) * | 1980-12-24 | 1982-07-02 | Dainippon Pharmaceut Co Ltd | 1,8-naphthyridine derivative and its salt |
| US4382937A (en) * | 1981-02-27 | 1983-05-10 | Dainippon Pharmaceutical Co., Ltd. | Naphthyridine derivatives and their use as anti-bacterials |
| JPS57142983A (en) * | 1981-02-27 | 1982-09-03 | Dainippon Pharmaceut Co Ltd | 1-vinyl-1,8-naphthyridine derivative and its salt |
| JPS57146775A (en) * | 1981-03-06 | 1982-09-10 | Dainippon Pharmaceut Co Ltd | 1,8-naphthyridine derivative and its salt |
| JPS60112790A (en) * | 1983-11-21 | 1985-06-19 | Dainippon Pharmaceut Co Ltd | Pyridylnaphthyridine derivative |
| JPS60126284A (en) * | 1983-12-09 | 1985-07-05 | Dainippon Pharmaceut Co Ltd | Pyridonecarboxylic acid derivative and salt thereof |
| DE3508816A1 (en) * | 1985-01-10 | 1986-07-10 | Bayer Ag, 5090 Leverkusen | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTYRIDINE-3-CARBONIC ACIDS |
| EP0787720B1 (en) * | 1994-10-20 | 2003-07-16 | Wakunaga Seiyaku Kabushiki Kaisha | Pyridonecarboxylate derivative or salt thereof and antibacterial containing the same as active ingredient |
| WO1997040036A1 (en) | 1996-04-19 | 1997-10-30 | Wakunaga Pharmaceutical Co., Ltd. | Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing the same as the active ingredient |
| KR100768034B1 (en) | 1999-03-17 | 2007-10-17 | 다이이찌 세이야꾸 가부시기가이샤 | Pharmaceutical composition |
| WO2001017991A1 (en) | 1999-09-02 | 2001-03-15 | Wakunaga Pharmaceutical Co., Ltd. | Quinolinecarboxylic acid derivative or its salt |
-
1978
- 1978-08-25 JP JP10423578A patent/JPS5531042A/en active Granted
-
1979
- 1979-08-24 SU SU792804598A patent/SU1075976A3/en active
- 1979-08-24 PL PL22609579A patent/PL120155B1/en unknown
- 1979-08-24 ZA ZA00794478A patent/ZA794478B/en unknown
-
1980
- 1980-05-02 ES ES491221A patent/ES491221A0/en active Granted
- 1980-09-03 SU SU802976304A patent/SU1037841A3/en active
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5710109B2 (en) | 1982-02-24 |
| SU1037841A3 (en) | 1983-08-23 |
| JPS5531042A (en) | 1980-03-05 |
| SU1075976A3 (en) | 1984-02-23 |
| ZA794478B (en) | 1981-04-29 |
| PL120155B1 (en) | 1982-02-27 |
| ES491221A0 (en) | 1982-01-01 |
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