NZ597621A - Sustained delivery formulations of risperidone compounds - Google Patents
Sustained delivery formulations of risperidone compoundsInfo
- Publication number
- NZ597621A NZ597621A NZ59762108A NZ59762108A NZ597621A NZ 597621 A NZ597621 A NZ 597621A NZ 59762108 A NZ59762108 A NZ 59762108A NZ 59762108 A NZ59762108 A NZ 59762108A NZ 597621 A NZ597621 A NZ 597621A
- Authority
- NZ
- New Zealand
- Prior art keywords
- combination
- medicament
- risperidone
- implant
- hydroxyrisperidone
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94034007P | 2007-05-25 | 2007-05-25 | |
| PCT/US2008/001928 WO2008153611A2 (en) | 2007-05-25 | 2008-02-13 | Sustained delivery formulations of risperidone compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ597621A true NZ597621A (en) | 2013-06-28 |
Family
ID=39496214
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ59762108A NZ597621A (en) | 2007-05-25 | 2008-02-13 | Sustained delivery formulations of risperidone compounds |
| NZ581862A NZ581862A (en) | 2007-05-25 | 2008-02-13 | Injectable subcutaneous formulation comprising risperidone capable of forming a solid, microporous implant in a patient |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ581862A NZ581862A (en) | 2007-05-25 | 2008-02-13 | Injectable subcutaneous formulation comprising risperidone capable of forming a solid, microporous implant in a patient |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US10010612B2 (enExample) |
| EP (2) | EP2907524A1 (enExample) |
| JP (3) | JP2010531807A (enExample) |
| CN (1) | CN101801415B (enExample) |
| AU (1) | AU2008262545B2 (enExample) |
| BR (1) | BRPI0811319A2 (enExample) |
| CA (1) | CA2687979C (enExample) |
| ES (1) | ES2562878T3 (enExample) |
| MX (2) | MX354603B (enExample) |
| NZ (2) | NZ597621A (enExample) |
| WO (1) | WO2008153611A2 (enExample) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| WO2008153611A2 (en) | 2007-05-25 | 2008-12-18 | Qlt Usa, Inc. | Sustained delivery formulations of risperidone compounds |
| CN101653422B (zh) * | 2008-08-20 | 2013-03-20 | 山东绿叶制药有限公司 | 利培酮缓释微球、其制备方法和用途 |
| CN101584652B (zh) * | 2009-06-19 | 2012-06-20 | 上海医药集团股份有限公司 | 利培酮缓释凝胶注射剂及其制备方法 |
| WO2011042450A1 (en) | 2009-10-06 | 2011-04-14 | Ascendis Pharma As | Carrier linked paliperidone prodrugs |
| US8758780B2 (en) | 2009-10-06 | 2014-06-24 | Ascendis Pharma As | Subcutaneous paliperidone composition |
| US10350159B2 (en) | 2010-05-31 | 2019-07-16 | Laboratories Farmacéuticos Rovi, S.A. | Paliperidone implant formulation |
| US10335366B2 (en) | 2010-05-31 | 2019-07-02 | Laboratorios Farmacéuticos Rovi, S.A. | Risperidone or paliperidone implant formulation |
| US10285936B2 (en) | 2010-05-31 | 2019-05-14 | Laboratorios Farmacéuticos Rovi, S.A. | Injectable composition with aromatase inhibitor |
| PL2394664T3 (pl) * | 2010-05-31 | 2016-12-30 | Preparat przeciwpsychotyczny do wstrzykiwań o przedłużonym uwalnianiu | |
| US10881605B2 (en) | 2010-05-31 | 2021-01-05 | Laboratorios Farmaceuticos Rovi, S.A. | Methods for the preparation of injectable depot compositions |
| PL2394663T3 (pl) * | 2010-05-31 | 2022-02-21 | Laboratorios Farmaceuticos Rovi, S.A. | Kompozycje do wstrzykiwania implantów biodegradowalnych in-situ |
| US10463607B2 (en) | 2010-05-31 | 2019-11-05 | Laboratorios Farmaceutics Rofi S.A. | Antipsychotic Injectable Depot Composition |
| GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| CN103384528B (zh) * | 2010-11-24 | 2016-04-13 | 杜雷科特公司 | 生物可降解的药物递送组合物 |
| CN102058517A (zh) * | 2010-12-31 | 2011-05-18 | 泰州万全医药科技有限公司 | 一种帕潘立酮缓释剂及其制备方法 |
| ES2607497T3 (es) | 2011-04-25 | 2017-03-31 | Shandong Luye Pharmaceutical Co., Ltd. | Composición de risperidona de microesferas de liberación controlada |
| RS62059B1 (sr) | 2011-05-31 | 2021-07-30 | Laboratorios Farmaceuticos Rovi S A | Kompozicija implanta risperidona i/ili paliperidona |
| PT2529757E (pt) * | 2011-05-31 | 2014-02-27 | Rovi Lab Farmaceut Sa | Formulação para implante de paliperidona |
| DE102013011399A1 (de) | 2012-07-31 | 2014-02-06 | Amw Gmbh | Implantat mit Risperidon |
| EP2900220B1 (en) * | 2012-09-28 | 2018-12-12 | Delpor, Inc. | Device and methods for sustained release of antipsychotic medications |
| US9737605B2 (en) | 2013-03-11 | 2017-08-22 | Durect Corporation | Injectable controlled release composition comprising high viscosity liquid carrier |
| US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
| GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
| US20170266112A1 (en) | 2014-06-11 | 2017-09-21 | Massachusetts Institute Of Technology | Residence structures and related methods |
| CN106573015B (zh) | 2014-06-11 | 2021-11-26 | 麻省理工学院 | 肠溶弹性体 |
| ES2808150T3 (es) | 2014-11-07 | 2021-02-25 | Indivior Uk Ltd | Regímenes de dosificación de buprenorfina |
| CN104398474A (zh) * | 2014-11-21 | 2015-03-11 | 内蒙古医科大学附属医院 | 一种利培酮鼻用凝胶剂及其制备方法 |
| CN107592803B (zh) | 2015-05-01 | 2021-01-22 | 麻省理工学院 | 可触发形状记忆感应装置 |
| MX2018003380A (es) | 2015-09-21 | 2018-08-16 | Teva Pharmaceuticals Int Gmbh | Formulaciones de olanzapina de liberacion sostenida. |
| US20190015415A1 (en) * | 2015-09-30 | 2019-01-17 | Indivior Uk Limited | Methods for treating schizophrenia |
| JP7085473B2 (ja) | 2015-10-23 | 2022-06-16 | リンドラ セラピューティクス, インコーポレイティド | 治療薬の持続放出用の胃内滞留システム及びその使用方法 |
| AU2016355236C1 (en) | 2015-11-16 | 2022-09-22 | Medincell | A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue |
| ES2963058T3 (es) | 2015-12-08 | 2024-03-25 | Lyndra Therapeutics Inc | Configuraciones geométricas para sistemas de residencia gástrica |
| US20170196802A1 (en) * | 2016-01-08 | 2017-07-13 | Abon Pharmaceuticals, Llc | Long Acting Injectable Formulations |
| US12109305B2 (en) | 2016-05-27 | 2024-10-08 | Lyndra Therapeutics, Inc. | Materials architecture for gastric residence systems |
| EP3518902A4 (en) | 2016-09-30 | 2020-07-08 | Lyndra, Inc. | GASTRIC RESIDENCE SYSTEMS FOR LONG-TERM ADMINISTRATION OF ADAMANTANE CLASS MEDICINES |
| CA3048499A1 (en) * | 2017-01-04 | 2018-07-12 | Pharmathen S.A. | Process for preparing biodegradable polymers of high molecular weight |
| WO2018151849A1 (en) | 2017-02-17 | 2018-08-23 | Privo Technologies, Inc. | Particle-based multi-layer therapeutic delivery device and method |
| CA3057438A1 (en) | 2017-03-20 | 2018-09-27 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulaitons |
| US10478403B1 (en) | 2017-05-03 | 2019-11-19 | Privo Technologies, Inc. | Intraoperative topically-applied non-implantable rapid release patch |
| US12023406B2 (en) | 2017-06-09 | 2024-07-02 | Lyndra Therapeutics, Inc. | Gastric residence systems with release rate-modulating films |
| US10646484B2 (en) | 2017-06-16 | 2020-05-12 | Indivior Uk Limited | Methods to treat opioid use disorder |
| US11083678B2 (en) * | 2017-09-20 | 2021-08-10 | Kao Corporation | Hair dyeing method |
| US20190117573A1 (en) * | 2017-10-19 | 2019-04-25 | Hyalo Technologies, LLC | Composition and method of preparation of risperidone extended release preparation |
| EP3803866A4 (en) | 2018-05-24 | 2022-03-16 | Nureva Inc. | METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS |
| WO2019226516A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
| MX2020012459A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
| PE20210047A1 (es) | 2018-06-12 | 2021-01-08 | Farm Rovi Lab Sa | Composicion inyectable |
| US20210386745A1 (en) * | 2019-01-22 | 2021-12-16 | Indivior Uk Limited | Methods for treating schizophrenia |
| BR112022004535A2 (pt) | 2019-09-13 | 2022-06-07 | Medincell S A | Formulações de entrega de fármaco |
| CA3159716A1 (en) * | 2019-12-05 | 2021-06-10 | Fresenius Kabi Usa, Llc | Method for analyzing degarelix and associated products |
| JP2023509463A (ja) * | 2020-01-03 | 2023-03-08 | プリボ テクノロジーズ,インコーポレイティド | 細胞の標的集団の直接注射による治療のためのシステム及び医薬組成物 |
| EP4221688A1 (en) * | 2020-09-30 | 2023-08-09 | Tolmar International Limited | Biodegradable polymer and solvent compositions and systems for extended storage and delivery of active pharmaceutical ingredients |
| WO2022153262A1 (en) | 2021-01-18 | 2022-07-21 | Anton Frenkel | Pharmaceutical dosage form |
| EP4329734A4 (en) | 2021-04-26 | 2025-04-02 | Celanese EVA Performance Polymers LLC | Implantable device for the delayed release of a macromolecular drug compound |
| CN113267579B (zh) * | 2021-05-18 | 2022-08-30 | 中南民族大学 | 一种监测利培酮血药浓度的方法 |
| KR20240117521A (ko) | 2021-07-06 | 2024-08-01 | 마크 하슬레톤 | 세로토닌 재흡수 억제제 금단 증후군의 치료 |
| US12318387B2 (en) | 2021-07-16 | 2025-06-03 | Laboratorios Farmaceuticos Rovi, S.A. | Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition |
| TW202313047A (zh) | 2021-09-21 | 2023-04-01 | 西班牙商禾霏藥品實驗室有限公司 | 抗精神病可注射儲積型組合物 |
| WO2023233051A1 (es) | 2022-05-18 | 2023-12-07 | Laboratorios Farmacéuticos Rovi, S.A. | Composiciones inyectables de liberación prolongada para su uso en el tratamiento con risperidona junto a inhibidores de la enzima cyp2d6 |
| TW202523334A (zh) * | 2023-12-13 | 2025-06-16 | 大陸商長春金賽藥業有限責任公司 | 原位皮下植入的女性激素調節組合物及其製備方法和用途 |
| CN119950530B (zh) * | 2025-01-24 | 2025-12-05 | 山东新时代药业有限公司 | 一种包含他莫昔芬与人参皂苷的纳米乳及其制备方法 |
Family Cites Families (209)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB806876A (en) | 1956-02-16 | 1959-01-07 | Wellcome Found | Improvements in and relating to disposable hypodermic injection devices |
| GB873526A (en) | 1957-08-14 | 1961-07-26 | Upjohn Co | Fluid compositions comprising (acetyl-salicylic acid)-anhydride |
| GB887872A (en) | 1958-06-25 | 1962-01-24 | Upjohn Co | Improvements in or relating to pharmaceutical preparations |
| DE1467938C3 (de) | 1964-05-22 | 1973-12-20 | F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) | Wasserdispergierbares Arzneipräparat für Tiere |
| JPS5078634A (enExample) | 1973-11-16 | 1975-06-26 | ||
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4530840A (en) | 1982-07-29 | 1985-07-23 | The Stolle Research And Development Corporation | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents |
| US4906474A (en) | 1983-03-22 | 1990-03-06 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| US4622219A (en) | 1983-06-17 | 1986-11-11 | Haynes Duncan H | Method of inducing local anesthesia using microdroplets of a general anesthetic |
| US4725442A (en) | 1983-06-17 | 1988-02-16 | Haynes Duncan H | Microdroplets of water-insoluble drugs and injectable formulations containing same |
| US4891225A (en) | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| US4588580B2 (en) | 1984-07-23 | 1999-02-16 | Alaz Corp | Transdermal administration of fentanyl and device therefor |
| US4534974A (en) | 1984-07-31 | 1985-08-13 | Carter-Wallace, Inc. | Pharmaceutical compositions with codeine |
| US4626539A (en) | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
| US4573995A (en) | 1984-10-09 | 1986-03-04 | Alza Corporation | Transdermal therapeutic systems for the administration of naloxone, naltrexone and nalbuphine |
| US4804663A (en) | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| GB8522453D0 (en) | 1985-09-11 | 1985-10-16 | Lilly Industries Ltd | Chewable capsules |
| JPS62298530A (ja) | 1986-06-16 | 1987-12-25 | Otsuka Pharmaceut Co Ltd | 坐薬用医薬組成物 |
| IT1198449B (it) | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5702716A (en) | 1988-10-03 | 1997-12-30 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
| CA2002299A1 (en) | 1988-11-10 | 1990-05-10 | Eugene G. Drust | Compositions for the transdermal delivery of buprenorphine salts |
| US5026556A (en) | 1988-11-10 | 1991-06-25 | Norwich Eaton Pharmaceuticals, Inc. | Compositions for the transdermal delivery of pharmaceutical actives |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| US5324519A (en) | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US5487897A (en) | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
| DE3927113C2 (de) | 1989-08-17 | 1993-11-25 | Dolorgiet Gmbh & Co Kg | Mittel zur Behandlung von schweren Schmerzzuständen und Verfahren zu ihrer Herstellung |
| US5096715A (en) | 1989-11-20 | 1992-03-17 | Alko Ltd. | Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist |
| US5558880A (en) | 1989-12-22 | 1996-09-24 | Janssen Pharmaceutica Inc. | Pharmaceutical and other dosage forms |
| US5660851A (en) | 1989-12-26 | 1997-08-26 | Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem | Ocular inserts |
| AU7880991A (en) | 1990-05-10 | 1991-11-27 | Novo Nordisk A/S | A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols |
| US5069909A (en) | 1990-06-20 | 1991-12-03 | Cygnus Therapeutic Systems | Transdermal administration of buprenorphine |
| JPH0456736U (enExample) | 1990-09-14 | 1992-05-15 | ||
| US5149543A (en) | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| ATE183639T1 (de) | 1991-02-18 | 1999-09-15 | Commw Scient Ind Res Org | Zusammensetzung zur verwendung in der transdermalen verabreichung |
| JP3145742B2 (ja) | 1991-09-19 | 2001-03-12 | 日東電工株式会社 | ゴム系感圧性接着剤とその接着シ―ト |
| AU2605592A (en) | 1991-10-15 | 1993-04-22 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
| WO1993023019A1 (en) | 1992-05-11 | 1993-11-25 | Sri International | Transdermal drug delivery systems and related compositions and methods of use |
| DK0669128T3 (da) | 1992-11-17 | 2000-06-19 | Yoshitomi Pharmaceutical | Sustained-release mikrosfære indeholdende antipsykotikum og fremgangsmåde til at fremstille samme |
| TW376319B (en) | 1993-04-28 | 1999-12-11 | Janssen Pharmaceutica Nv | Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine |
| JP2651106B2 (ja) | 1993-06-28 | 1997-09-10 | 大同鋼板株式会社 | 金属屋根材の葺設構造及びその葺設方法 |
| NZ260909A (en) | 1993-07-05 | 1995-04-27 | Takeda Chemical Industries Ltd | Production of sustained release preparation by allowing a water-soluble polypeptide to permeate into a biodegradable matrix in an aqueous solution |
| US5643605A (en) | 1993-10-25 | 1997-07-01 | Genentech, Inc. | Methods and compositions for microencapsulation of adjuvants |
| ATE212830T1 (de) | 1993-11-19 | 2002-02-15 | Alkermes Inc | Herstellung biologisch abbaubarer, einen biologisch aktiven stoff enthaltender, mikropartikel |
| SK282231B6 (sk) | 1993-11-19 | 2001-12-03 | Janssen Pharmaceutica N. V. | Farmaceutický prostriedok na liečenie psychotických porúch |
| CA2582666C (en) * | 1994-04-08 | 2010-05-25 | Qlt Usa, Inc. | Controlled release implant |
| US5453425A (en) | 1994-07-11 | 1995-09-26 | Janssen Pharmaceutica N.V. | Risperidone oral formulation |
| AU4652596A (en) | 1995-01-09 | 1996-07-31 | Atrix Laboratories, Inc. | Liquid polymer delivery system |
| JP3274579B2 (ja) | 1995-01-12 | 2002-04-15 | 住友製薬株式会社 | 脳血管障害に伴う精神症候治療剤 |
| US5968542A (en) | 1995-06-07 | 1999-10-19 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system as a device |
| US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
| US5747058A (en) | 1995-06-07 | 1998-05-05 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system |
| US7833543B2 (en) | 1995-06-07 | 2010-11-16 | Durect Corporation | High viscosity liquid controlled delivery system and medical or surgical device |
| JP4330175B2 (ja) | 1995-06-07 | 2009-09-16 | デュレクト コーポレイション | 高粘度液体による制御された送達系 |
| US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| US6004969A (en) | 1996-04-15 | 1999-12-21 | National Science Council | Transdermal delivery of buprenorphine preparations |
| EP1210942B1 (en) | 1996-05-07 | 2007-03-21 | Alkermes, Inc. | Microparticles |
| US5792477A (en) | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
| JP4346696B2 (ja) | 1996-05-28 | 2009-10-21 | 久光製薬株式会社 | 経皮治療用装置 |
| ES2172793T3 (es) | 1996-06-17 | 2002-10-01 | Janssen Pharmaceutica Nv | Formas de dosificacion biconvexas de desintegracion rapida. |
| IL130532A0 (en) | 1996-12-20 | 2000-06-01 | Alza Corp | Gel composition and methods |
| DE19701912C1 (de) | 1997-01-10 | 1998-05-14 | Jenapharm Gmbh | Injizierbares Implantat |
| US5948787A (en) | 1997-02-28 | 1999-09-07 | Alza Corporation | Compositions containing opiate analgesics |
| IT1292396B1 (it) | 1997-06-23 | 1999-02-08 | Lisapharma Spa | Cerotto dermico avente elevata resistenza meccanica,flessibilita' trasparenza e conducibilita' elettrica nel trattamento di affezioni |
| US6622036B1 (en) | 2000-02-09 | 2003-09-16 | Cns Response | Method for classifying and treating physiologic brain imbalances using quantitative EEG |
| JP4205231B2 (ja) | 1998-02-10 | 2009-01-07 | ゼネラル・エレクトリック・カンパニイ | バーナ |
| US6733767B2 (en) | 1998-03-19 | 2004-05-11 | Merck & Co., Inc. | Liquid polymeric compositions for controlled release of bioactive substances |
| US7208011B2 (en) | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
| US6261583B1 (en) * | 1998-07-28 | 2001-07-17 | Atrix Laboratories, Inc. | Moldable solid delivery system |
| US6703047B2 (en) | 2001-02-02 | 2004-03-09 | Incept Llc | Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use |
| US6565874B1 (en) * | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US6355657B1 (en) | 1998-12-30 | 2002-03-12 | Atrix Laboratories, Inc. | System for percutaneous delivery of opioid analgesics |
| US6194006B1 (en) | 1998-12-30 | 2001-02-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of microparticles having a selected release profile |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6383471B1 (en) | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
| US6291013B1 (en) | 1999-05-03 | 2001-09-18 | Southern Biosystems, Inc. | Emulsion-based processes for making microparticles |
| DE19923551A1 (de) | 1999-05-21 | 2000-11-30 | Lohmann Therapie Syst Lts | Pharmazeutisches Präparat mit dem Wirkstoff Diamorphin und seine Verwendung in einem Verfahren zur Behandlung der Opiatsucht |
| US6461631B1 (en) | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| DE10190041D2 (de) | 2000-01-11 | 2002-12-05 | Roland Bodmeier | Implantate, Partikel |
| KR100393478B1 (ko) | 2000-03-29 | 2003-08-06 | 주식회사종근당 | 자가유화 매트릭스형 경점막·경피흡수제제 |
| EP1280804B1 (en) | 2000-05-05 | 2004-04-14 | RPG Life Sciences Limited | A process for the preparation of anti-psychotic 3- 2- 4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4h-pyrido 1,2,-a]pyrimidin-4-one |
| US6264987B1 (en) | 2000-05-19 | 2001-07-24 | Alkermes Controlled Therapeutics Inc. Ii | Method for preparing microparticles having a selected polymer molecular weight |
| US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
| WO2002000137A1 (en) | 2000-06-28 | 2002-01-03 | Shukla Atul J | Biodegradable vehicles and delivery systems of biologically active substances |
| DE10035889A1 (de) | 2000-07-24 | 2002-02-14 | Lohmann Therapie Syst Lts | Medizinischer Haftkleber mit einem Gehalt an Zucker-Estern |
| WO2002014286A1 (en) | 2000-08-14 | 2002-02-21 | Teva Pharmaceutical Industries Ltd. | Preparation of risperidone |
| DE10044545A1 (de) | 2000-09-05 | 2002-04-04 | Roland Bodmeier | Retardpartikeldispersion |
| IT250575Y1 (it) | 2000-10-10 | 2003-09-24 | Gimatic Spa | Sistema di guida registrabile per griffe di pinze azionate da unfluido |
| WO2002038185A2 (en) | 2000-11-13 | 2002-05-16 | Atrix Laboratories, Inc. | Injectable sustained release delivery system with loperamide |
| WO2002067895A2 (en) | 2000-11-16 | 2002-09-06 | Durect Corporation | Implant dosage form and use thereof for the delivery of a cholesterol lowering agent |
| JP4724354B2 (ja) | 2001-02-23 | 2011-07-13 | ジェネンテック, インコーポレイテッド | 注射用の崩壊性ポリマー |
| US20040018238A1 (en) | 2001-02-26 | 2004-01-29 | Shukla Atul J | Biodegradable vehicles and delivery systems of biolgically active substances |
| EP1379197A4 (en) | 2001-03-23 | 2009-06-03 | Durect Corp | DISPOSAL OF MEDICINAL PRODUCTS OF DELAYED RELEASE DEVICES IMPLANTED IN MYOKARD TISSUE OR PER ICARDROOM |
| US6558702B2 (en) * | 2001-04-13 | 2003-05-06 | Alkermes Controlled Therapeutics, Inc. | Method of modifying the release profile of sustained release compositions |
| GB0112324D0 (en) | 2001-05-21 | 2001-07-11 | Croda Int Plc | Compounds |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| JP2003063954A (ja) | 2001-08-24 | 2003-03-05 | Saitama Daiichi Seiyaku Kk | リザーバー型貼付剤 |
| CN1703197A (zh) | 2001-11-14 | 2005-11-30 | 阿尔扎有限公司 | 可注射的长效组合物和其使用 |
| JP5170935B2 (ja) | 2001-11-14 | 2013-03-27 | デュレクト コーポレーション | 注入可能なデポー組成物 |
| NZ533436A (en) | 2001-11-14 | 2007-10-26 | Alza Corp | Catheter injectable depot compositons and uses thereof |
| US20040258731A1 (en) | 2001-11-21 | 2004-12-23 | Tsuyoshi Shimoboji | Preparation approriate for cartilage tissue formation |
| AU2003227827B2 (en) | 2002-03-12 | 2008-09-25 | Ethypharm | Composition having gelling properties for the prolonged delivery of bioactive substances |
| US7041320B1 (en) | 2002-05-31 | 2006-05-09 | Biotek, Inc. | High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence |
| MY139059A (en) | 2002-06-24 | 2009-08-28 | Alza Corp | Reusable, spring driven autoinjector |
| AR039729A1 (es) | 2002-06-25 | 2005-03-09 | Alza Corp | Formulaciones de deposito de corta duracion |
| US20040003401A1 (en) | 2002-06-27 | 2004-01-01 | Koninklijke Philips Electronics N.V. | Method and apparatus for using cluster compactness as a measure for generation of additional clusters for stereotyping programs |
| CN1684663A (zh) | 2002-07-31 | 2005-10-19 | 阿尔萨公司 | 可注射的多模式聚合物储库组合物以及其用途 |
| US7097634B2 (en) | 2002-07-31 | 2006-08-29 | Alza Corporation | Injection device providing automatic needle retraction |
| WO2004020439A2 (en) | 2002-08-30 | 2004-03-11 | Sunil Sadanand Nadkarni | Improved process for preparation of risperidone |
| CA2500908A1 (en) | 2002-10-04 | 2004-04-22 | Elan Pharma International Limited | Gamma irradiation of solid nanoparticulate active agents |
| KR20040034996A (ko) | 2002-10-18 | 2004-04-29 | 한미약품 주식회사 | 리스페리돈의 개선된 제조방법 |
| EP1575616A2 (en) | 2002-10-25 | 2005-09-21 | Pfizer Products Inc. | Novel injectable depot formulations |
| DE10250084A1 (de) | 2002-10-25 | 2004-05-06 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| PL377333A1 (pl) | 2002-11-06 | 2006-01-23 | Alza Corporation | Preparaty depot o kontrolowanym uwalnianiu |
| EP2959893A1 (en) | 2002-12-13 | 2015-12-30 | DURECT Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
| WO2004071491A1 (en) | 2003-02-04 | 2004-08-26 | Chrysalis Technologies Incorporated | Aerosol formulations and aerosol delivery of buspirone, buprenorphine, triazolam, cyclobenzaprine and zolpidem |
| ATE495732T1 (de) | 2003-03-26 | 2011-02-15 | Egalet As | Morphin-system mit kontrollierter freisetzung |
| EP1615924A1 (en) | 2003-04-22 | 2006-01-18 | Synthon B.V. | Water soluble salts of risperidone |
| KR20060023140A (ko) | 2003-05-30 | 2006-03-13 | 알자 코포레이션 | 이식성 탄성중합체 데포 조성물, 이의 용도 및 이의제조방법 |
| CN101862455A (zh) | 2003-06-26 | 2010-10-20 | 普西维达公司 | 原位胶凝的药物递送系统 |
| TWI357815B (en) | 2003-06-27 | 2012-02-11 | Euro Celtique Sa | Multiparticulates |
| FI20045223L (fi) | 2004-06-15 | 2005-12-16 | Bioretec Oy | Monitoiminen biohajoava komposiitti ja kirurginen implantti, joka käsittää mainitun komposiitin |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| US20050032781A1 (en) * | 2003-08-06 | 2005-02-10 | Elliot Ehrich | Methods for administering active agents to CYP 2D6 sensitive patients |
| CA2546482A1 (en) | 2003-09-01 | 2005-03-10 | F H Faulding & Co Limited | Compositions and methods for delivery of biologically active agents |
| WO2005037949A2 (en) | 2003-10-07 | 2005-04-28 | Chrysalis Technologies Incorporated | Aerosol formulations of butalbital, lorazepam, ipratropium, baclofen, morphine and scopolamine |
| US20050106214A1 (en) | 2003-11-14 | 2005-05-19 | Guohua Chen | Excipients in drug delivery vehicles |
| US20050281879A1 (en) | 2003-11-14 | 2005-12-22 | Guohua Chen | Excipients in drug delivery vehicles |
| US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
| EP1689465A4 (en) | 2003-12-05 | 2011-10-12 | Zogenix Inc | DEVICE FOR DELIVERY OF A NEEDLELESS INJECTOR USED FOR DRUG DELIVERY |
| EP1711159B1 (en) | 2003-12-30 | 2013-03-20 | Durect Corporation | Solid implants containing a block copolymer for controlled release of a gnrh compound |
| US8329203B2 (en) | 2004-01-12 | 2012-12-11 | The Trustees Of The University Of Pennsylvania | Drug-containing implants and methods of use thereof |
| EP2633853A1 (en) | 2004-01-12 | 2013-09-04 | The Trustees of The University of Pennsylvania | Long-term delivery formulations and methods of use thereof |
| US8221778B2 (en) | 2005-01-12 | 2012-07-17 | The Trustees Of The University Of Pennsylvania | Drug-containing implants and methods of use thereof |
| WO2005089670A1 (en) | 2004-03-15 | 2005-09-29 | Durect Corporation | Pharmaceutical compositions for administration to a sinus |
| IS7290A (is) | 2004-05-28 | 2005-11-29 | Actavis Group | Lyfjasamsetningar sem innihalda risperidone |
| DE602005008247D1 (de) | 2004-06-04 | 2008-08-28 | Camurus Ab | Flüssige depotformulierungen |
| EP1604693A1 (en) | 2004-06-09 | 2005-12-14 | Scil Technology GmbH | In situ forming scaffold, its manufacturing and use |
| GB2418854B (en) | 2004-08-31 | 2009-12-23 | Euro Celtique Sa | Multiparticulates |
| US7780981B2 (en) | 2004-09-13 | 2010-08-24 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
| US8313763B2 (en) | 2004-10-04 | 2012-11-20 | Tolmar Therapeutics, Inc. | Sustained delivery formulations of rapamycin compounds |
| MX2007003789A (es) | 2004-10-04 | 2007-07-20 | Qlt Usa Inc | Suministro ocular de formulaciones polimericas para suministro. |
| CN101146523B (zh) | 2004-10-21 | 2010-12-29 | 杜雷科特公司 | 透皮给药系统 |
| RS53890B1 (sr) | 2004-11-10 | 2015-08-31 | Tolmar Therapeutics, Inc. | Stabilizovan polimerni sistem za isporuku |
| GB2420976B (en) | 2004-11-19 | 2006-12-20 | Zvi Finkelstein | Therapeutic implant |
| AR052155A1 (es) | 2004-12-14 | 2007-03-07 | Novartis Ag | Compuestos organicos |
| US20090092650A1 (en) | 2004-12-15 | 2009-04-09 | Warren Stephen L | Sustained Delivery Formulations of Octreotide Compounds |
| EP1830900A1 (en) | 2004-12-16 | 2007-09-12 | Miv Therapeutics Inc. | Multi-layer drug delivery device and method of manufacturing same |
| US9415034B2 (en) | 2005-01-05 | 2016-08-16 | National Defense Medical Center | Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B) |
| US9168216B2 (en) | 2005-06-17 | 2015-10-27 | Vital Health Sciences Pty. Ltd. | Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof |
| CN103637977A (zh) | 2005-07-18 | 2014-03-19 | 宾夕法尼亚大学理事会 | 含药植入物及其使用方法 |
| US20070020186A1 (en) | 2005-07-22 | 2007-01-25 | Alpex Pharma S.A. | Solid dosage formulations of narcotic drugs having improved buccal adsorption |
| EP1912627B1 (en) | 2005-08-11 | 2016-08-10 | Promedon S.A. | Composition comprising polymeric, water-insoluble, anionic particles, processes and uses |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| CA2627292C (en) | 2005-10-26 | 2012-04-17 | Banner Pharmacaps, Inc. | Hydrophilic vehicle-based dual controlled release matrix system |
| RU2427383C2 (ru) | 2006-01-18 | 2011-08-27 | КьюПиЭс, ЭлЭлСи | Фармацевтические композиции с повышенной стабильностью |
| US20090022798A1 (en) | 2007-07-20 | 2009-01-22 | Abbott Gmbh & Co. Kg | Formulations of nonopioid and confined opioid analgesics |
| US8765178B2 (en) | 2006-07-19 | 2014-07-01 | Watson Laboratories, Inc. | Controlled release formulations and associated methods |
| WO2008038185A2 (en) | 2006-09-25 | 2008-04-03 | Koninklijke Philips Electronics N.V. | Hot water kettle comprising an acoustic member for generating an acoustic signal |
| AU2007304425B2 (en) | 2006-10-02 | 2013-12-05 | Spepharma Ag | Non-mucoadhesive film dosage forms |
| KR20090087441A (ko) | 2006-10-05 | 2009-08-17 | 파나세아 바이오테크 리미티드 | 새로운 형태의 주입형 데포 조성물 및 이를 위한 조제방법 |
| US8076448B2 (en) | 2006-10-11 | 2011-12-13 | Tolmar Therapeutics, Inc. | Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction |
| SI2079767T1 (sl) | 2006-10-11 | 2015-01-30 | Tolmar Therapeutics, Inc. | Priprava biorazgradljivih poliestrov, ki imajo lastnost majhnega izbruha, s superkritično tekočinsko ekstrakcijo |
| GB0620661D0 (en) | 2006-10-18 | 2006-11-29 | Pharmasol Ltd | Novel compounds |
| ES2550014T3 (es) | 2007-02-15 | 2015-11-03 | Tolmar Therapeutics, Inc. | Poli-(lactida/glicolida) de descarga lenta y métodos para producir polímeros |
| KR101521989B1 (ko) | 2007-03-02 | 2015-05-28 | 테이카 세이야쿠 가부시키가이샤 | 경피흡수 의약조성물, 의약조성물 저장유닛 및 이것을 이용하는 경피흡수제제 |
| WO2008124013A1 (en) | 2007-04-03 | 2008-10-16 | Trimeris, Inc. | Novel formulations for delivery of antiviral peptide therapeutics |
| AU2008254538B2 (en) | 2007-05-18 | 2013-11-07 | Durect Corporation | Improved depot formulations |
| WO2008153611A2 (en) | 2007-05-25 | 2008-12-18 | Qlt Usa, Inc. | Sustained delivery formulations of risperidone compounds |
| MX2010002409A (es) | 2007-09-03 | 2010-05-19 | Nanotherapeutics Inc | Composiciones y metodos para la distribucion de farmacos escasamente solubles. |
| DK2200588T3 (da) | 2007-09-25 | 2019-07-01 | Solubest Ltd | Sammensætninger, som omfatter lipofile aktive forbindelser, og fremgangsmåde til fremstilling deraf |
| EP2219622A1 (en) | 2007-12-06 | 2010-08-25 | Durect Corporation | Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition |
| FR2926996B1 (fr) | 2008-01-31 | 2013-06-21 | Ethypharm Sa | Composition pharmaceutique a proprietes gelifiantes contenant un derive de tyrosine |
| US8586103B2 (en) | 2008-02-08 | 2013-11-19 | Foresee Pharmaceuticals, Llc | Non-polymeric compositions for controlled drug delivery |
| AU2009212367B2 (en) | 2008-02-08 | 2013-08-01 | Foresee Pharmaceuticals Co., Ltd. | Composition for sustained release delivery of proteins or peptides |
| JP5286850B2 (ja) | 2008-03-14 | 2013-09-11 | 大日本印刷株式会社 | 液体用紙容器用包装材料およびその包装材料から製造される液体用紙容器 |
| WO2009120889A2 (en) | 2008-03-26 | 2009-10-01 | Alltranz Inc. | Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists |
| EP2291174B1 (en) | 2008-06-03 | 2015-01-28 | Tolmar Therapeutics, Inc. | Flowable composition comprising biocompatible oligomer-polymer compositions |
| US8877225B2 (en) | 2008-06-03 | 2014-11-04 | Tolmar Therapeutics, Inc. | Controlled release copolymer formulation with improved release kinetics |
| US8114429B2 (en) | 2008-09-15 | 2012-02-14 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8257722B2 (en) | 2008-09-15 | 2012-09-04 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8128951B2 (en) | 2008-09-15 | 2012-03-06 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| MY167918A (en) | 2009-04-23 | 2018-09-27 | Londonpharma Ltd | Composition for use in the sublingual delivery of medicaments to humans |
| KR101752014B1 (ko) | 2009-05-01 | 2017-06-28 | 아데어 파마슈티컬스 인코포레이티드 | 고용량 및 저용량 약물들의 조합을 포함하는 구강붕해정 조성물 |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
| FR2949061B1 (fr) | 2009-08-12 | 2013-04-19 | Debregeas Et Associes Pharma | Microgranules flottants |
| CA2780779C (en) | 2009-11-18 | 2020-02-04 | Nektar Therapeutics | Acid salt forms of polymer-drug conjugates and alkoxylation methods |
| US20130023553A1 (en) | 2010-01-12 | 2013-01-24 | Nektar Therapeutics | Pegylated opioids with low potential for abuse and side effects |
| US20130210751A1 (en) | 2010-03-15 | 2013-08-15 | Ipsen Pharma, S.A.S. | Pharmaceutical Compositions of Growth Hormone Secretagogue Receptor Ligands |
| US20110230816A1 (en) | 2010-03-18 | 2011-09-22 | Tyco Healthcare Group Lp | Gels for Transdermal Delivery |
| PL2394664T3 (pl) | 2010-05-31 | 2016-12-30 | Preparat przeciwpsychotyczny do wstrzykiwań o przedłużonym uwalnianiu | |
| PL2394663T3 (pl) | 2010-05-31 | 2022-02-21 | Laboratorios Farmaceuticos Rovi, S.A. | Kompozycje do wstrzykiwania implantów biodegradowalnych in-situ |
| EP2585092A1 (en) | 2010-06-24 | 2013-05-01 | Torrent Pharmaceuticals Limited | Pharmaceutical composition containing goserelin for in-situ implant |
| EP2619212B1 (en) | 2010-09-21 | 2016-01-06 | Purdue Pharma L.P. | Buprenorphine analogs as opioid receptor agonists and/or antagonists |
| ES2528650T3 (es) | 2010-11-17 | 2015-02-11 | Hexal Ag | Sistema terapéutico transdérmico que comprende buprenorfina |
| CN103384528B (zh) | 2010-11-24 | 2016-04-13 | 杜雷科特公司 | 生物可降解的药物递送组合物 |
| EP2643020A4 (en) | 2010-11-26 | 2014-11-12 | Univ Witwatersrand Jhb | ACTIVE RELEASE DEVICE |
| RS62059B1 (sr) | 2011-05-31 | 2021-07-30 | Laboratorios Farmaceuticos Rovi S A | Kompozicija implanta risperidona i/ili paliperidona |
| SG10201604754VA (en) | 2011-12-12 | 2016-08-30 | Lohmann Therapie Syst Lts | Transdermal delivery system comprising buprenorphine |
| US9468599B2 (en) | 2011-12-27 | 2016-10-18 | Cmpd Licensing, Llc | Composition and method for compounded therapy |
| US20140134261A1 (en) | 2012-08-21 | 2014-05-15 | Trinity Laboratories, Inc. | Pharmaceutical Compositions Comprising Capsaicin Esters for Treating Pain and Cold Sores |
| RU2513514C1 (ru) | 2012-11-23 | 2014-04-20 | Общество с ограниченной ответственностью "НПК "Трифарма" | Фармацевтическая композиция, содержащая налбуфина гидрохлорид, ее применение для лечения болевого синдрома средней и высокой интенсивности и способ получения фармацевтической композиции |
| CN103142458B (zh) | 2013-01-22 | 2015-09-09 | 莱普德制药有限公司 | 无成瘾性镇痛缓释递药系统的组方与制备方法 |
| US9737605B2 (en) | 2013-03-11 | 2017-08-22 | Durect Corporation | Injectable controlled release composition comprising high viscosity liquid carrier |
| US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
| US9393211B2 (en) | 2013-03-15 | 2016-07-19 | Oakwood Laboratories LLC | High drug load buprenorphine microspheres and method of producing same |
| IN2013MU03658A (enExample) | 2013-11-21 | 2015-09-25 | Akanksha Bindeshwari Prasad Yadav | |
| US10525171B2 (en) | 2014-01-24 | 2020-01-07 | The Spectranetics Corporation | Coatings for medical devices |
-
2008
- 2008-02-13 WO PCT/US2008/001928 patent/WO2008153611A2/en not_active Ceased
- 2008-02-13 MX MX2013002428A patent/MX354603B/es unknown
- 2008-02-13 ES ES08725543.6T patent/ES2562878T3/es active Active
- 2008-02-13 NZ NZ59762108A patent/NZ597621A/xx not_active IP Right Cessation
- 2008-02-13 CA CA2687979A patent/CA2687979C/en active Active
- 2008-02-13 EP EP15000500.7A patent/EP2907524A1/en not_active Ceased
- 2008-02-13 JP JP2010509326A patent/JP2010531807A/ja active Pending
- 2008-02-13 AU AU2008262545A patent/AU2008262545B2/en not_active Ceased
- 2008-02-13 MX MX2009012781A patent/MX337286B/es active IP Right Grant
- 2008-02-13 EP EP08725543.6A patent/EP2152315B1/en active Active
- 2008-02-13 US US12/602,058 patent/US10010612B2/en active Active
- 2008-02-13 BR BRPI0811319 patent/BRPI0811319A2/pt not_active Application Discontinuation
- 2008-02-13 NZ NZ581862A patent/NZ581862A/en not_active IP Right Cessation
- 2008-02-13 CN CN200880100394.0A patent/CN101801415B/zh not_active Expired - Fee Related
-
2013
- 2013-04-18 JP JP2013087247A patent/JP5795606B2/ja not_active Expired - Fee Related
-
2014
- 2014-09-18 US US14/490,082 patent/US9186413B2/en active Active
- 2014-09-18 US US14/490,034 patent/US9180197B2/en active Active
- 2014-09-25 JP JP2014194758A patent/JP2014240436A/ja not_active Withdrawn
-
2017
- 2017-12-29 US US15/858,525 patent/US10376590B2/en active Active
-
2019
- 2019-07-11 US US16/509,287 patent/US11013809B2/en active Active
-
2021
- 2021-04-22 US US17/237,207 patent/US11712475B2/en active Active
-
2022
- 2022-12-19 US US18/083,774 patent/US20230135427A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ597621A (en) | Sustained delivery formulations of risperidone compounds | |
| Qin et al. | Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections | |
| Cheng et al. | Strontium ion-functionalized nano-hydroxyapatite/chitosan composite microspheres promote osteogenesis and angiogenesis for bone regeneration | |
| WO2007038246A3 (en) | Solid polymer delivery compositions and methods for use thereof | |
| Bao et al. | 3D biomimetic artificial bone scaffolds with dual-cytokines spatiotemporal delivery for large weight-bearing bone defect repair | |
| WO2009044403A3 (en) | Injectable biodegradable polymer compositions for soft tissue repair and augmentation | |
| Lanao et al. | Bone response to fast-degrading, injectable calcium phosphate cements containing PLGA microparticles | |
| Azarmgin et al. | Polyurethanes and their biomedical applications | |
| Ferretti et al. | Controlled in vivo degradation of genipin crosslinked polyethylene glycol hydrogels within osteochondral defects | |
| NZ604026A (en) | Injectable flowable composition comprising buprenorphine | |
| EA027046B1 (ru) | Биоразлагаемая композиция для доставки лекарственных средств, способ ее получения и ее применение | |
| MY161930A (en) | Antipsychotic injectable depot composition | |
| AU2000202A (en) | Methods and compositions for enhanced delivery of bioactive molecules | |
| WO2010005723A3 (en) | Drug loaded polymeric nanoparticles and methods of making and using same | |
| WO2011089604A3 (en) | Material and method for treating internal cavities | |
| JP2008524235A5 (enExample) | ||
| WO2006050091A3 (en) | Bioactive wound dressings and implantable devices and methods of use | |
| WO2008051881A3 (en) | Bioabsorbable medical device with coating | |
| Li et al. | Advanced hydrogel material for meniscus repair | |
| Sun et al. | Hydrogels promote periodontal regeneration | |
| Wang | Smart materials for tissue engineering: applications | |
| Cao et al. | Functional hydrogel interfaces for cartilage and bone regeneration | |
| Baawad et al. | Polysaccharide-based composite scaffolds for osteochondral and enthesis regeneration | |
| Dallaev | Smart and biodegradable polymers in tissue engineering and interventional devices: A brief review | |
| Wang et al. | Application and progress of 3D printed biomaterials in osteoporosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 13 FEB 2015 BY CPA GLOBAL Effective date: 20131029 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2016 BY CPA GLOBAL Effective date: 20150116 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2017 BY COMPUTER PACKAGES INC Effective date: 20160119 |
|
| ASS | Change of ownership |
Owner name: INDIVIOR UK LIMITED, GB Effective date: 20160414 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2018 BY COMPUTER PACKAGES INC Effective date: 20170118 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2019 BY COMPUTER PACKAGES INC Effective date: 20180118 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2020 BY CPA GLOBAL Effective date: 20181227 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2021 BY CPA GLOBAL Effective date: 20200102 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2022 BY COMPUTER PACKAGES INC Effective date: 20210119 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2023 BY COMPUTER PACKAGES INC Effective date: 20220117 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2024 BY COMPUTER PACKAGES INC Effective date: 20230117 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 13 FEB 2025 BY COMPUTER PACKAGES INC Effective date: 20240117 |
|
| LAPS | Patent lapsed |