ZA200109420B - Novel crystalline forms of a macrolide antibiotic. - Google Patents

Novel crystalline forms of a macrolide antibiotic.

Info

Publication number
ZA200109420B
ZA200109420B ZA200109420A ZA200109420A ZA200109420B ZA 200109420 B ZA200109420 B ZA 200109420B ZA 200109420 A ZA200109420 A ZA 200109420A ZA 200109420 A ZA200109420 A ZA 200109420A ZA 200109420 B ZA200109420 B ZA 200109420B
Authority
ZA
South Africa
Prior art keywords
crystalline forms
novel crystalline
macrolide antibiotic
macrolide
antibiotic
Prior art date
Application number
ZA200109420A
Other languages
English (en)
Inventor
Robert John Rafka
Douglas John Meldrum Allen
Colman Brendan Ragan
Barry James Morton
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200109420B publication Critical patent/ZA200109420B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
ZA200109420A 1999-05-18 2001-11-15 Novel crystalline forms of a macrolide antibiotic. ZA200109420B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13464499P 1999-05-18 1999-05-18

Publications (1)

Publication Number Publication Date
ZA200109420B true ZA200109420B (en) 2002-11-15

Family

ID=22464300

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200109420A ZA200109420B (en) 1999-05-18 2001-11-15 Novel crystalline forms of a macrolide antibiotic.

Country Status (43)

Country Link
US (1) US6583274B1 (es)
EP (1) EP1189912B1 (es)
JP (1) JP3897983B2 (es)
KR (1) KR100474229B1 (es)
CN (1) CN1203084C (es)
AP (1) AP2001002325A0 (es)
AR (1) AR020030A1 (es)
AT (1) ATE392427T1 (es)
AU (1) AU772283B2 (es)
BG (1) BG106150A (es)
BR (1) BR0011300A (es)
CA (1) CA2372206C (es)
CZ (1) CZ20014120A3 (es)
DE (1) DE60038610T2 (es)
DK (1) DK1189912T3 (es)
DZ (1) DZ3043A1 (es)
EA (1) EA003417B1 (es)
ES (1) ES2302689T3 (es)
GT (1) GT200000072A (es)
HK (1) HK1045521B (es)
HN (1) HN2000000056A (es)
HR (1) HRP20010849A2 (es)
HU (1) HUP0201341A3 (es)
IL (2) IL145946A0 (es)
IS (1) IS6127A (es)
MA (1) MA26735A1 (es)
MX (1) MXPA01011914A (es)
MY (1) MY133397A (es)
NO (1) NO320195B1 (es)
NZ (1) NZ514765A (es)
OA (1) OA11876A (es)
PA (1) PA8495001A1 (es)
PE (1) PE20010151A1 (es)
PL (1) PL353316A1 (es)
PT (1) PT1189912E (es)
SK (1) SK16472001A3 (es)
TN (1) TNSN00103A1 (es)
TW (1) TWI225066B (es)
UA (1) UA67842C2 (es)
UY (1) UY26144A1 (es)
WO (1) WO2000069874A1 (es)
YU (1) YU76601A (es)
ZA (1) ZA200109420B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
DK1250343T3 (da) * 2000-01-27 2003-09-22 Pfizer Prod Inc Sammensætninger med et azalid antibiotikum
CA2445306C (en) * 2001-04-27 2008-02-12 Pfizer Products Inc. Process for preparing 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
AU2003271408B2 (en) * 2002-12-31 2008-07-17 Alembic Limited A process for the purification of roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
US8227428B2 (en) * 2009-01-30 2012-07-24 Glaxo Group Limited Anti-infammatory macrolide
EP2402355A1 (en) * 2010-07-01 2012-01-04 Novartis AG Crystalline anhydrous forms II and III of Tulathromycin
WO2013013834A1 (en) 2011-07-27 2013-01-31 Farma Grs, D.O.O. New crystalline forms of tulathromycin
CN106008622A (zh) * 2016-08-02 2016-10-12 海门慧聚药业有限公司 泰拉霉素新晶型及其制备
CN109942652B (zh) * 2017-12-21 2022-04-26 洛阳惠中兽药有限公司 一种莱柯霉素晶型ⅰ及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989000576A1 (en) * 1987-07-09 1989-01-26 Pfizer Inc. Azithromycin dihydrate
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5844105A (en) * 1996-07-29 1998-12-01 Abbott Laboratories Preparation of crystal form II of clarithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
HUP0201341A2 (en) 2002-08-28
HK1045521A1 (en) 2002-11-29
YU76601A (sh) 2004-09-03
DE60038610D1 (de) 2008-05-29
BG106150A (bg) 2002-05-31
TNSN00103A1 (fr) 2005-11-10
WO2000069874A1 (en) 2000-11-23
IL145946A0 (en) 2002-07-25
EP1189912A1 (en) 2002-03-27
PE20010151A1 (es) 2001-02-08
CA2372206A1 (en) 2000-11-23
CN1203084C (zh) 2005-05-25
JP2002544283A (ja) 2002-12-24
KR100474229B1 (ko) 2005-03-08
NO320195B1 (no) 2005-11-14
AU772283B2 (en) 2004-04-22
NZ514765A (en) 2004-05-28
MXPA01011914A (es) 2002-05-06
UY26144A1 (es) 2000-12-29
ATE392427T1 (de) 2008-05-15
CZ20014120A3 (cs) 2003-01-15
PT1189912E (pt) 2008-05-16
MY133397A (en) 2007-11-30
SK16472001A3 (sk) 2003-02-04
HN2000000056A (es) 2001-02-02
GT200000072A (es) 2001-11-08
EP1189912B1 (en) 2008-04-16
US6583274B1 (en) 2003-06-24
EA200100984A1 (ru) 2002-06-27
HUP0201341A3 (en) 2003-03-28
PL353316A1 (en) 2003-11-17
UA67842C2 (uk) 2004-07-15
EA003417B1 (ru) 2003-04-24
CA2372206C (en) 2006-01-10
AP2001002325A0 (en) 2001-12-31
KR20020007415A (ko) 2002-01-26
PA8495001A1 (es) 2002-02-21
CN1351607A (zh) 2002-05-29
DZ3043A1 (fr) 2004-03-27
OA11876A (en) 2006-03-27
IL145946A (en) 2007-06-17
MA26735A1 (fr) 2004-12-20
HK1045521B (zh) 2005-12-09
HRP20010849A2 (en) 2003-04-30
NO20015598D0 (no) 2001-11-16
AR020030A1 (es) 2002-03-27
ES2302689T3 (es) 2008-08-01
BR0011300A (pt) 2002-02-26
JP3897983B2 (ja) 2007-03-28
AU3572900A (en) 2000-12-05
IS6127A (is) 2001-10-26
DK1189912T3 (da) 2008-06-30
NO20015598L (no) 2002-01-08
DE60038610T2 (de) 2009-06-25
TWI225066B (en) 2004-12-11

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