OA11112A - Process for preparing 2-azadihydroxybicycloÄ2.2.1Üheptane compounds and the l-tartaric acid salt of the compound - Google Patents

Process for preparing 2-azadihydroxybicycloÄ2.2.1Üheptane compounds and the l-tartaric acid salt of the compound Download PDF

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Publication number
OA11112A
OA11112A OA9900080A OA9900080A OA11112A OA 11112 A OA11112 A OA 11112A OA 9900080 A OA9900080 A OA 9900080A OA 9900080 A OA9900080 A OA 9900080A OA 11112 A OA11112 A OA 11112A
Authority
OA
OAPI
Prior art keywords
compound
formula
mol
azadihydroxybicyclo
diastereomer
Prior art date
Application number
OA9900080A
Other languages
English (en)
Inventor
Thierry Durand
Denis Largeau
Patrick Leon
Michael O'brien
Matthew Powers
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of OA11112A publication Critical patent/OA11112A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
OA9900080A 1996-10-16 1999-04-09 Process for preparing 2-azadihydroxybicycloÄ2.2.1Üheptane compounds and the l-tartaric acid salt of the compound OA11112A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/732,024 US5684159A (en) 1995-05-30 1996-10-16 L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds

Publications (1)

Publication Number Publication Date
OA11112A true OA11112A (en) 2003-04-04

Family

ID=24941881

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9900080A OA11112A (en) 1996-10-16 1999-04-09 Process for preparing 2-azadihydroxybicycloÄ2.2.1Üheptane compounds and the l-tartaric acid salt of the compound

Country Status (22)

Country Link
US (4) US5684159A (hu)
EP (1) EP0934268A4 (hu)
JP (1) JP2001502329A (hu)
KR (1) KR20000049195A (hu)
CN (2) CN1094927C (hu)
AP (1) AP942A (hu)
AU (1) AU721965B2 (hu)
BG (2) BG64701B1 (hu)
BR (1) BR9711910A (hu)
CA (1) CA2268652A1 (hu)
CZ (1) CZ291387B6 (hu)
EA (3) EA002438B1 (hu)
HK (1) HK1022475A1 (hu)
HU (1) HUP9903583A3 (hu)
IL (1) IL129231A (hu)
NO (2) NO320332B1 (hu)
OA (1) OA11112A (hu)
PL (1) PL332827A1 (hu)
SK (1) SK43799A3 (hu)
UA (1) UA52702C2 (hu)
WO (1) WO1998016510A1 (hu)
ZA (1) ZA979268B (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds
DE69823786T2 (de) * 1997-12-25 2005-04-28 KURARAY CO., LTD, Kurashiki Verfahren zur Herstellung und Verfahren zum Kristallisieren von 2-Azabicyclo(2.2.1)hept-5-en-3-on
TW396337B (en) * 1998-02-13 2000-07-01 Mediatek Inc The automatic regulating device of cdrom optimum focusing spot and the method thereof
US5986100A (en) 1998-04-02 1999-11-16 Crooks; Peter Anthony Pharmaceutical compositions and methods for use
US5952339A (en) * 1998-04-02 1999-09-14 Bencherif; Merouane Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release
US6057446A (en) 1998-04-02 2000-05-02 Crooks; Peter Anthony Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds
SI1140933T1 (en) 1998-12-31 2005-02-28 Aventis Pharmaceuticals Inc. Process for preparing n6-substituted deaza-adenosine derivatives
US6387033B1 (en) * 2000-11-22 2002-05-14 Council Of Scientific And Industrial Research Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols
CA2446605A1 (en) * 2001-05-10 2002-11-21 Aventis Pharma Deutschland Gmbh Novel processes for the preparation of adenosine compounds and intermediates thereto
EP1574508A1 (de) * 2004-01-30 2005-09-14 Lonza AG Verfahren zur Herstellung von Acetalen und Ketalen von 3-Amino-5-(hydroxymethyl)-cyclopentan-1,2-diolen, sowie deren Derivaten und Salzen
KR101088669B1 (ko) * 2006-10-11 2011-12-01 닛뽕소다 가부시키가이샤 아자비시클로알칸올 유도체의 제조 방법
CN102311440B (zh) * 2010-07-02 2015-01-07 无锡药明康德生物技术有限公司 1-甲氧羰基-3-苄基-8-叔丁氧羰基-3,8-二氮杂双环[3.2.1]辛烷及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK532575A (da) * 1974-12-13 1976-06-14 Merck & Co Inc Fremgangsmade til racematspaltning af organiske forbindelser
US4508911A (en) * 1982-06-21 1985-04-02 The Upjohn Company Amine intermediates for analgesic compounds
US5284769A (en) * 1989-10-16 1994-02-08 Chiros Ltd. Process for preparing a single enantiomer of a lactam using lactamase
AU641712B2 (en) * 1989-12-13 1993-09-30 Noristan Holdings Limited Polycyclic nitrile compounds and pharmaceutical compositions thereof
JP2891740B2 (ja) * 1990-03-30 1999-05-17 塩野義製薬株式会社 光学活性ノルボルナン系アミン誘導体の製造方法
ES2095960T3 (es) * 1990-09-25 1997-03-01 Rhone Poulenc Rorer Int Compuestos que tienen propiedades antihipertensivas y antiisquemicas.
US5700895A (en) * 1993-08-23 1997-12-23 Sumitomo Chemical Company, Limited Ethylene-α-olefin copolymer and molded article thereof
FR2734822B1 (fr) * 1995-05-30 1997-07-04 Rhone Poulenc Rorer Sa Nouveaux derives du 2-azabicyclo(2.2.1)heptane, leur preparation et leur application
US5670649A (en) * 1995-05-30 1997-09-23 Rhone-Poulenc Rorer S.A. Derivatives of 2-azabicyclo 2.2.1!heptane, their preparation and their application
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds
US5856497A (en) * 1995-12-11 1999-01-05 Boehringer Ingelheim Pharmaceuticals, Inc. Asymmetric synthesis of α-cycloalkylalkyl substituted methanamines

Also Published As

Publication number Publication date
WO1998016510A1 (en) 1998-04-23
BG64733B1 (bg) 2006-01-31
BG64701B1 (bg) 2005-12-30
AP942A (en) 2001-02-16
US5684159A (en) 1997-11-04
IL129231A0 (en) 2000-02-17
CZ291387B6 (cs) 2003-02-12
ZA979268B (en) 1998-07-27
EP0934268A1 (en) 1999-08-11
NO991800L (no) 1999-06-15
US5831096A (en) 1998-11-03
US5808093A (en) 1998-09-15
CN1233239A (zh) 1999-10-27
NO20051757D0 (no) 2005-04-08
EA002438B1 (ru) 2002-04-25
EA199900382A1 (ru) 1999-10-28
CA2268652A1 (en) 1998-04-23
CN1094927C (zh) 2002-11-27
NO991800D0 (no) 1999-04-15
HUP9903583A2 (hu) 2000-04-28
CN1385422A (zh) 2002-12-18
AU721965B2 (en) 2000-07-20
PL332827A1 (en) 1999-10-11
NO20051757L (no) 1999-06-15
SK43799A3 (en) 2000-04-10
BG103296A (en) 2000-11-30
AP9901486A0 (en) 1999-03-31
EA200100661A1 (ru) 2001-12-24
BR9711910A (pt) 1999-08-24
HK1022475A1 (en) 2000-08-11
IL129231A (en) 2003-07-06
US5886192A (en) 1999-03-23
JP2001502329A (ja) 2001-02-20
HUP9903583A3 (en) 2000-10-30
KR20000049195A (ko) 2000-07-25
EA200100660A1 (ru) 2001-12-24
CZ131299A3 (cs) 2000-06-14
UA52702C2 (uk) 2003-01-15
EP0934268A4 (en) 2001-04-18
NO320332B1 (no) 2005-11-21
AU4816097A (en) 1998-05-11

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