OA13234A - Modified human IGF-1R antibodies. - Google Patents
Modified human IGF-1R antibodies. Download PDFInfo
- Publication number
- OA13234A OA13234A OA1200600046A OA1200600046A OA13234A OA 13234 A OA13234 A OA 13234A OA 1200600046 A OA1200600046 A OA 1200600046A OA 1200600046 A OA1200600046 A OA 1200600046A OA 13234 A OA13234 A OA 13234A
- Authority
- OA
- OAPI
- Prior art keywords
- antibody
- igf
- human
- antigen
- amino acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49520003P | 2003-08-13 | 2003-08-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
OA13234A true OA13234A (en) | 2006-12-13 |
Family
ID=34193291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA1200600046A OA13234A (en) | 2003-08-13 | 2004-08-03 | Modified human IGF-1R antibodies. |
Country Status (37)
Country | Link |
---|---|
US (2) | US7371378B2 (fr) |
EP (1) | EP1656391B1 (fr) |
JP (1) | JP4638870B2 (fr) |
KR (1) | KR100825156B1 (fr) |
CN (1) | CN1835975B (fr) |
AP (1) | AP2006003510A0 (fr) |
AR (1) | AR045247A1 (fr) |
AT (1) | ATE484525T1 (fr) |
AU (1) | AU2004265152A1 (fr) |
BR (1) | BRPI0413466A (fr) |
CA (1) | CA2535071A1 (fr) |
CL (1) | CL2004002035A1 (fr) |
CR (1) | CR8233A (fr) |
DE (1) | DE602004029581D1 (fr) |
DK (1) | DK1656391T3 (fr) |
EA (1) | EA200600234A1 (fr) |
EC (1) | ECSP066359A (fr) |
ES (1) | ES2351395T3 (fr) |
GT (1) | GT200400158A (fr) |
IL (1) | IL173273A (fr) |
IS (1) | IS8266A (fr) |
MA (1) | MA27988A1 (fr) |
MX (1) | MXPA06001634A (fr) |
NL (1) | NL1026829C2 (fr) |
NO (1) | NO20060542L (fr) |
OA (1) | OA13234A (fr) |
PA (1) | PA8608801A1 (fr) |
PE (1) | PE20050339A1 (fr) |
PL (1) | PL1656391T3 (fr) |
PT (1) | PT1656391E (fr) |
RS (1) | RS20060099A (fr) |
TN (1) | TNSN06050A1 (fr) |
TW (1) | TWI294915B (fr) |
UA (1) | UA85058C2 (fr) |
UY (1) | UY28464A1 (fr) |
WO (1) | WO2005016967A2 (fr) |
ZA (1) | ZA200601231B (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX337162B (es) * | 2001-01-05 | 2016-02-15 | Pfizer | Anticuerpos contra el receptor del factor de crecimiento similar a insulina. |
US7217796B2 (en) | 2002-05-24 | 2007-05-15 | Schering Corporation | Neutralizing human anti-IGFR antibody |
ES2527871T3 (es) * | 2003-05-01 | 2015-02-02 | Imclone Llc | Anticuerpos completamente humanos dirigidos contra el receptor del factor de crecimiento 1 similar a la insulina humana |
EA200600234A1 (ru) * | 2003-08-13 | 2006-08-25 | Пфайзер Продактс Инк. | Модифицированные igf - 1r антитела человека |
ATE514783T1 (de) | 2003-11-12 | 2011-07-15 | Schering Corp | Plasmidsystem zur expression mehrerer gene |
PE20050928A1 (es) | 2003-11-21 | 2005-11-08 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti-igfr1 |
EP2335727A3 (fr) * | 2004-07-16 | 2011-09-28 | Pfizer Products Inc. | Traitement combiné pour malignités non hématologiques par anticorps anti-IGF-1R |
FR2873699B1 (fr) * | 2004-07-29 | 2009-08-21 | Pierre Fabre Medicament Sa | Nouveaux anticorps anti igf ir rt leurs utilisations |
CA2589885A1 (fr) | 2004-12-03 | 2006-06-08 | Schering Corporation | Biomarqueurs pour la preselection de patients pour la therapie contre le recepteur du facteur de croissance semblable a l'insuline 1 |
MY146381A (en) | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
GB0500417D0 (en) * | 2005-01-10 | 2005-02-16 | Cambridge Antibody Tech | Method of mutagenesis |
JP4875064B2 (ja) * | 2005-04-15 | 2012-02-15 | シェーリング コーポレイション | 癌を処置または予防するための方法および組成物 |
KR20080019249A (ko) * | 2005-06-15 | 2008-03-03 | 쉐링 코포레이션 | 안정한 항체 제형 |
EP1909819A4 (fr) | 2005-06-17 | 2010-02-17 | Imclone Llc | Antagonistes de recepteur pour le traitement de cancer osseux metastatique |
FR2888850B1 (fr) | 2005-07-22 | 2013-01-11 | Pf Medicament | Nouveaux anticorps anti-igf-ir et leurs applications |
AP2008004569A0 (en) * | 2006-02-03 | 2008-08-31 | Imclone Systems Inc | IGR-IR antagonists as adjuvants for treatment of prostrate cancer |
EP1998806A1 (fr) * | 2006-03-28 | 2008-12-10 | F. Hoffmann-Roche AG | Formulation d'anticorps monoclonal humain anti-igf-1r |
US7846724B2 (en) | 2006-04-11 | 2010-12-07 | Hoffmann-La Roche Inc. | Method for selecting CHO cell for production of glycosylated antibodies |
PT2027470E (pt) | 2006-06-02 | 2013-01-28 | Pfizer Prod Inc | Ensaio de células tumorais circulantes |
AR064464A1 (es) * | 2006-12-22 | 2009-04-01 | Genentech Inc | Anticuerpos anti - receptor del factor de crecimiento insulinico |
GB0702888D0 (en) * | 2007-02-14 | 2007-03-28 | Glaxo Group Ltd | Novel Antibodies |
AU2012203443B2 (en) * | 2007-03-02 | 2014-03-06 | Amgen Inc. | Methods and compositions for treating tumor diseases |
CA2679548C (fr) * | 2007-03-02 | 2015-01-27 | Amgen Inc. | Procedes et compositions permettant de traiter des maladies tumorales |
EP2136839A4 (fr) * | 2007-03-22 | 2010-04-07 | Imclone Llc | Formulations d'anticorps stables |
EP2145021A2 (fr) | 2007-05-17 | 2010-01-20 | Bristol-Myers Squibb Company | Biomarqueurs et procédés pour déterminer la sensibilité de modulateurs de récepteur de facteur de croissance de type 1 semblable à l'insuline |
ES2388017T3 (es) | 2007-12-21 | 2012-10-05 | Roche Glycart Ag | Ensayo de estabilidad de anticuerpos |
CA2718918A1 (fr) * | 2008-03-25 | 2009-11-26 | Schering Corporation | Procedes de traitement ou de prevention de cancer colorectal |
JP2011519868A (ja) * | 2008-05-05 | 2011-07-14 | シェーリング コーポレイション | 癌を処置するための化学療法剤の連続投与 |
US20110313134A1 (en) * | 2008-11-06 | 2011-12-22 | Alexion Pharmaceuticals, Inc. | Engineered antibodies with reduced immunogenicity and methods of making |
JP2012518657A (ja) | 2009-02-25 | 2012-08-16 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 併用抗癌治療 |
EP2236139A1 (fr) | 2009-03-31 | 2010-10-06 | F. Hoffmann-La Roche AG | Thérapie combinée d'erlotinibe avec un anticorps anti-IGF-1R, qui n'inhibe pas la liaison d'insuline dans le récepteur d'insuline |
WO2010146059A2 (fr) | 2009-06-16 | 2010-12-23 | F. Hoffmann-La Roche Ag | Biomarqueurs pour une thérapie par inhibiteur d'igf-1r |
TWI513465B (zh) | 2009-06-25 | 2015-12-21 | Regeneron Pharma | 以dll4拮抗劑與化學治療劑治療癌症之方法 |
US20110117087A1 (en) | 2009-10-26 | 2011-05-19 | Reinhard Franze | Method for the production of a glycosylated immunoglobulin |
EP2494070A2 (fr) | 2009-10-30 | 2012-09-05 | Bristol-Myers Squibb Company | Méthodes pour traiter un cancer chez des patients présentant une résistance à l'inhibiteur d'igf-1r |
AU2014262201B2 (en) * | 2009-12-23 | 2016-09-15 | Novartis Ag | Method for decreasing immunogenicity |
JP5914353B2 (ja) * | 2009-12-23 | 2016-05-11 | エスバテック − ア ノバルティス カンパニー エルエルシー | 免疫原性を減少させるための方法 |
WO2011101328A2 (fr) | 2010-02-18 | 2011-08-25 | Roche Glycart Ag | Traitement au moyen d'un anticorps anti-egfr de la classe igg humanisé et d'un anticorps contre le récepteur du facteur de croissance 1 analogue à l'insuline |
WO2011161119A1 (fr) | 2010-06-22 | 2011-12-29 | F. Hoffmann-La Roche Ag | Anticorps contre le récepteur du facteur de croissance insulinique i et ses utilisations |
JP5913307B2 (ja) | 2010-07-12 | 2016-04-27 | コヴェックス・テクノロジーズ・アイルランド・リミテッド | 多機能性抗体複合体 |
CA2825894C (fr) | 2011-02-02 | 2021-11-30 | Amgen Inc. | Pronostic de cancer au moyen de biomarqueur en circulation |
TR201905909T4 (tr) | 2011-04-19 | 2019-05-21 | Pfizer | Kanser tedavisi için anti-4-1bb antikorlarının ve adcc indükleyici antikorların kombinasyonları. |
EP2766497A1 (fr) | 2011-10-13 | 2014-08-20 | Bristol-Myers Squibb Company | Procédés de sélection et de traitement du cancer chez des patients au moyen d'inhibiteurs de l'igf-1r/ir |
JP6413127B2 (ja) | 2012-01-09 | 2018-10-31 | コヴェックス・テクノロジーズ・アイルランド・リミテッド | 変異抗体およびそのコンジュゲーション |
EP2631653A1 (fr) | 2012-02-24 | 2013-08-28 | Charité - Universitätsmedizin Berlin | Identification de modulateurs de liaison des propriétés d'anticorps réactifs avec un élément de la famille des récepteurs de l'insuline |
WO2013152252A1 (fr) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Polythérapie antinéoplasique |
CA2888211A1 (fr) * | 2012-11-06 | 2014-05-15 | Medimmune, Llc | Polytherapies a l'aide de molecules de liaison anti-pseudomonas psl et pcrv |
PE20151807A1 (es) | 2013-04-29 | 2015-12-02 | Hoffmann La Roche | Anticuerpos modificados de union a fcrn humano y metodo de utilizacion |
CN103319598B (zh) * | 2013-05-13 | 2014-10-22 | 杭州德同生物技术有限公司 | 抗胰岛素样生长因子-1受体抗体及其编码基因和应用 |
CN105916880B (zh) | 2014-01-15 | 2020-01-17 | 豪夫迈·罗氏有限公司 | 具有改善的蛋白A结合作用的Fc区变体 |
US20200407445A1 (en) * | 2017-07-27 | 2020-12-31 | Iteos Therapeutics Sa | Anti-tigit antibodies |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6054561A (en) * | 1984-02-08 | 2000-04-25 | Chiron Corporation | Antigen-binding sites of antibody molecules specific for cancer antigens |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
US6657103B1 (en) * | 1990-01-12 | 2003-12-02 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
US5863949A (en) | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
WO1996033172A1 (fr) | 1995-04-20 | 1996-10-24 | Pfizer Inc. | Derives d'acide hydroxamique arylsufonyle en tant qu'inhibiteurs de mmp et de tnf |
EP1978033A3 (fr) | 1995-04-27 | 2008-12-24 | Amgen Fremont Inc. | Anticorps humains dérivés à partir de xénosouris immunisée |
IL118626A0 (en) * | 1996-06-11 | 1996-10-16 | Xtl Biopharmaceuticals Limited | Anti HBV antibody |
EA199900036A1 (ru) | 1996-07-18 | 1999-06-24 | Пфайзер Инк | Ингибиторы металлопротеаз матрикса на основе фосфинатов, фармацевтическая композиция, способ лечения |
JP2000501423A (ja) | 1996-08-23 | 2000-02-08 | ファイザー インク. | アリールスルホニルアミノヒドロキサム酸誘導体 |
JP2002515511A (ja) | 1998-05-15 | 2002-05-28 | イムクローン システムズ インコーポレイティド | 放射線及び成長因子レセプター・チロシン・キナーゼのインヒビターを使用するヒト腫瘍の治療 |
EE05627B1 (et) * | 1998-12-23 | 2013-02-15 | Pfizer Inc. | CTLA-4 vastased inimese monoklonaalsed antikehad |
MY145191A (en) | 1999-03-25 | 2011-12-30 | Abbott Gmbh & Co Kg | Human antibodies that bind human il-12 and methods for producing |
ES1042735Y (es) | 1999-04-07 | 2000-02-16 | Martinez Fernando Martinez | Vehiculo tripersonal de accionamiento a pedales. |
US20030165502A1 (en) | 2000-06-13 | 2003-09-04 | City Of Hope | Single-chain antibodies against human insulin-like growth factor I receptor: expression, purification, and effect on tumor growth |
DE10033869C2 (de) | 2000-07-12 | 2003-07-31 | Karlsruhe Forschzent | HTS-Kryomagnet und Aufmagnetisierungsverfahren |
MX337162B (es) * | 2001-01-05 | 2016-02-15 | Pfizer | Anticuerpos contra el receptor del factor de crecimiento similar a insulina. |
BR0207283A (pt) | 2001-02-19 | 2004-08-17 | Merck Patent Gmbh | Anticorpos anti-egfr modificados com imunogenicidade reduzida |
PT1461359E (pt) | 2002-01-18 | 2007-06-29 | Pf Medicament | Anticorpos anti-igf-ir e suas aplicações |
EP1505075B1 (fr) | 2002-04-30 | 2009-10-07 | Kyowa Hakko Kirin Co., Ltd. | Anticorps pour facteur de croissance humain semblable a l'insuline |
US7217796B2 (en) | 2002-05-24 | 2007-05-15 | Schering Corporation | Neutralizing human anti-IGFR antibody |
GB0212303D0 (en) | 2002-05-28 | 2002-07-10 | Isis Innovation | Molecular targetting of IGF-1 receptor |
US7538195B2 (en) | 2002-06-14 | 2009-05-26 | Immunogen Inc. | Anti-IGF-I receptor antibody |
PL378812A1 (pl) | 2003-02-13 | 2006-05-29 | Pfizer Products Inc. | Zastosowania przeciwciał przeciw receptorowi insulinopodobnego czynnika wzrostowego I |
JP2007528201A (ja) | 2003-03-14 | 2007-10-11 | ファルマシア・コーポレーション | 癌治療のためのigf−i受容体に対する抗体 |
ATE549359T1 (de) | 2003-04-02 | 2012-03-15 | Hoffmann La Roche | Antikörper gegen den insulinähnlichen wachstumsfaktor i-rezeptor und deren verwendungen |
EA200600234A1 (ru) * | 2003-08-13 | 2006-08-25 | Пфайзер Продактс Инк. | Модифицированные igf - 1r антитела человека |
-
2004
- 2004-08-03 EA EA200600234A patent/EA200600234A1/ru unknown
- 2004-08-03 CA CA002535071A patent/CA2535071A1/fr not_active Abandoned
- 2004-08-03 MX MXPA06001634A patent/MXPA06001634A/es unknown
- 2004-08-03 KR KR1020067002957A patent/KR100825156B1/ko not_active IP Right Cessation
- 2004-08-03 DE DE602004029581T patent/DE602004029581D1/de active Active
- 2004-08-03 BR BRPI0413466-4A patent/BRPI0413466A/pt not_active IP Right Cessation
- 2004-08-03 PL PL04744197T patent/PL1656391T3/pl unknown
- 2004-08-03 CN CN2004800230991A patent/CN1835975B/zh not_active Expired - Fee Related
- 2004-08-03 WO PCT/IB2004/002555 patent/WO2005016967A2/fr active Application Filing
- 2004-08-03 RS YUP-2006/0099A patent/RS20060099A/sr unknown
- 2004-08-03 PT PT04744197T patent/PT1656391E/pt unknown
- 2004-08-03 AT AT04744197T patent/ATE484525T1/de active
- 2004-08-03 AU AU2004265152A patent/AU2004265152A1/en not_active Abandoned
- 2004-08-03 UA UAA200601349A patent/UA85058C2/ru unknown
- 2004-08-03 DK DK04744197.7T patent/DK1656391T3/da active
- 2004-08-03 AP AP2006003510A patent/AP2006003510A0/xx unknown
- 2004-08-03 OA OA1200600046A patent/OA13234A/en unknown
- 2004-08-03 JP JP2006523070A patent/JP4638870B2/ja not_active Expired - Fee Related
- 2004-08-03 ES ES04744197T patent/ES2351395T3/es active Active
- 2004-08-03 EP EP04744197A patent/EP1656391B1/fr active Active
- 2004-08-09 PE PE2004000773A patent/PE20050339A1/es not_active Application Discontinuation
- 2004-08-10 CL CL200402035A patent/CL2004002035A1/es unknown
- 2004-08-11 UY UY28464A patent/UY28464A1/es not_active Application Discontinuation
- 2004-08-11 AR ARP040102870A patent/AR045247A1/es active IP Right Grant
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- 2004-08-12 GT GT200400158A patent/GT200400158A/es unknown
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2006
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- 2006-02-13 TN TNP2006000050A patent/TNSN06050A1/fr unknown
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2008
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