JP2013508282A - ウイルス感染のための併用療法処置 - Google Patents

ウイルス感染のための併用療法処置 Download PDF

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Publication number
JP2013508282A
JP2013508282A JP2012534324A JP2012534324A JP2013508282A JP 2013508282 A JP2013508282 A JP 2013508282A JP 2012534324 A JP2012534324 A JP 2012534324A JP 2012534324 A JP2012534324 A JP 2012534324A JP 2013508282 A JP2013508282 A JP 2013508282A
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antiviral agent
receptor agonist
hydroxy
administered
hydroxyl
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Japanese (ja)
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JP2013508282A5 (cg-RX-API-DMAC7.html
Inventor
ジェイ.ギルフォード ウィリアム
エイチ.フォールズ ダリル
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ジェンムス ファーマ インコーポレイティド
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Publication of JP2013508282A5 publication Critical patent/JP2013508282A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41661,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012534324A 2009-10-14 2010-10-13 ウイルス感染のための併用療法処置 Pending JP2013508282A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25156109P 2009-10-14 2009-10-14
US61/251,561 2009-10-14
PCT/US2010/052506 WO2011047048A1 (en) 2009-10-14 2010-10-13 Combination therapy treatment for viral infections

Publications (2)

Publication Number Publication Date
JP2013508282A true JP2013508282A (ja) 2013-03-07
JP2013508282A5 JP2013508282A5 (cg-RX-API-DMAC7.html) 2013-12-05

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JP2012534324A Pending JP2013508282A (ja) 2009-10-14 2010-10-13 ウイルス感染のための併用療法処置

Country Status (9)

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US (2) US20120190637A1 (cg-RX-API-DMAC7.html)
EP (1) EP2488168A1 (cg-RX-API-DMAC7.html)
JP (1) JP2013508282A (cg-RX-API-DMAC7.html)
KR (1) KR20120093955A (cg-RX-API-DMAC7.html)
CN (1) CN102655859A (cg-RX-API-DMAC7.html)
BR (1) BR112012008959A2 (cg-RX-API-DMAC7.html)
CA (1) CA2777384A1 (cg-RX-API-DMAC7.html)
NZ (1) NZ599128A (cg-RX-API-DMAC7.html)
WO (1) WO2011047048A1 (cg-RX-API-DMAC7.html)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020516634A (ja) * 2017-04-12 2020-06-11 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated インフルエンザウイルス感染の処置方法および併用療法
JP2021116296A (ja) * 2020-01-21 2021-08-10 アカデミー オブ ミリタリー メディカル サイエンシズ コロナウイルス感染の治療におけるファビピラビルの使用
JPWO2021221111A1 (cg-RX-API-DMAC7.html) * 2020-04-30 2021-11-04
JP2023525981A (ja) * 2020-04-30 2023-06-20 ミノリックス セラピューティクス エセ.エレ. 肺炎症および間質性肺疾患を処置するためのレリグリタゾン

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EP2094273B1 (en) 2006-11-16 2013-03-06 Gemmus Pharma Inc. EP2 and EP4 agonists as agents for the treatment of influenza A viral infection
WO2014151085A1 (en) * 2013-03-15 2014-09-25 Gemmus Pharma Inc. Beraprost isomer as agent for the treatment of viral infection
WO2015109112A1 (en) * 2014-01-16 2015-07-23 Gemmus Pharma Inc. Combination treatment of antibiotic and gpcr agonist for viral/bacterial co-infections
CA3167058A1 (en) 2020-02-12 2021-08-19 Cytoagents, Inc. Compositions and methods for treating coronavirus infections
CN111184707B (zh) * 2020-02-20 2021-04-27 中山大学 托芬那酸或其药学上可接受的盐在制备预防和/或治疗新型冠状病毒炎症药物中的应用
US20210386725A1 (en) * 2020-06-11 2021-12-16 Chang Gung University Method for inhibiting coronavirus infection and replication
US20240009214A1 (en) 2020-12-02 2024-01-11 Cipla Limited Method of Treating Viral Infection

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020516634A (ja) * 2017-04-12 2020-06-11 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated インフルエンザウイルス感染の処置方法および併用療法
JP2021116296A (ja) * 2020-01-21 2021-08-10 アカデミー オブ ミリタリー メディカル サイエンシズ コロナウイルス感染の治療におけるファビピラビルの使用
JP7716189B2 (ja) 2020-01-21 2025-07-31 アカデミー オブ ミリタリー メディカル サイエンシズ コロナウイルス感染の治療におけるファビピラビルの使用
JPWO2021221111A1 (cg-RX-API-DMAC7.html) * 2020-04-30 2021-11-04
WO2021221111A1 (ja) * 2020-04-30 2021-11-04 国立大学法人京都大学 Rnaウイルス関連疾患の予防又は治療剤
JP2023525981A (ja) * 2020-04-30 2023-06-20 ミノリックス セラピューティクス エセ.エレ. 肺炎症および間質性肺疾患を処置するためのレリグリタゾン
JP7715353B2 (ja) 2020-04-30 2025-07-30 国立大学法人京都大学 Rnaウイルス関連疾患の予防又は治療剤

Also Published As

Publication number Publication date
NZ599128A (en) 2014-02-28
BR112012008959A2 (pt) 2019-09-24
AU2010306914A1 (en) 2012-04-19
KR20120093955A (ko) 2012-08-23
CN102655859A (zh) 2012-09-05
US20120190637A1 (en) 2012-07-26
EP2488168A1 (en) 2012-08-22
US20150196578A1 (en) 2015-07-16
WO2011047048A1 (en) 2011-04-21
CA2777384A1 (en) 2011-04-21

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