PE20001036A1 - Tabletas bioadhesivas para hidratacion progresiva y metodos para su elaboracion y uso - Google Patents
Tabletas bioadhesivas para hidratacion progresiva y metodos para su elaboracion y usoInfo
- Publication number
- PE20001036A1 PE20001036A1 PE1999000855A PE00085599A PE20001036A1 PE 20001036 A1 PE20001036 A1 PE 20001036A1 PE 1999000855 A PE1999000855 A PE 1999000855A PE 00085599 A PE00085599 A PE 00085599A PE 20001036 A1 PE20001036 A1 PE 20001036A1
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- PE
- Peru
- Prior art keywords
- preparation
- methods
- agronasist
- refers
- composition
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A UNA TABLETA BIOADHESIVA DE LIBERACION SOSTENIDA PARA HIDRATACION PROGRESIVA QUE COMPRENDE: a) HASTA 50% DE PRINCIPIO ACTIVO TAL COMO GLICOPROTEINAS, PROTEINAS, HORMONAS SEXUALES (TESTOSTERONA 1%-30%), ANTIHORMONAS, NITRATOS, ß-AGONISTAS, ß-ANTAGONISTAS, OPIACEOS, ANTIDEPRESIVOS, INHIBIDORES DE LA REDUCTASA DE HMG CoA, ANTIHISTAMINAS, INHIBIDORES DE LA ECA, PROSTAGLANDINAS, O UN PRINCIPIO QUE ES DEGRADADO O METABOLIZADO POR HUMEDAD, ENZIMAS O pH; b)5%-50% DE CELULOSA; c)DE 5% A 25% DE ALMIDON; d)DE 1% A 50% DE LACTOSA; e)DE 5% A 10% DE UN POLIMERO POLICARBOXILICO; f)DE 1% A 75% DE UN POLIMERO HIDROSOLUBLE; g)1% DE SILICE; h)DE 0,5% A 1% DE ESTEARATO DE MAGNESIO. TAMBIEN SE REFIERE A UNA COMPOSICION QUE COMPRENDE ADEMAS DE 2% A 30% DE UN LIGANTE. LA COMPOSICION PUEDE SER UTIL PARA EL TRATAMIENTO O PREVENCION DE LA ISQUEMIA, ENFERMEDAD DE ALZHEIMER
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9784398P | 1998-08-25 | 1998-08-25 | |
US09/379,310 US6248358B1 (en) | 1998-08-25 | 1999-08-23 | Bioadhesive progressive hydration tablets and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20001036A1 true PE20001036A1 (es) | 2000-10-12 |
Family
ID=22265404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1999000855A PE20001036A1 (es) | 1998-08-25 | 1999-08-25 | Tabletas bioadhesivas para hidratacion progresiva y metodos para su elaboracion y uso |
Country Status (26)
Country | Link |
---|---|
US (1) | US6248358B1 (es) |
EP (1) | EP1105104B1 (es) |
JP (2) | JP5411398B2 (es) |
KR (1) | KR100716702B1 (es) |
CN (2) | CN1879608A (es) |
AR (1) | AR036972A1 (es) |
AT (1) | ATE306253T1 (es) |
AU (1) | AU754880B2 (es) |
BR (1) | BR9913239B1 (es) |
CA (1) | CA2341375C (es) |
DE (1) | DE69927694T2 (es) |
DK (1) | DK1105104T3 (es) |
ES (1) | ES2251220T3 (es) |
HK (1) | HK1034895A1 (es) |
HU (1) | HU226591B1 (es) |
IL (1) | IL141445A (es) |
MA (1) | MA24964A1 (es) |
MX (1) | MXPA01002007A (es) |
MY (2) | MY125919A (es) |
NO (1) | NO331255B1 (es) |
NZ (1) | NZ509963A (es) |
PE (1) | PE20001036A1 (es) |
RU (1) | RU2227022C2 (es) |
UA (1) | UA78967C2 (es) |
WO (1) | WO2000010536A1 (es) |
ZA (1) | ZA995445B (es) |
Families Citing this family (46)
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US7803392B2 (en) * | 2000-12-27 | 2010-09-28 | University Of Kentucky Research Foundation | pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules |
WO2002087552A2 (en) * | 2001-05-01 | 2002-11-07 | Mcgill University | Androgen-mediated neuroprotection and uses thereof |
CN101327326A (zh) * | 2001-10-29 | 2008-12-24 | 哥伦比亚实验室(百慕大群岛)有限公司 | 阴道给药治疗骨盆痛和不孕症的抗节律障碍剂 |
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DE69510894T2 (de) | 1994-06-16 | 2000-02-03 | Pharmacia & Upjohn S.P.A., Mailand | Verfahren zur Herstellung mucoadhesiver Stärke |
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-
1999
- 1999-08-23 US US09/379,310 patent/US6248358B1/en not_active Expired - Lifetime
- 1999-08-24 CA CA002341375A patent/CA2341375C/en not_active Expired - Fee Related
- 1999-08-24 CN CNA2005101375941A patent/CN1879608A/zh active Pending
- 1999-08-24 AT AT99942454T patent/ATE306253T1/de active
- 1999-08-24 CN CNB998122009A patent/CN1259903C/zh not_active Expired - Fee Related
- 1999-08-24 DK DK99942454T patent/DK1105104T3/da active
- 1999-08-24 BR BRPI9913239-7A patent/BR9913239B1/pt not_active IP Right Cessation
- 1999-08-24 HU HU0103218A patent/HU226591B1/hu not_active IP Right Cessation
- 1999-08-24 RU RU2001107846/15A patent/RU2227022C2/ru not_active IP Right Cessation
- 1999-08-24 DE DE69927694T patent/DE69927694T2/de not_active Expired - Lifetime
- 1999-08-24 WO PCT/US1999/019260 patent/WO2000010536A1/en active IP Right Grant
- 1999-08-24 AU AU55826/99A patent/AU754880B2/en not_active Ceased
- 1999-08-24 NZ NZ509963A patent/NZ509963A/en not_active IP Right Cessation
- 1999-08-24 ES ES99942454T patent/ES2251220T3/es not_active Expired - Lifetime
- 1999-08-24 JP JP2000565858A patent/JP5411398B2/ja not_active Expired - Fee Related
- 1999-08-24 KR KR1020017002347A patent/KR100716702B1/ko not_active IP Right Cessation
- 1999-08-24 UA UA2001031967A patent/UA78967C2/uk unknown
- 1999-08-24 MX MXPA01002007A patent/MXPA01002007A/es not_active IP Right Cessation
- 1999-08-24 EP EP99942454A patent/EP1105104B1/en not_active Expired - Lifetime
- 1999-08-24 IL IL14144599A patent/IL141445A/xx not_active IP Right Cessation
- 1999-08-25 AR ARP990104253A patent/AR036972A1/es active IP Right Grant
- 1999-08-25 PE PE1999000855A patent/PE20001036A1/es not_active Application Discontinuation
- 1999-08-25 MA MA25744A patent/MA24964A1/fr unknown
- 1999-08-25 MY MYPI99003649A patent/MY125919A/en unknown
- 1999-08-25 ZA ZA9905445A patent/ZA995445B/xx unknown
-
2000
- 2000-06-20 MY MYPI20002772A patent/MY133365A/en unknown
-
2001
- 2001-02-23 NO NO20010919A patent/NO331255B1/no not_active IP Right Cessation
- 2001-07-13 HK HK01104891A patent/HK1034895A1/xx not_active IP Right Cessation
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2010
- 2010-07-02 JP JP2010151682A patent/JP2010248231A/ja active Pending
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