IL129231A - Process for preparing 2-azadihydroxybicyclo [2.2.1] heptane compounds and the l-tartaric acid salt of the compounds - Google Patents

Process for preparing 2-azadihydroxybicyclo [2.2.1] heptane compounds and the l-tartaric acid salt of the compounds

Info

Publication number
IL129231A
IL129231A IL12923197A IL12923197A IL129231A IL 129231 A IL129231 A IL 129231A IL 12923197 A IL12923197 A IL 12923197A IL 12923197 A IL12923197 A IL 12923197A IL 129231 A IL129231 A IL 129231A
Authority
IL
Israel
Prior art keywords
compounds
azadihydroxybicyclo
preparing
acid salt
tartaric acid
Prior art date
Application number
IL12923197A
Other languages
English (en)
Other versions
IL129231A0 (en
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Priority to IL14535397A priority Critical patent/IL145353A0/xx
Priority to IL14535597A priority patent/IL145355A/xx
Priority to IL14535497A priority patent/IL145354A/xx
Publication of IL129231A0 publication Critical patent/IL129231A0/xx
Publication of IL129231A publication Critical patent/IL129231A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL12923197A 1996-10-16 1997-10-15 Process for preparing 2-azadihydroxybicyclo [2.2.1] heptane compounds and the l-tartaric acid salt of the compounds IL129231A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL14535397A IL145353A0 (en) 1996-10-16 1997-10-15 Process for preparing 2-azadihydroxybicyclo [2.2.1] heptane compounds and the l-tartaric acid salt of the compound
IL14535597A IL145355A (en) 1996-10-16 1997-10-15 L-tartaric acid salts of 2-azadihydroxybicyclo [2.2.1] heptane compounds
IL14535497A IL145354A (en) 1996-10-16 1997-10-15 Method for the preparation of 2-azadihydroxybicyclo [2.2.1] heptane compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/732,024 US5684159A (en) 1995-05-30 1996-10-16 L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds
PCT/US1997/018365 WO1998016510A1 (en) 1996-10-16 1997-10-15 Process for preparing 2-azadihydroxybicyclo[2.2.1]heptane compounds and the l-tartaric acid salt of the compound

Publications (2)

Publication Number Publication Date
IL129231A0 IL129231A0 (en) 2000-02-17
IL129231A true IL129231A (en) 2003-07-06

Family

ID=24941881

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12923197A IL129231A (en) 1996-10-16 1997-10-15 Process for preparing 2-azadihydroxybicyclo [2.2.1] heptane compounds and the l-tartaric acid salt of the compounds

Country Status (22)

Country Link
US (4) US5684159A (xx)
EP (1) EP0934268A4 (xx)
JP (1) JP2001502329A (xx)
KR (1) KR20000049195A (xx)
CN (2) CN1094927C (xx)
AP (1) AP942A (xx)
AU (1) AU721965B2 (xx)
BG (2) BG64733B1 (xx)
BR (1) BR9711910A (xx)
CA (1) CA2268652A1 (xx)
CZ (1) CZ291387B6 (xx)
EA (3) EA200100661A1 (xx)
HK (1) HK1022475A1 (xx)
HU (1) HUP9903583A3 (xx)
IL (1) IL129231A (xx)
NO (2) NO320332B1 (xx)
OA (1) OA11112A (xx)
PL (1) PL332827A1 (xx)
SK (1) SK43799A3 (xx)
UA (1) UA52702C2 (xx)
WO (1) WO1998016510A1 (xx)
ZA (1) ZA979268B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds
EP0926136B1 (en) * 1997-12-25 2004-05-12 Kuraray Co., Ltd. Process for producing and method of crystallizing 2-azabicyclo(2.2.1)hept-5-en-3-one
TW396337B (en) * 1998-02-13 2000-07-01 Mediatek Inc The automatic regulating device of cdrom optimum focusing spot and the method thereof
US5986100A (en) * 1998-04-02 1999-11-16 Crooks; Peter Anthony Pharmaceutical compositions and methods for use
US5952339A (en) * 1998-04-02 1999-09-14 Bencherif; Merouane Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release
US6057446A (en) 1998-04-02 2000-05-02 Crooks; Peter Anthony Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds
EP1140933B1 (en) 1998-12-31 2004-09-08 Aventis Pharmaceuticals Inc. Process for preparing n6-substituted deaza-adenosine derivatives
US6387033B1 (en) 2000-11-22 2002-05-14 Council Of Scientific And Industrial Research Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols
MXPA03009946A (es) * 2001-05-10 2005-03-07 Aventis Pharma Gmbh Nuevos procedimientos para la preparacion de compuestos de adenosina e intermedios para los mismos.
EP1574508A1 (de) * 2004-01-30 2005-09-14 Lonza AG Verfahren zur Herstellung von Acetalen und Ketalen von 3-Amino-5-(hydroxymethyl)-cyclopentan-1,2-diolen, sowie deren Derivaten und Salzen
JP5118053B2 (ja) * 2006-10-11 2013-01-16 日本曹達株式会社 アザビシクロアルカノール誘導体の製造方法
CN102311440B (zh) * 2010-07-02 2015-01-07 无锡药明康德生物技术有限公司 1-甲氧羰基-3-苄基-8-叔丁氧羰基-3,8-二氮杂双环[3.2.1]辛烷及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK532575A (da) * 1974-12-13 1976-06-14 Merck & Co Inc Fremgangsmade til racematspaltning af organiske forbindelser
US4508911A (en) * 1982-06-21 1985-04-02 The Upjohn Company Amine intermediates for analgesic compounds
US5284769A (en) * 1989-10-16 1994-02-08 Chiros Ltd. Process for preparing a single enantiomer of a lactam using lactamase
EP0433036A3 (en) * 1989-12-13 1992-01-22 Noristan Holdings Limited Polycyclic nitrile compounds and pharmaceutical compositions thereof
JP2891740B2 (ja) * 1990-03-30 1999-05-17 塩野義製薬株式会社 光学活性ノルボルナン系アミン誘導体の製造方法
ATE147074T1 (de) * 1990-09-25 1997-01-15 Rhone Poulenc Rorer Int Verbindungen welche antihypertensive und antiischemische eigenschaften besitzen
US5700895A (en) * 1993-08-23 1997-12-23 Sumitomo Chemical Company, Limited Ethylene-α-olefin copolymer and molded article thereof
US5670649A (en) * 1995-05-30 1997-09-23 Rhone-Poulenc Rorer S.A. Derivatives of 2-azabicyclo 2.2.1!heptane, their preparation and their application
US5684159A (en) * 1995-05-30 1997-11-04 Rhone-Poulenc Rorer S.A. L-tartaric acid salt of a (1R) diastereomer of a 2-azadihydroxybicyclo 2.2.1!heptane compound and the preparation of 2-azabicyclo 2.2.1!heptane compounds
FR2734822B1 (fr) * 1995-05-30 1997-07-04 Rhone Poulenc Rorer Sa Nouveaux derives du 2-azabicyclo(2.2.1)heptane, leur preparation et leur application
US5856497A (en) * 1995-12-11 1999-01-05 Boehringer Ingelheim Pharmaceuticals, Inc. Asymmetric synthesis of α-cycloalkylalkyl substituted methanamines

Also Published As

Publication number Publication date
WO1998016510A1 (en) 1998-04-23
IL129231A0 (en) 2000-02-17
US5808093A (en) 1998-09-15
CZ291387B6 (cs) 2003-02-12
EP0934268A4 (en) 2001-04-18
ZA979268B (en) 1998-07-27
NO991800D0 (no) 1999-04-15
PL332827A1 (en) 1999-10-11
AU4816097A (en) 1998-05-11
NO991800L (no) 1999-06-15
UA52702C2 (uk) 2003-01-15
EA200100660A1 (ru) 2001-12-24
HUP9903583A2 (hu) 2000-04-28
CA2268652A1 (en) 1998-04-23
HUP9903583A3 (en) 2000-10-30
EP0934268A1 (en) 1999-08-11
US5886192A (en) 1999-03-23
AP942A (en) 2001-02-16
NO20051757D0 (no) 2005-04-08
AU721965B2 (en) 2000-07-20
CN1094927C (zh) 2002-11-27
EA200100661A1 (ru) 2001-12-24
HK1022475A1 (en) 2000-08-11
JP2001502329A (ja) 2001-02-20
CN1385422A (zh) 2002-12-18
BG103296A (en) 2000-11-30
SK43799A3 (en) 2000-04-10
BR9711910A (pt) 1999-08-24
US5831096A (en) 1998-11-03
OA11112A (en) 2003-04-04
KR20000049195A (ko) 2000-07-25
AP9901486A0 (en) 1999-03-31
NO20051757L (no) 1999-06-15
CN1233239A (zh) 1999-10-27
US5684159A (en) 1997-11-04
CZ131299A3 (cs) 2000-06-14
EA002438B1 (ru) 2002-04-25
BG64701B1 (bg) 2005-12-30
NO320332B1 (no) 2005-11-21
EA199900382A1 (ru) 1999-10-28
BG64733B1 (bg) 2006-01-31

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Legal Events

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HK Corrigendum

Free format text: JOURNAL 4/03 P. 1292 PATENT APPLICATION NO. 129231 DELETE THE APPLICATION. THE APPLICATION WAS PUBLISHED BY MISTAKE. THE APPLICATION HAS NOT YET BEEN ACCEPTED AND IS NOT OPEN TO THE PUBLIC