AU2010282632A1 - Methods, primers, probes and kits useful for the detection of BRAF mutations - Google Patents

Methods, primers, probes and kits useful for the detection of BRAF mutations Download PDF

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Publication number
AU2010282632A1
AU2010282632A1 AU2010282632A AU2010282632A AU2010282632A1 AU 2010282632 A1 AU2010282632 A1 AU 2010282632A1 AU 2010282632 A AU2010282632 A AU 2010282632A AU 2010282632 A AU2010282632 A AU 2010282632A AU 2010282632 A1 AU2010282632 A1 AU 2010282632A1
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AU
Australia
Prior art keywords
braf
seq
sample
sequence
primer
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Abandoned
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AU2010282632A
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English (en)
Inventor
Kathleen Danenberg
Craig Stephens
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Response Genetics Inc
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Response Genetics Inc
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Application filed by Response Genetics Inc filed Critical Response Genetics Inc
Publication of AU2010282632A1 publication Critical patent/AU2010282632A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Paints Or Removers (AREA)
AU2010282632A 2009-08-11 2010-08-10 Methods, primers, probes and kits useful for the detection of BRAF mutations Abandoned AU2010282632A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US23305409P 2009-08-11 2009-08-11
US61/233,054 2009-08-11
US23707809P 2009-08-26 2009-08-26
US61/237,078 2009-08-26
US30179010P 2010-02-05 2010-02-05
US61/301,790 2010-02-05
PCT/US2010/044997 WO2011019704A2 (en) 2009-08-11 2010-08-10 Methods, primers, probes and kits useful for the detection of braf mutations

Publications (1)

Publication Number Publication Date
AU2010282632A1 true AU2010282632A1 (en) 2012-03-08

Family

ID=43586772

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010282632A Abandoned AU2010282632A1 (en) 2009-08-11 2010-08-10 Methods, primers, probes and kits useful for the detection of BRAF mutations

Country Status (12)

Country Link
US (1) US20140248614A1 (enExample)
EP (1) EP2464751B1 (enExample)
JP (1) JP2013501523A (enExample)
KR (1) KR20120099630A (enExample)
CN (1) CN102575295B (enExample)
AR (1) AR077844A1 (enExample)
AU (1) AU2010282632A1 (enExample)
CA (1) CA2770716A1 (enExample)
IL (1) IL218021A0 (enExample)
NZ (1) NZ598166A (enExample)
TW (1) TW201111517A (enExample)
WO (1) WO2011019704A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6153758B2 (ja) * 2012-04-20 2017-06-28 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット
US10077474B2 (en) * 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
CN102816851A (zh) * 2012-08-29 2012-12-12 苏州旷远生物分子技术有限公司 用于检测braf基因v600e突变的引物、探针、试剂盒及方法
CN102876784B (zh) * 2012-09-13 2014-11-19 周宏灏 焦磷酸测序法检测B-raf基因多态性的试剂盒及方法
EP2711432A1 (en) * 2012-09-21 2014-03-26 Genomica S.A.U. Method for detection of BRAF and PI3K mutations
CA2895828C (en) 2012-12-27 2020-06-02 Quest Diagnostics Investments Incorporated Ddr2 mutations as targetable features of melanoma or basal cell carcinoma
CN103103269B (zh) * 2013-01-18 2015-07-15 陕西佰美基因股份有限公司 一种基于探针熔解技术准确检测braf基因突变的方法
WO2014152185A1 (en) * 2013-03-15 2014-09-25 Abbott Molecular Inc. Multiplex allele detection
KR101378920B1 (ko) * 2013-04-18 2014-03-27 주식회사 현일바이오 Braf 돌연변이의 선택적 검출 방법 및 이를 이용한 키트
KR20160106041A (ko) * 2013-08-14 2016-09-09 퀴아젠 맨스필드, 인코퍼레이티드 Nras 및 braf 핵산의 멀티플렉스 분석을 위한 조성물 및 방법
CN104017887A (zh) * 2014-06-18 2014-09-03 广州好芝生物科技有限公司 人类braf基因突变检测引物对和探针及其试剂盒
CA2954689A1 (en) * 2014-07-11 2016-01-14 Expression Pathology, Inc. Srm/mrm assay for the serine/threonine-protein kinase b-raf (braf)
CN105400900A (zh) * 2015-12-29 2016-03-16 杭州迪安生物技术有限公司 焦磷酸测序技术检测braf基因v600e微量突变试剂盒及其应用
CN105861691A (zh) * 2016-05-06 2016-08-17 北京晋祺生物科技有限公司 一种braf基因突变检测的引物组合物、试剂盒及方法
WO2019004703A1 (ko) * 2017-06-29 2019-01-03 한국과학기술원 신경절 교세포종 및 이와 관련된 질환의 진단, 예방, 또는 치료용 조성물
KR20190038464A (ko) * 2017-09-29 2019-04-08 (재)록원바이오융합연구재단 Ras/braf 돌연변이 검출용 조성물 및 이를 포함하는 키트
CN109161594A (zh) * 2018-08-17 2019-01-08 中山大学达安基因股份有限公司 一种检测braf基因突变的方法及其试剂盒
WO2022119423A1 (ko) * 2020-12-04 2022-06-09 주식회사 제노픽스 폐암 유전자 돌연변이 초고감도 선택적 증폭 방법 및 이를 위한 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004337120A (ja) * 2003-05-19 2004-12-02 Chang Gung Univ 膀胱癌再発検査方法
US7745125B2 (en) * 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
CN101487051B (zh) * 2009-02-24 2011-07-20 广州益善生物技术有限公司 Braf基因突变的检测探针、液相芯片及其检测方法

Also Published As

Publication number Publication date
HK1172931A1 (zh) 2013-05-03
EP2464751B1 (en) 2017-05-24
CA2770716A1 (en) 2011-02-17
CN102575295A (zh) 2012-07-11
AR077844A1 (es) 2011-09-28
TW201111517A (en) 2011-04-01
EP2464751A4 (en) 2013-07-03
NZ598166A (en) 2014-03-28
IL218021A0 (en) 2012-04-30
CN102575295B (zh) 2016-02-17
KR20120099630A (ko) 2012-09-11
JP2013501523A (ja) 2013-01-17
US20140248614A1 (en) 2014-09-04
WO2011019704A2 (en) 2011-02-17
WO2011019704A3 (en) 2011-07-07
EP2464751A2 (en) 2012-06-20

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application