OA12737A - Crystalline form of a ribofuranosyluronamide derivative; a human adenosine A2A receptor agonist. - Google Patents

Crystalline form of a ribofuranosyluronamide derivative; a human adenosine A2A receptor agonist. Download PDF

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Publication number
OA12737A
OA12737A OA1200400163A OA1200400163A OA12737A OA 12737 A OA12737 A OA 12737A OA 1200400163 A OA1200400163 A OA 1200400163A OA 1200400163 A OA1200400163 A OA 1200400163A OA 12737 A OA12737 A OA 12737A
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OA
OAPI
Prior art keywords
ethyl
ribofuranosyluronamide
carboxamide
purine
pyridyl
Prior art date
Application number
OA1200400163A
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English (en)
Inventor
Terence Vernon Silk
Julian Duncan Smith
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of OA12737A publication Critical patent/OA12737A/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

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  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nanotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
OA1200400163A 2001-12-06 2002-11-27 Crystalline form of a ribofuranosyluronamide derivative; a human adenosine A2A receptor agonist. OA12737A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0129273.9A GB0129273D0 (en) 2001-12-06 2001-12-06 Crystalline drug form

Publications (1)

Publication Number Publication Date
OA12737A true OA12737A (en) 2006-06-29

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ID=9927165

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200400163A OA12737A (en) 2001-12-06 2002-11-27 Crystalline form of a ribofuranosyluronamide derivative; a human adenosine A2A receptor agonist.

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US (3) US20030144243A1 (pt)
EP (1) EP1456219B1 (pt)
JP (1) JP4184279B2 (pt)
KR (1) KR100554333B1 (pt)
CN (1) CN100381454C (pt)
AP (1) AP2004003056A0 (pt)
AR (2) AR038547A1 (pt)
AT (1) ATE364615T1 (pt)
AU (2) AU2002351056A1 (pt)
BR (1) BR0214747A (pt)
CA (1) CA2468847C (pt)
CY (1) CY1106822T1 (pt)
DE (1) DE60220713T2 (pt)
DK (1) DK1456219T3 (pt)
EA (1) EA006857B1 (pt)
EC (1) ECSP045141A (pt)
ES (1) ES2286303T3 (pt)
GB (1) GB0129273D0 (pt)
GT (2) GT200200256A (pt)
HK (1) HK1071143A1 (pt)
HN (1) HN2002000352A (pt)
HR (1) HRP20040516A2 (pt)
HU (1) HUP0700046A2 (pt)
IL (2) IL162101A0 (pt)
IS (1) IS7279A (pt)
MA (1) MA27151A1 (pt)
MX (1) MXPA04005505A (pt)
NO (1) NO20042837L (pt)
NZ (1) NZ533053A (pt)
OA (1) OA12737A (pt)
PA (2) PA8560301A1 (pt)
PE (2) PE20030722A1 (pt)
PL (1) PL370971A1 (pt)
PT (1) PT1456219E (pt)
RS (1) RS49504A (pt)
SV (1) SV2004001425A (pt)
TN (1) TNSN04103A1 (pt)
TW (2) TW200301129A (pt)
UY (1) UY27568A1 (pt)
WO (2) WO2003047597A1 (pt)
ZA (1) ZA200403967B (pt)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
US20030225089A1 (en) * 2002-04-10 2003-12-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors
DE10345065A1 (de) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
PE20060272A1 (es) 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
WO2021084791A1 (ja) * 2019-10-28 2021-05-06 有限会社イムノ アデノシンａ２ａ受容体を標的とする組成物
CN115400140B (zh) * 2022-01-27 2024-02-20 宁波熙健医药科技有限公司 呋喃核糖基吡啶衍生物用于预防或治疗癫痫或惊厥的用途

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US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
GB9913932D0 (en) * 1999-06-15 1999-08-18 Pfizer Ltd Purine derivatives
WO2001020089A1 (fr) 1999-09-10 2001-03-22 Maeda Corporation Structure de beton et procede de construction
GB0003960D0 (en) * 2000-02-18 2000-04-12 Pfizer Ltd Purine derivatives
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
GB0009605D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
GB0009583D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
TWI227240B (en) * 2000-06-06 2005-02-01 Pfizer 2-aminocarbonyl-9H-purine derivatives
AU5800800A (en) 2000-07-26 2002-02-05 Swisscom Mobile Ag Method for the assembly of a mobile radio network base station and connection ofthe base station to the network
WO2002096462A1 (en) * 2001-05-25 2002-12-05 Pfizer Inc. An adenosine a2a receptor agonist and an anticholinergic agent in combination for treating obstructive airways diseases

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PE20030822A1 (es) 2003-10-04
ES2286303T3 (es) 2007-12-01
IS7279A (is) 2004-05-21
CA2468847A1 (en) 2003-06-12
EP1456219B1 (en) 2007-06-13
PT1456219E (pt) 2007-08-03
WO2003047597A1 (en) 2003-06-12
MXPA04005505A (es) 2005-06-03
HK1071143A1 (en) 2005-07-08
DE60220713T2 (de) 2008-03-06
IL162101A (en) 2010-04-29
HRP20040516A2 (en) 2004-10-31
EA200400638A1 (ru) 2004-10-28
CN1599745A (zh) 2005-03-23
GB0129273D0 (en) 2002-01-23
EP1456219A1 (en) 2004-09-15
ECSP045141A (es) 2004-07-23
ZA200403967B (en) 2006-05-31
CY1106822T1 (el) 2012-05-23
KR20050058272A (ko) 2005-06-16
ATE364615T1 (de) 2007-07-15
TNSN04103A1 (fr) 2006-06-01
RS49504A (en) 2006-10-27
PL370971A1 (en) 2005-06-13
US20050085437A1 (en) 2005-04-21
CA2468847C (en) 2008-10-21
AR037633A1 (es) 2004-11-17
AU2002351056A1 (en) 2003-06-17
CN100381454C (zh) 2008-04-16
NO20042837L (no) 2004-08-24
UY27568A1 (es) 2003-07-31
EA006857B1 (ru) 2006-04-28
TW200301130A (en) 2003-07-01
US7022727B2 (en) 2006-04-04
WO2003048180A1 (en) 2003-06-12
IL162101A0 (en) 2005-11-20
PE20030722A1 (es) 2003-08-29
US20030144243A1 (en) 2003-07-31
PA8560501A1 (es) 2003-09-17
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