OA10814A - Mixture of recombinant vaccinia vectors as polyenvvaccines for hiv - Google Patents

Mixture of recombinant vaccinia vectors as polyenvvaccines for hiv Download PDF

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Publication number
OA10814A
OA10814A OA9800118A OA9800118A OA10814A OA 10814 A OA10814 A OA 10814A OA 9800118 A OA9800118 A OA 9800118A OA 9800118 A OA9800118 A OA 9800118A OA 10814 A OA10814 A OA 10814A
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OAPI
Prior art keywords
hiv
virus
vaccine
recombinant
env
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OA9800118A
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English (en)
Inventor
Julia Hurwitz
Christopher Coleclough
Randall Owens
Karen Slobod
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St Jude Children's Res Hospita
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Publication of OA10814A publication Critical patent/OA10814A/en

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • C07K14/16HIV-1 ; HIV-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24171Demonstrated in vivo effect
    • CCHEMISTRY; METALLURGY
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
OA9800118A 1996-01-23 1998-07-22 Mixture of recombinant vaccinia vectors as polyenvvaccines for hiv OA10814A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/590,288 US5741492A (en) 1996-01-23 1996-01-23 Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses

Publications (1)

Publication Number Publication Date
OA10814A true OA10814A (en) 2003-01-28

Family

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Family Applications (1)

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OA9800118A OA10814A (en) 1996-01-23 1998-07-22 Mixture of recombinant vaccinia vectors as polyenvvaccines for hiv

Country Status (29)

Country Link
US (3) US5741492A (fr)
EP (2) EP0876498B1 (fr)
JP (2) JP2000504326A (fr)
KR (1) KR100571479B1 (fr)
CN (1) CN1229501C (fr)
AP (1) AP1200A (fr)
AT (1) ATE278790T1 (fr)
AU (1) AU709174B2 (fr)
BG (1) BG64711B1 (fr)
BR (1) BR9707611A (fr)
CA (1) CA2243570C (fr)
CZ (1) CZ296575B6 (fr)
DE (1) DE69731075T2 (fr)
DK (1) DK0876498T3 (fr)
EA (1) EA002390B1 (fr)
ES (1) ES2230596T3 (fr)
GE (1) GEP20032902B (fr)
HK (1) HK1016218A1 (fr)
HU (2) HU224344B1 (fr)
IL (2) IL125497A (fr)
NO (1) NO322261B1 (fr)
NZ (1) NZ331024A (fr)
OA (1) OA10814A (fr)
PL (1) PL188641B1 (fr)
PT (1) PT876498E (fr)
RO (1) RO120268B1 (fr)
TR (1) TR199801418T2 (fr)
UA (1) UA73712C2 (fr)
WO (1) WO1997027311A1 (fr)

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DE69731075D1 (de) 2004-11-11
WO1997027311A1 (fr) 1997-07-31
NO983377D0 (no) 1998-07-22
EP0876498B1 (fr) 2004-10-06
KR19990081931A (ko) 1999-11-15
DK0876498T3 (da) 2005-02-07
CN1229501C (zh) 2005-11-30
BG102712A (en) 1999-04-30
CZ296575B6 (cs) 2006-04-12
NO322261B1 (no) 2006-09-04
EP1378516A1 (fr) 2004-01-07
CZ229398A3 (cs) 1998-12-16
US5846546A (en) 1998-12-08
HK1016218A1 (en) 1999-10-29
AU1829997A (en) 1997-08-20
HUP9900389A3 (en) 2001-06-28
AP9801325A0 (en) 1998-09-30
HU224344B1 (hu) 2005-08-29
US5741492A (en) 1998-04-21
CA2243570C (fr) 2001-08-14
KR100571479B1 (ko) 2007-06-07
PL188641B1 (pl) 2005-03-31
DE69731075T2 (de) 2006-03-09
BG64711B1 (bg) 2005-12-30
ATE278790T1 (de) 2004-10-15
PT876498E (pt) 2005-02-28
AU709174B2 (en) 1999-08-26
HU0402182D0 (en) 2004-12-28
TR199801418T2 (xx) 1998-10-21
RO120268B1 (ro) 2005-11-30
JP2007259870A (ja) 2007-10-11
IL125497A0 (en) 1999-03-12
US6086891A (en) 2000-07-11
EA002390B1 (ru) 2002-04-25
GEP20032902B (en) 2003-02-25
PL328193A1 (en) 1999-01-18
BR9707611A (pt) 1999-07-27
HUP9900389A2 (hu) 1999-06-28
JP2000504326A (ja) 2000-04-11
IL125497A (en) 2007-07-04
EA199800638A1 (ru) 1999-02-25
NZ331024A (en) 2000-02-28
UA73712C2 (en) 2005-09-15
IL156919A0 (en) 2004-02-08
EP0876498A1 (fr) 1998-11-11
CA2243570A1 (fr) 1997-07-31
AP1200A (en) 2003-08-29
ES2230596T3 (es) 2005-05-01
CN1214083A (zh) 1999-04-14
NO983377L (no) 1998-09-23

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