DK1189912T3 - Nye krystallinske former af et makrolid antibiotikum - Google Patents

Nye krystallinske former af et makrolid antibiotikum

Info

Publication number
DK1189912T3
DK1189912T3 DK00914336T DK00914336T DK1189912T3 DK 1189912 T3 DK1189912 T3 DK 1189912T3 DK 00914336 T DK00914336 T DK 00914336T DK 00914336 T DK00914336 T DK 00914336T DK 1189912 T3 DK1189912 T3 DK 1189912T3
Authority
DK
Denmark
Prior art keywords
crystalline forms
new crystalline
macrolide antibiotic
macrolide
antibiotic
Prior art date
Application number
DK00914336T
Other languages
Danish (da)
English (en)
Inventor
Robert John Rafka
Douglas John Meldrum Allen
Colman Brendan Ragan
Barry James Morton
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK1189912T3 publication Critical patent/DK1189912T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK00914336T 1999-05-18 2000-04-14 Nye krystallinske former af et makrolid antibiotikum DK1189912T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13464499P 1999-05-18 1999-05-18
PCT/IB2000/000463 WO2000069874A1 (en) 1999-05-18 2000-04-14 Novel crystalline forms of a macrolide antibiotic

Publications (1)

Publication Number Publication Date
DK1189912T3 true DK1189912T3 (da) 2008-06-30

Family

ID=22464300

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00914336T DK1189912T3 (da) 1999-05-18 2000-04-14 Nye krystallinske former af et makrolid antibiotikum

Country Status (43)

Country Link
US (1) US6583274B1 (es)
EP (1) EP1189912B1 (es)
JP (1) JP3897983B2 (es)
KR (1) KR100474229B1 (es)
CN (1) CN1203084C (es)
AP (1) AP2001002325A0 (es)
AR (1) AR020030A1 (es)
AT (1) ATE392427T1 (es)
AU (1) AU772283B2 (es)
BG (1) BG106150A (es)
BR (1) BR0011300A (es)
CA (1) CA2372206C (es)
CZ (1) CZ20014120A3 (es)
DE (1) DE60038610T2 (es)
DK (1) DK1189912T3 (es)
DZ (1) DZ3043A1 (es)
EA (1) EA003417B1 (es)
ES (1) ES2302689T3 (es)
GT (1) GT200000072A (es)
HK (1) HK1045521B (es)
HN (1) HN2000000056A (es)
HR (1) HRP20010849A2 (es)
HU (1) HUP0201341A3 (es)
IL (2) IL145946A0 (es)
IS (1) IS6127A (es)
MA (1) MA26735A1 (es)
MX (1) MXPA01011914A (es)
MY (1) MY133397A (es)
NO (1) NO320195B1 (es)
NZ (1) NZ514765A (es)
OA (1) OA11876A (es)
PA (1) PA8495001A1 (es)
PE (1) PE20010151A1 (es)
PL (1) PL353316A1 (es)
PT (1) PT1189912E (es)
SK (1) SK16472001A3 (es)
TN (1) TNSN00103A1 (es)
TW (1) TWI225066B (es)
UA (1) UA67842C2 (es)
UY (1) UY26144A1 (es)
WO (1) WO2000069874A1 (es)
YU (1) YU76601A (es)
ZA (1) ZA200109420B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
MXPA02007305A (es) 2000-01-27 2002-11-29 Pfizer Prod Inc Composiciones antiboticas de azalida.
JP4104463B2 (ja) * 2001-04-27 2008-06-18 ファイザー・プロダクツ・インク 4’’−置換された−9−デオキソ−9a−アザ−9a−ホモエリスロマイシン誘導体を製造するための方法
EP1435359A1 (en) * 2002-12-31 2004-07-07 Alembic Limited A process for the purification of roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
MA32997B1 (fr) * 2009-01-30 2012-01-02 Glaxo Group Ltd Macrolide anti-inflammatoire
EP2402355A1 (en) * 2010-07-01 2012-01-04 Novartis AG Crystalline anhydrous forms II and III of Tulathromycin
WO2013013834A1 (en) 2011-07-27 2013-01-31 Farma Grs, D.O.O. New crystalline forms of tulathromycin
CN106008622A (zh) * 2016-08-02 2016-10-12 海门慧聚药业有限公司 泰拉霉素新晶型及其制备
CN109942652B (zh) * 2017-12-21 2022-04-26 洛阳惠中兽药有限公司 一种莱柯霉素晶型ⅰ及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO107257B1 (ro) * 1987-07-09 1993-10-30 Pfizer Procedeu de obtinere a unui dihidrat de azitromicina, cristalin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5844105A (en) * 1996-07-29 1998-12-01 Abbott Laboratories Preparation of crystal form II of clarithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
HRP20010849A2 (en) 2003-04-30
IL145946A (en) 2007-06-17
KR100474229B1 (ko) 2005-03-08
KR20020007415A (ko) 2002-01-26
CN1351607A (zh) 2002-05-29
AP2001002325A0 (en) 2001-12-31
HK1045521A1 (en) 2002-11-29
NO20015598D0 (no) 2001-11-16
IL145946A0 (en) 2002-07-25
TNSN00103A1 (fr) 2005-11-10
GT200000072A (es) 2001-11-08
SK16472001A3 (sk) 2003-02-04
HK1045521B (zh) 2005-12-09
ES2302689T3 (es) 2008-08-01
HN2000000056A (es) 2001-02-02
EP1189912A1 (en) 2002-03-27
TWI225066B (en) 2004-12-11
MXPA01011914A (es) 2002-05-06
CA2372206A1 (en) 2000-11-23
HUP0201341A3 (en) 2003-03-28
EP1189912B1 (en) 2008-04-16
CA2372206C (en) 2006-01-10
CZ20014120A3 (cs) 2003-01-15
NO320195B1 (no) 2005-11-14
UA67842C2 (uk) 2004-07-15
EA003417B1 (ru) 2003-04-24
DE60038610T2 (de) 2009-06-25
YU76601A (sh) 2004-09-03
DE60038610D1 (de) 2008-05-29
JP2002544283A (ja) 2002-12-24
NO20015598L (no) 2002-01-08
CN1203084C (zh) 2005-05-25
BR0011300A (pt) 2002-02-26
US6583274B1 (en) 2003-06-24
DZ3043A1 (fr) 2004-03-27
MY133397A (en) 2007-11-30
EA200100984A1 (ru) 2002-06-27
UY26144A1 (es) 2000-12-29
OA11876A (en) 2006-03-27
IS6127A (is) 2001-10-26
BG106150A (bg) 2002-05-31
AU3572900A (en) 2000-12-05
ZA200109420B (en) 2002-11-15
PA8495001A1 (es) 2002-02-21
AU772283B2 (en) 2004-04-22
AR020030A1 (es) 2002-03-27
HUP0201341A2 (en) 2002-08-28
WO2000069874A1 (en) 2000-11-23
ATE392427T1 (de) 2008-05-15
PT1189912E (pt) 2008-05-16
PL353316A1 (en) 2003-11-17
NZ514765A (en) 2004-05-28
JP3897983B2 (ja) 2007-03-28
PE20010151A1 (es) 2001-02-08
MA26735A1 (fr) 2004-12-20

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