HK1172931A1 - 可用於檢測 突變的方法、引物、探針和試劑盒 - Google Patents

可用於檢測 突變的方法、引物、探針和試劑盒

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Publication number
HK1172931A1
HK1172931A1 HK13100094.0A HK13100094A HK1172931A1 HK 1172931 A1 HK1172931 A1 HK 1172931A1 HK 13100094 A HK13100094 A HK 13100094A HK 1172931 A1 HK1172931 A1 HK 1172931A1
Authority
HK
Hong Kong
Prior art keywords
braf
primers
probes
detection
methods
Prior art date
Application number
HK13100094.0A
Other languages
English (en)
Inventor
Craig Stephens
Kathleen Danenberg
Original Assignee
應答遺傳公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 應答遺傳公司 filed Critical 應答遺傳公司
Publication of HK1172931A1 publication Critical patent/HK1172931A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
HK13100094.0A 2009-08-11 2013-01-04 可用於檢測 突變的方法、引物、探針和試劑盒 HK1172931A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23305409P 2009-08-11 2009-08-11
US23707809P 2009-08-26 2009-08-26
US30179010P 2010-02-05 2010-02-05
PCT/US2010/044997 WO2011019704A2 (en) 2009-08-11 2010-08-10 Methods, primers, probes and kits useful for the detection of braf mutations

Publications (1)

Publication Number Publication Date
HK1172931A1 true HK1172931A1 (zh) 2013-05-03

Family

ID=43586772

Family Applications (1)

Application Number Title Priority Date Filing Date
HK13100094.0A HK1172931A1 (zh) 2009-08-11 2013-01-04 可用於檢測 突變的方法、引物、探針和試劑盒

Country Status (13)

Country Link
US (1) US20140248614A1 (zh)
EP (1) EP2464751B1 (zh)
JP (1) JP2013501523A (zh)
KR (1) KR20120099630A (zh)
CN (1) CN102575295B (zh)
AR (1) AR077844A1 (zh)
AU (1) AU2010282632A1 (zh)
CA (1) CA2770716A1 (zh)
HK (1) HK1172931A1 (zh)
IL (1) IL218021A0 (zh)
NZ (1) NZ598166A (zh)
TW (1) TW201111517A (zh)
WO (1) WO2011019704A2 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6153758B2 (ja) * 2012-04-20 2017-06-28 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット
US10077474B2 (en) 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
CN102816851A (zh) * 2012-08-29 2012-12-12 苏州旷远生物分子技术有限公司 用于检测braf基因v600e突变的引物、探针、试剂盒及方法
CN102876784B (zh) * 2012-09-13 2014-11-19 周宏灏 焦磷酸测序法检测B-raf基因多态性的试剂盒及方法
EP2711432A1 (en) * 2012-09-21 2014-03-26 Genomica S.A.U. Method for detection of BRAF and PI3K mutations
CA3077539C (en) * 2012-12-27 2023-09-12 Quest Diagnostics Investments Incorporated Ddr2 mutations as targetable features of melanoma or basal cell carcinoma
CN103103269B (zh) * 2013-01-18 2015-07-15 陕西佰美基因股份有限公司 一种基于探针熔解技术准确检测braf基因突变的方法
JP2016512041A (ja) * 2013-03-15 2016-04-25 アボツト・モレキユラー・インコーポレイテツド 多重対立遺伝子の検出
KR101378920B1 (ko) * 2013-04-18 2014-03-27 주식회사 현일바이오 Ｂｒａｆ 돌연변이의 선택적 검출 방법 및 이를 이용한 키트
CN105705655A (zh) * 2013-08-14 2016-06-22 佳根曼斯菲尔德有限公司 用于对nras和braf核酸进行多重分析的组合物及方法
CN104017887A (zh) * 2014-06-18 2014-09-03 广州好芝生物科技有限公司 人类braf基因突变检测引物对和探针及其试剂盒
KR20190095523A (ko) * 2014-07-11 2019-08-14 익스프레션 패톨로지, 인크. 세린/트레오닌-단백질 키나제 수용체 B-raf(BRAF)에 대한 SRM/MRM 검정
CN105400900A (zh) * 2015-12-29 2016-03-16 杭州迪安生物技术有限公司 焦磷酸测序技术检测braf基因v600e微量突变试剂盒及其应用
CN105861691A (zh) * 2016-05-06 2016-08-17 北京晋祺生物科技有限公司 一种braf基因突变检测的引物组合物、试剂盒及方法
US20200360537A1 (en) * 2017-06-29 2020-11-19 Korea Advanced Institute Of Science And Technology A ganglioglioma-induced animal model and a method for diagnosing and treating ganglioglioma and related diseases
KR20190038464A (ko) * 2017-09-29 2019-04-08 (재)록원바이오융합연구재단 Ras/braf 돌연변이 검출용 조성물 및 이를 포함하는 키트
CN109161594A (zh) * 2018-08-17 2019-01-08 中山大学达安基因股份有限公司 一种检测braf基因突变的方法及其试剂盒
KR20220079492A (ko) * 2020-12-04 2022-06-13 주식회사 제노픽스 폐암 유전자 돌연변이 초고감도 선택적 증폭 방법 및 이를 위한 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004337120A (ja) * 2003-05-19 2004-12-02 Chang Gung Univ 膀胱癌再発検査方法
US7745125B2 (en) * 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
CN101487051B (zh) * 2009-02-24 2011-07-20 广州益善生物技术有限公司 Braf基因突变的检测探针、液相芯片及其检测方法

Also Published As

Publication number Publication date
JP2013501523A (ja) 2013-01-17
TW201111517A (en) 2011-04-01
WO2011019704A2 (en) 2011-02-17
EP2464751B1 (en) 2017-05-24
EP2464751A4 (en) 2013-07-03
EP2464751A2 (en) 2012-06-20
AU2010282632A1 (en) 2012-03-08
IL218021A0 (en) 2012-04-30
AR077844A1 (es) 2011-09-28
CN102575295B (zh) 2016-02-17
US20140248614A1 (en) 2014-09-04
CA2770716A1 (en) 2011-02-17
WO2011019704A3 (en) 2011-07-07
KR20120099630A (ko) 2012-09-11
NZ598166A (en) 2014-03-28
CN102575295A (zh) 2012-07-11

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20200806