NZ598166A - Methods, primers, probes and kits useful for the detection of braf mutations - Google Patents
Methods, primers, probes and kits useful for the detection of braf mutationsInfo
- Publication number
- NZ598166A NZ598166A NZ598166A NZ59816610A NZ598166A NZ 598166 A NZ598166 A NZ 598166A NZ 598166 A NZ598166 A NZ 598166A NZ 59816610 A NZ59816610 A NZ 59816610A NZ 598166 A NZ598166 A NZ 598166A
- Authority
- NZ
- New Zealand
- Prior art keywords
- braf
- sample
- dna sequence
- amplification reaction
- sequence
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000035772 mutation Effects 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 239000000523 sample Substances 0.000 title 1
- 101000984753 Homo sapiens Serine/threonine-protein kinase B-raf Proteins 0.000 abstract 10
- 102100027103 Serine/threonine-protein kinase B-raf Human genes 0.000 abstract 10
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 8
- 230000003321 amplification Effects 0.000 abstract 7
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 7
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 2
- 238000000137 annealing Methods 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23305409P | 2009-08-11 | 2009-08-11 | |
| US23707809P | 2009-08-26 | 2009-08-26 | |
| US30179010P | 2010-02-05 | 2010-02-05 | |
| PCT/US2010/044997 WO2011019704A2 (en) | 2009-08-11 | 2010-08-10 | Methods, primers, probes and kits useful for the detection of braf mutations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ598166A true NZ598166A (en) | 2014-03-28 |
Family
ID=43586772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ598166A NZ598166A (en) | 2009-08-11 | 2010-08-10 | Methods, primers, probes and kits useful for the detection of braf mutations |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20140248614A1 (enExample) |
| EP (1) | EP2464751B1 (enExample) |
| JP (1) | JP2013501523A (enExample) |
| KR (1) | KR20120099630A (enExample) |
| CN (1) | CN102575295B (enExample) |
| AR (1) | AR077844A1 (enExample) |
| AU (1) | AU2010282632A1 (enExample) |
| CA (1) | CA2770716A1 (enExample) |
| IL (1) | IL218021A0 (enExample) |
| NZ (1) | NZ598166A (enExample) |
| TW (1) | TW201111517A (enExample) |
| WO (1) | WO2011019704A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6153758B2 (ja) * | 2012-04-20 | 2017-06-28 | アークレイ株式会社 | 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット |
| US10077474B2 (en) | 2012-05-29 | 2018-09-18 | Abbott Molecular, Inc. | Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits |
| CN102816851A (zh) * | 2012-08-29 | 2012-12-12 | 苏州旷远生物分子技术有限公司 | 用于检测braf基因v600e突变的引物、探针、试剂盒及方法 |
| CN102876784B (zh) * | 2012-09-13 | 2014-11-19 | 周宏灏 | 焦磷酸测序法检测B-raf基因多态性的试剂盒及方法 |
| EP2711432A1 (en) * | 2012-09-21 | 2014-03-26 | Genomica S.A.U. | Method for detection of BRAF and PI3K mutations |
| EP3473250B1 (en) | 2012-12-27 | 2022-08-17 | Quest Diagnostics Investments Incorporated | Ddr2 mutations as targetable features of melanoma or basal cell carcinoma |
| CN103103269B (zh) * | 2013-01-18 | 2015-07-15 | 陕西佰美基因股份有限公司 | 一种基于探针熔解技术准确检测braf基因突变的方法 |
| JP2016512041A (ja) * | 2013-03-15 | 2016-04-25 | アボツト・モレキユラー・インコーポレイテツド | 多重対立遺伝子の検出 |
| KR101378920B1 (ko) * | 2013-04-18 | 2014-03-27 | 주식회사 현일바이오 | Ｂｒａｆ 돌연변이의 선택적 검출 방법 및 이를 이용한 키트 |
| US20160108479A1 (en) * | 2013-08-14 | 2016-04-21 | Qiagen Mansfield, Inc. | Compositions and methods for multiplex analysis of nras and braf nucleic acids |
| CN104017887A (zh) * | 2014-06-18 | 2014-09-03 | 广州好芝生物科技有限公司 | 人类braf基因突变检测引物对和探针及其试剂盒 |
| CA2954689A1 (en) * | 2014-07-11 | 2016-01-14 | Expression Pathology, Inc. | Srm/mrm assay for the serine/threonine-protein kinase b-raf (braf) |
| CN105400900A (zh) * | 2015-12-29 | 2016-03-16 | 杭州迪安生物技术有限公司 | 焦磷酸测序技术检测braf基因v600e微量突变试剂盒及其应用 |
| CN105861691A (zh) * | 2016-05-06 | 2016-08-17 | 北京晋祺生物科技有限公司 | 一种braf基因突变检测的引物组合物、试剂盒及方法 |
| US12364776B2 (en) | 2017-06-29 | 2025-07-22 | Korea Advanced Institute Of Science And Technology | Ganglioglioma-induced animal model and a method for diagnosing and treating ganglioglioma and related diseases |
| KR20190038464A (ko) * | 2017-09-29 | 2019-04-08 | (재)록원바이오융합연구재단 | Ras/braf 돌연변이 검출용 조성물 및 이를 포함하는 키트 |
| CN109161594A (zh) * | 2018-08-17 | 2019-01-08 | 中山大学达安基因股份有限公司 | 一种检测braf基因突变的方法及其试剂盒 |
| WO2022119423A1 (ko) * | 2020-12-04 | 2022-06-09 | 주식회사 제노픽스 | 폐암 유전자 돌연변이 초고감도 선택적 증폭 방법 및 이를 위한 조성물 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004337120A (ja) * | 2003-05-19 | 2004-12-02 | Chang Gung Univ | 膀胱癌再発検査方法 |
| US7745125B2 (en) * | 2004-06-28 | 2010-06-29 | Roche Molecular Systems, Inc. | 2′-terminator related pyrophosphorolysis activated polymerization |
| CN101487051B (zh) * | 2009-02-24 | 2011-07-20 | 广州益善生物技术有限公司 | Braf基因突变的检测探针、液相芯片及其检测方法 |
-
2010
- 2010-08-10 NZ NZ598166A patent/NZ598166A/en not_active IP Right Cessation
- 2010-08-10 CN CN201080045765.7A patent/CN102575295B/zh not_active Expired - Fee Related
- 2010-08-10 JP JP2012524782A patent/JP2013501523A/ja active Pending
- 2010-08-10 KR KR1020127004699A patent/KR20120099630A/ko not_active Ceased
- 2010-08-10 CA CA2770716A patent/CA2770716A1/en not_active Abandoned
- 2010-08-10 WO PCT/US2010/044997 patent/WO2011019704A2/en not_active Ceased
- 2010-08-10 EP EP10808619.0A patent/EP2464751B1/en not_active Not-in-force
- 2010-08-10 AU AU2010282632A patent/AU2010282632A1/en not_active Abandoned
- 2010-08-11 TW TW099126740A patent/TW201111517A/zh unknown
- 2010-08-11 AR ARP100102935A patent/AR077844A1/es unknown
-
2012
- 2012-02-09 IL IL218021A patent/IL218021A0/en unknown
-
2014
- 2014-02-27 US US14/192,414 patent/US20140248614A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011019704A3 (en) | 2011-07-07 |
| CN102575295A (zh) | 2012-07-11 |
| EP2464751A4 (en) | 2013-07-03 |
| KR20120099630A (ko) | 2012-09-11 |
| AU2010282632A1 (en) | 2012-03-08 |
| IL218021A0 (en) | 2012-04-30 |
| AR077844A1 (es) | 2011-09-28 |
| TW201111517A (en) | 2011-04-01 |
| EP2464751A2 (en) | 2012-06-20 |
| EP2464751B1 (en) | 2017-05-24 |
| CN102575295B (zh) | 2016-02-17 |
| JP2013501523A (ja) | 2013-01-17 |
| WO2011019704A2 (en) | 2011-02-17 |
| US20140248614A1 (en) | 2014-09-04 |
| CA2770716A1 (en) | 2011-02-17 |
| HK1172931A1 (zh) | 2013-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 10 AUG 2017 BY SHELSTON IP Effective date: 20140703 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 AUG 2018 BY THOMSON REUTERS Effective date: 20170720 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 AUG 2019 BY THOMSON REUTERS Effective date: 20180721 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 10 AUG 2020 BY THOMSON REUTERS Effective date: 20190725 |
|
| LAPS | Patent lapsed |