NZ599128A - Combination therapy treatment for viral infections - Google Patents
Combination therapy treatment for viral infectionsInfo
- Publication number
- NZ599128A NZ599128A NZ599128A NZ59912810A NZ599128A NZ 599128 A NZ599128 A NZ 599128A NZ 599128 A NZ599128 A NZ 599128A NZ 59912810 A NZ59912810 A NZ 59912810A NZ 599128 A NZ599128 A NZ 599128A
- Authority
- NZ
- New Zealand
- Prior art keywords
- receptor agonist
- antiviral agent
- combination therapy
- viral infections
- therapy treatment
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title 1
- 238000002648 combination therapy Methods 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
- 101150109738 Ptger4 gene Proteins 0.000 abstract 4
- 239000003443 antiviral agent Substances 0.000 abstract 4
- 239000000018 receptor agonist Substances 0.000 abstract 4
- 229940044601 receptor agonist Drugs 0.000 abstract 4
- OJIGXQJDLFUVFM-MBLRWRSDSA-N (5e)-5-[(3ar,4r,5r,6as)-5-hydroxy-4-[(e,3s)-3-hydroxy-4-methyloct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]-5-cyanopentanoic acid Chemical compound O1\C(=C(/CCCC(O)=O)C#N)C[C@@H]2[C@@H](/C=C/[C@@H](O)C(C)CCCC)[C@H](O)C[C@@H]21 OJIGXQJDLFUVFM-MBLRWRSDSA-N 0.000 abstract 1
- CTPOHARTNNSRSR-APJZLKAGSA-N beraprost Chemical compound O([C@H]1C[C@@H](O)[C@@H]([C@@H]21)/C=C/[C@@H](O)C(C)CC#CC)C1=C2C=CC=C1CCCC(O)=O CTPOHARTNNSRSR-APJZLKAGSA-N 0.000 abstract 1
- 229960002890 beraprost Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- UKTIJASCFRNWCB-RMIBSVFLSA-N laninamivir octanoate hydrate Chemical compound CCCCCCCC(=O)OC[C@@H](O)[C@@H](OC)[C@@H]1OC(C(O)=O)=C[C@H](N=C(N)N)[C@H]1NC(C)=O UKTIJASCFRNWCB-RMIBSVFLSA-N 0.000 abstract 1
- 229950004935 nileprost Drugs 0.000 abstract 1
- 229960003752 oseltamivir Drugs 0.000 abstract 1
- VSZGPKBBMSAYNT-RRFJBIMHSA-N oseltamivir Chemical compound CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 VSZGPKBBMSAYNT-RRFJBIMHSA-N 0.000 abstract 1
- XRQDFNLINLXZLB-CKIKVBCHSA-N peramivir Chemical compound CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@@H](C(O)=O)C[C@H]1NC(N)=N XRQDFNLINLXZLB-CKIKVBCHSA-N 0.000 abstract 1
- 229960001084 peramivir Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
- 229960001028 zanamivir Drugs 0.000 abstract 1
- ARAIBEBZBOPLMB-UFGQHTETSA-N zanamivir Chemical compound CC(=O)N[C@@H]1[C@@H](N=C(N)N)C=C(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ARAIBEBZBOPLMB-UFGQHTETSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25156109P | 2009-10-14 | 2009-10-14 | |
| PCT/US2010/052506 WO2011047048A1 (en) | 2009-10-14 | 2010-10-13 | Combination therapy treatment for viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ599128A true NZ599128A (en) | 2014-02-28 |
Family
ID=43063744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ599128A NZ599128A (en) | 2009-10-14 | 2010-10-13 | Combination therapy treatment for viral infections |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20120190637A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2488168A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2013508282A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20120093955A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102655859A (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012008959A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2777384A1 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ599128A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011047048A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2094273B1 (en) | 2006-11-16 | 2013-03-06 | Gemmus Pharma Inc. | EP2 and EP4 agonists as agents for the treatment of influenza A viral infection |
| WO2014151085A1 (en) * | 2013-03-15 | 2014-09-25 | Gemmus Pharma Inc. | Beraprost isomer as agent for the treatment of viral infection |
| WO2015109112A1 (en) * | 2014-01-16 | 2015-07-23 | Gemmus Pharma Inc. | Combination treatment of antibiotic and gpcr agonist for viral/bacterial co-infections |
| CA3059362A1 (en) * | 2017-04-12 | 2018-10-18 | Vertex Pharmaceuticals Incorporated | Combination therapies for treating influenza virus infection |
| CN111265528A (zh) * | 2020-01-21 | 2020-06-12 | 中国人民解放军军事科学院军事医学研究院 | 法匹拉韦在治疗冠状病毒感染方面的应用 |
| CA3167058A1 (en) | 2020-02-12 | 2021-08-19 | Cytoagents, Inc. | Compositions and methods for treating coronavirus infections |
| CN111184707B (zh) * | 2020-02-20 | 2021-04-27 | 中山大学 | 托芬那酸或其药学上可接受的盐在制备预防和/或治疗新型冠状病毒炎症药物中的应用 |
| MX2022013021A (es) * | 2020-04-30 | 2023-01-16 | Minoryx Therapeutics S L | Leriglitazona para tratar inflamacion pulmonar y enfermedad pulmonar intersticial. |
| US20230147364A1 (en) * | 2020-04-30 | 2023-05-11 | Kyoto University | Prophylactic or therapeutic agent for rna virus-related diseases |
| US20210386725A1 (en) * | 2020-06-11 | 2021-12-16 | Chang Gung University | Method for inhibiting coronavirus infection and replication |
| US20240009214A1 (en) | 2020-12-02 | 2024-01-11 | Cipla Limited | Method of Treating Viral Infection |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2845770A1 (de) | 1978-10-19 | 1980-04-30 | Schering Ag | Neue prostacyclin-derivate und verfahren zu ihrer herstellung |
| DE3048906A1 (de) | 1980-12-19 | 1982-07-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS58124778A (ja) | 1982-01-20 | 1983-07-25 | Toray Ind Inc | ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体 |
| DE3226550A1 (de) | 1982-07-13 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3306123A1 (de) | 1983-02-18 | 1984-09-06 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3740838A1 (de) | 1987-11-27 | 1989-06-08 | Schering Ag | Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel |
| NZ525164A (en) | 2000-11-27 | 2005-04-29 | Pfizer Prod Inc | EP4 receptor selective agonists in the treatment of osteoporosis |
| GB0031295D0 (en) | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Naphthalene derivatives |
| GB0031302D0 (en) | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Napthalene derivatives |
| US20030027853A1 (en) | 2001-06-14 | 2003-02-06 | Allergan Sales, Inc. | 3, 7or3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure |
| TWI313608B (en) | 2001-07-23 | 2009-08-21 | Ono Pharmaceutical Co | Lower bone mass treating agent containing er4 agonist as active ingredient |
| EP1461026A2 (en) | 2001-12-03 | 2004-09-29 | Merck & Co., Inc. | Method for treating ocular hypertension |
| EP1453503A4 (en) | 2001-12-03 | 2005-03-30 | Merck & Co Inc | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS |
| IL164263A0 (en) | 2002-04-12 | 2005-12-18 | Pfizer | Use of ep4 receptor ligands on the treatment of il-6 involved diseases |
| CA2488001C (en) | 2002-06-06 | 2011-03-22 | Merck Frosst Canada & Co. | 1,5-distributed pyrrolid-2-one derivatives for use as ep4 receptor agonists in the treatment of eye diseases such as glaucoma |
| CA2487977A1 (en) | 2002-06-06 | 2003-12-18 | Merck Frosst Canada & Co./Merck Frosst Canada & Cie | 1,5-disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases |
| WO2004019938A1 (en) | 2002-08-28 | 2004-03-11 | Merck Frosst Canada & Co. | Oxazolidin-2-one and thiazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of glaucoma |
| WO2004037786A2 (en) | 2002-10-25 | 2004-05-06 | Merck Frosst Canada & Co. | 2-pyrrolidones as ep4 receptor agonists |
| US7053085B2 (en) | 2003-03-26 | 2006-05-30 | Merck & Co. Inc. | EP4 receptor agonist, compositions and methods thereof |
| US7256211B1 (en) | 2003-01-21 | 2007-08-14 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivatives and medical use thereof |
| MXPA05008431A (es) | 2003-02-11 | 2005-10-19 | Allergan Inc | Derivados de acido 10,10-dialquil prostanoico como agentes para reducir la presion intraocular. |
| GB0306907D0 (en) | 2003-03-26 | 2003-04-30 | Angiogene Pharm Ltd | Boireductively-activated prodrugs |
| US6747037B1 (en) | 2003-06-06 | 2004-06-08 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| US7326716B2 (en) | 2003-06-06 | 2008-02-05 | Allergan, Inc. | Treatment of inflammatory bowel disease |
| US7015243B2 (en) | 2003-08-28 | 2006-03-21 | Allergan, Inc. | Cyclohexyl prostaglandin analogs as EP4-receptor agonists |
| WO2005027931A1 (en) | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and an ep2 or ep4 selective agonist |
| MXPA06006810A (es) | 2003-12-17 | 2006-08-23 | Pfizer Prod Inc | Tratamiento de afecciones que se presentan con un nivel bajo de masa osea por terapia de combinacion continua con agonistas selectivos del receptor de prostaglandina ep4 y un estrogeno. |
| US7169807B2 (en) | 2004-04-09 | 2007-01-30 | Allergan, Inc. | 10-Hydroxy-11-dihydroprostaglandin analogs as selective EP4 agonists |
| WO2005116010A1 (en) | 2004-05-26 | 2005-12-08 | Merck Frosst Canada Ltd. | Ep4 receptor agonist, compositions and methods thereof |
| WO2006016695A1 (ja) | 2004-08-10 | 2006-02-16 | Ono Pharmaceutical Co., Ltd. | Ｅｐ４アゴニストを含有してなる高カリウム血症の予防および／または治療剤 |
| EP1805139A2 (en) | 2004-10-26 | 2007-07-11 | Allergan, Inc. | Therapeutic and delivery methods of prostaglandin ep4 agonists |
| WO2006052630A1 (en) | 2004-11-04 | 2006-05-18 | Allergan, Inc. | Therapeutic substituted piperidone compounds |
| US7101906B2 (en) | 2004-11-16 | 2006-09-05 | Allergan, Inc. | 2,3,4-substituted cyclopentanones as therapeutic agents |
| US7183324B2 (en) | 2004-11-23 | 2007-02-27 | Allergan, Inc. | 2,3,4-substituted cyclopentanones as therapeutic agents |
| CA2596003C (en) | 2005-01-27 | 2012-12-18 | Asahi Kasei Pharma Corporation | Six-membered heterocyclic compound and use thereof |
| WO2006137472A1 (ja) | 2005-06-24 | 2006-12-28 | Taisho Pharmaceutical Co., Ltd. | プロスタグランジン誘導体 |
| JP2009502982A (ja) | 2005-08-03 | 2009-01-29 | メルク フロスト カナダ リミテツド | Ｅｐ４受容体アゴニスト、この組成物および方法 |
| AU2006275270A1 (en) | 2005-08-03 | 2007-02-08 | Merck Frosst Canada Ltd | EP4 receptor agonist, compositions and methods thereof |
| US7893107B2 (en) | 2005-11-30 | 2011-02-22 | Allergan, Inc. | Therapeutic methods using prostaglandin EP4 agonist components |
| GB0602900D0 (en) | 2006-02-13 | 2006-03-22 | Glaxo Group Ltd | Novel Compounds |
| WO2007139150A1 (ja) * | 2006-05-30 | 2007-12-06 | The University Of Tokushima | ＴＮＦα阻害物質を含有してなる抗インフルエンザウイルス剤 |
| EP2035376B1 (en) | 2006-06-12 | 2014-08-27 | Merck Canada Inc. | Indoline amide derivatives as ep4 receptor ligands |
| GB0615111D0 (en) | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
| GB0615105D0 (en) | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
| JP5259592B2 (ja) | 2006-08-11 | 2013-08-07 | メルク カナダ インコーポレイテッド | Ｅｐ４受容体リガンドとしてのチオフェンカルボキサミド誘導体 |
| GB0620619D0 (en) | 2006-10-17 | 2006-11-29 | Glaxo Group Ltd | Novel compounds |
| EP2094273B1 (en) | 2006-11-16 | 2013-03-06 | Gemmus Pharma Inc. | EP2 and EP4 agonists as agents for the treatment of influenza A viral infection |
| GB0623203D0 (en) | 2006-11-21 | 2007-01-03 | Glaxo Group Ltd | Novel compounds |
| EA015931B1 (ru) | 2006-12-15 | 2011-12-30 | Глэксо Груп Лимитед | Бензамидные производные как агонисты ер-рецепторов |
| EP1975163A1 (en) * | 2007-03-28 | 2008-10-01 | Bayer Schering Pharma Aktiengesellschaft | Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of influenza a viral infection |
| US7776896B2 (en) | 2007-03-28 | 2010-08-17 | Bayer Schering Pharma Aktiengesellschaft | 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection |
| CA2684922A1 (en) | 2007-05-08 | 2008-11-13 | National University Corporation, Hamamatsu University School Of Medicine | Cytotoxic t cell activator comprising ep4 agonist |
-
2010
- 2010-10-13 JP JP2012534324A patent/JP2013508282A/ja active Pending
- 2010-10-13 US US13/129,108 patent/US20120190637A1/en not_active Abandoned
- 2010-10-13 BR BR112012008959A patent/BR112012008959A2/pt not_active IP Right Cessation
- 2010-10-13 EP EP10768160A patent/EP2488168A1/en not_active Withdrawn
- 2010-10-13 KR KR1020127012323A patent/KR20120093955A/ko not_active Ceased
- 2010-10-13 CN CN2010800567360A patent/CN102655859A/zh active Pending
- 2010-10-13 NZ NZ599128A patent/NZ599128A/en not_active IP Right Cessation
- 2010-10-13 CA CA2777384A patent/CA2777384A1/en not_active Abandoned
- 2010-10-13 WO PCT/US2010/052506 patent/WO2011047048A1/en not_active Ceased
-
2014
- 2014-12-10 US US14/566,354 patent/US20150196578A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112012008959A2 (pt) | 2019-09-24 |
| JP2013508282A (ja) | 2013-03-07 |
| AU2010306914A1 (en) | 2012-04-19 |
| KR20120093955A (ko) | 2012-08-23 |
| CN102655859A (zh) | 2012-09-05 |
| US20120190637A1 (en) | 2012-07-26 |
| EP2488168A1 (en) | 2012-08-22 |
| US20150196578A1 (en) | 2015-07-16 |
| WO2011047048A1 (en) | 2011-04-21 |
| CA2777384A1 (en) | 2011-04-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ599128A (en) | Combination therapy treatment for viral infections | |
| EA201270221A1 (ru) | Лечение болезни крона с применением лаквинимода | |
| EA201100305A1 (ru) | Лечение респираторных заболеваний | |
| PH12018500023A1 (en) | Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof | |
| MX2010009623A (es) | Derivados de 1-bencil-3-hidroximetilindazol novedosos y su uso en el tratamiento de enfermedades basadas en la expresion de mcp-1, cx3cr1 y p40. | |
| JP2010222367A5 (cg-RX-API-DMAC7.html) | ||
| PE20120713A1 (es) | Composiciones sublinguales de dexmedetomidina y metodos para su uso | |
| NZ599847A (en) | Pharmaceutical composition comprising a glp-1 agonist and methionine | |
| NZ602510A (en) | Treatment of lupus nephritis using laquinimod | |
| MX2010009625A (es) | Derivados de 1-bencil-3-hidroximetilindazol y uso de los mismos en el tratamiento de enfermedades basadas en la expresion de mcp-1, cx3cr1 y p40. | |
| WO2009123776A3 (en) | Antiviral drugs for treatment of arenavirus infection | |
| MX351059B (es) | Composicion farmaceutica oral en forma de microesferas y proceso de elaboracion. | |
| RU2019143573A (ru) | Комбинированная терапия нейропсихиатрических расстройств, восприимчивых к антагонисту nmdar | |
| MX2010009624A (es) | Derivados de 1-bencil-3-hidroximetilindazol y uso de los mismos en el tratamiento de enfermedades basadas en la expresion de mcp-1 y cx3cr1. | |
| MX2007011174A (es) | Metodos y formulaciones de metformina para tratar constipacion cronica. | |
| RU2015109566A (ru) | НОВЫЕ ЭКСТРАКТЫ ИЗ CYNARA SCOLYMUS, COFFEA spp. И OLEA EUROPAEA ДЛЯ ЛЕЧЕНИЯ МЕТАБОЛИЧЕСКОГО СИНДРОМА | |
| NZ591408A (en) | Paracetamol and Calcium carbonate composition | |
| HK1223825A1 (zh) | 包含阿曲生坦的稳定化药物剂型 | |
| MX2008011321A (es) | Composicion farmaceutica para el uso en el tratamiento de infecciones de transmision sexual. | |
| EA201300248A1 (ru) | Фармацевтическая композиция, обладающая противогипоксической, нейропротекторной и антиамнестической активностью и повышающая физическую работоспособность | |
| PH12014501601A1 (en) | Artemisinin-based combination therapy for treating viral mediated disease | |
| NZ611706A (en) | Pharmaceutical compositions of tenecteplase | |
| AR061728A1 (es) | Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1 | |
| WO2003051301A3 (en) | USE OF dsRNAs IN STRATEGIC THERAPEUTIC INTERVENTION OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY | |
| TW200724147A (en) | Cognitive abilities improving agent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 OCT 2015 BY COMPUTER PACKAGES INC Effective date: 20140918 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 OCT 2016 BY COMPUTER PACKAGES INC Effective date: 20150918 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 OCT 2017 BY COMPUTER PACKAGES INC Effective date: 20161001 |
|
| LAPS | Patent lapsed |