OA08672A - Cephalosporin salts and injectable compositions. - Google Patents

Cephalosporin salts and injectable compositions.

Info

Publication number
OA08672A
OA08672A OA58918A OA58918A OA08672A OA 08672 A OA08672 A OA 08672A OA 58918 A OA58918 A OA 58918A OA 58918 A OA58918 A OA 58918A OA 08672 A OA08672 A OA 08672A
Authority
OA
OAPI
Prior art keywords
injectable compositions
cephalosporin salts
cephalosporin
salts
injectable
Prior art date
Application number
OA58918A
Other languages
English (en)
Inventor
A Kaplan Murray
Thomas W Hudyma
Robert A Lipper
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of OA08672A publication Critical patent/OA08672A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
OA58918A 1985-08-05 1986-08-05 Cephalosporin salts and injectable compositions. OA08672A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76223585A 1985-08-05 1985-08-05

Publications (1)

Publication Number Publication Date
OA08672A true OA08672A (en) 1989-03-31

Family

ID=25064475

Family Applications (1)

Application Number Title Priority Date Filing Date
OA58918A OA08672A (en) 1985-08-05 1986-08-05 Cephalosporin salts and injectable compositions.

Country Status (34)

Country Link
JP (1) JPH0615548B2 (pt)
KR (1) KR930003121B1 (pt)
AR (1) AR243894A1 (pt)
AT (1) AT390957B (pt)
AU (1) AU597262B2 (pt)
BE (1) BE905219A (pt)
CA (1) CA1284994C (pt)
CH (1) CH675581A5 (pt)
CS (2) CS276717B6 (pt)
CY (1) CY1614A (pt)
DD (2) DD254941A5 (pt)
DE (1) DE3626375A1 (pt)
DK (1) DK162053C (pt)
EG (1) EG18003A (pt)
ES (1) ES2002112A6 (pt)
FI (1) FI84484C (pt)
FR (1) FR2585705B1 (pt)
GB (1) GB2179936B (pt)
GR (1) GR862055B (pt)
HK (1) HK99691A (pt)
HU (1) HU196602B (pt)
IE (1) IE59222B1 (pt)
IL (1) IL79608A (pt)
IT (1) IT1197067B (pt)
LU (2) LU88574I2 (pt)
MY (1) MY102212A (pt)
NL (1) NL8601991A (pt)
OA (1) OA08672A (pt)
PT (1) PT83134B (pt)
SE (1) SE469633B (pt)
SG (1) SG79791G (pt)
SU (1) SU1516013A3 (pt)
YU (1) YU45793B (pt)
ZA (1) ZA865842B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) * 1984-12-27 1990-09-25 Banyu Pharmaceutical Company, Ltd. Crystalline cephalosporin compounds
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
US4910301A (en) * 1985-08-05 1990-03-20 Bristol-Myers Company Cefepime cephalosporin salts
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0321562B1 (en) * 1987-06-25 1993-11-24 Banyu Pharmaceutical Co., Ltd. Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
JPH02101081A (ja) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
JP4616844B2 (ja) 2003-12-23 2011-01-19 サンド・ゲーエムベーハー セファロスポリン合成に使用するための中間体の生成プロセス
WO2008056221A2 (en) * 2006-11-06 2008-05-15 Orchid Chemicals & Pharmaceuticals Limited Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
DE3419015A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von cephalosporinen
GB2165245B (en) * 1984-10-01 1988-05-25 Glaxo Group Ltd Chemical compounds
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
AU6069486A (en) 1987-02-12
JPS62103090A (ja) 1987-05-13
CA1284994C (en) 1991-06-18
KR930003121B1 (ko) 1993-04-19
SE8603308L (sv) 1987-02-06
ATA211086A (de) 1990-01-15
IT8621409A0 (it) 1986-08-04
SG79791G (en) 1991-11-15
MY102212A (en) 1992-05-15
ES2002112A6 (es) 1988-07-16
EG18003A (en) 1991-08-30
IE59222B1 (en) 1994-01-26
DD254941A5 (de) 1988-03-16
DE3626375A1 (de) 1987-02-12
DK162053C (da) 1992-02-10
CS276849B6 (en) 1992-08-12
PT83134B (pt) 1989-07-31
NL8601991A (nl) 1987-03-02
IL79608A (en) 1991-07-18
DD268395A5 (de) 1989-05-31
LU86540A1 (fr) 1987-03-06
AT390957B (de) 1990-07-25
IT1197067B (it) 1988-11-25
PT83134A (en) 1986-09-01
FI863155A0 (fi) 1986-08-01
FI84484B (fi) 1991-08-30
JPH0615548B2 (ja) 1994-03-02
KR880002530A (ko) 1988-05-09
AR243894A1 (es) 1993-09-30
CY1614A (en) 1992-07-10
DK162053B (da) 1991-09-09
FR2585705B1 (fr) 1989-01-13
IL79608A0 (en) 1986-11-30
FR2585705A1 (fr) 1987-02-06
SE8603308D0 (sv) 1986-08-04
GB8618989D0 (en) 1986-09-17
AU597262B2 (en) 1990-05-31
DK371886A (da) 1987-02-06
ZA865842B (en) 1987-04-29
IT8621409A1 (it) 1988-02-04
BE905219A (fr) 1987-02-04
IE862078L (en) 1987-02-05
YU45793B (sh) 1992-07-20
HU196602B (en) 1988-12-28
DK371886D0 (da) 1986-08-04
GR862055B (en) 1986-12-24
GB2179936B (en) 1989-04-26
FI863155A (fi) 1987-02-06
GB2179936A (en) 1987-03-18
LU88574I2 (fr) 1995-03-01
SE469633B (sv) 1993-08-09
FI84484C (fi) 1991-12-10
HUT41802A (en) 1987-05-28
HK99691A (en) 1991-12-13
SU1516013A3 (ru) 1989-10-15
CS276717B6 (en) 1992-08-12
CH675581A5 (pt) 1990-10-15
YU137186A (en) 1987-12-31

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