NZ594212A - Method for production of lactoferrin - Google Patents
Method for production of lactoferrinInfo
- Publication number
- NZ594212A NZ594212A NZ594212A NZ59421210A NZ594212A NZ 594212 A NZ594212 A NZ 594212A NZ 594212 A NZ594212 A NZ 594212A NZ 59421210 A NZ59421210 A NZ 59421210A NZ 594212 A NZ594212 A NZ 594212A
- Authority
- NZ
- New Zealand
- Prior art keywords
- lactoferrin
- milk
- angiogenin
- endotoxins
- lps
- Prior art date
Links
- 108010063045 Lactoferrin Proteins 0.000 title abstract 4
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title abstract 4
- 229940078795 lactoferrin Drugs 0.000 title abstract 4
- 235000021242 lactoferrin Nutrition 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000010445 Lactoferrin Human genes 0.000 title 1
- 239000002158 endotoxin Substances 0.000 abstract 4
- 102100032241 Lactotransferrin Human genes 0.000 abstract 3
- 102100022987 Angiogenin Human genes 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 108010072788 angiogenin Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 235000013336 milk Nutrition 0.000 abstract 2
- 239000008267 milk Substances 0.000 abstract 2
- 210000004080 milk Anatomy 0.000 abstract 2
- 239000002994 raw material Substances 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 101710093543 Probable non-specific lipid-transfer protein Proteins 0.000 abstract 1
- 239000005862 Whey Substances 0.000 abstract 1
- 239000008351 acetate buffer Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 210000003022 colostrum Anatomy 0.000 abstract 1
- 235000021277 colostrum Nutrition 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 238000009928 pasteurization Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 235000020183 skimmed milk Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/30—Ion-exchange
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/34—Membrane process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20208809P | 2009-01-28 | 2009-01-28 | |
| PCT/IB2010/000149 WO2010112988A1 (en) | 2009-01-28 | 2010-01-28 | Method for production of lactoferrin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ594212A true NZ594212A (en) | 2013-01-25 |
Family
ID=41818728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ594212A NZ594212A (en) | 2009-01-28 | 2010-01-28 | Method for production of lactoferrin |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9115211B2 (enExample) |
| EP (1) | EP2391225B1 (enExample) |
| JP (1) | JP5718254B2 (enExample) |
| CN (1) | CN102348387B (enExample) |
| AU (1) | AU2010231075B2 (enExample) |
| CA (1) | CA2750701C (enExample) |
| DK (1) | DK2391225T3 (enExample) |
| ES (1) | ES2805279T3 (enExample) |
| NZ (1) | NZ594212A (enExample) |
| PL (1) | PL2391225T3 (enExample) |
| RU (1) | RU2579661C2 (enExample) |
| WO (1) | WO2010112988A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013204858B2 (en) * | 2012-10-08 | 2015-06-25 | Saputo Dairy Australia Pty Limited | Improved process for purifying milk proteins and products thereof |
| AU2013204850B2 (en) * | 2012-10-08 | 2015-06-25 | Murray Goulburn Co-Operative Co. Limited | Improved process for purifying milk proteins and products thereof |
| RO130063A8 (ro) | 2014-08-28 | 2017-06-30 | Romvac Company S.A. | Producerea şi utilizarea ovotransferinei moderne () |
| JPWO2016136904A1 (ja) * | 2015-02-26 | 2017-12-07 | 味の素株式会社 | チーズの製造方法及びチーズ改質用の製剤 |
| FR3046603B1 (fr) | 2016-01-11 | 2017-12-29 | Michelin & Cie | Procede de modification d'un caoutchouc naturel et caoutchouc naturel modifie |
| CN117942405A (zh) | 2016-02-25 | 2024-04-30 | 应用生物实验室公司 | 保护空气传播的病原体和刺激物的组合物和方法 |
| US12447166B2 (en) * | 2016-02-25 | 2025-10-21 | Applied Biological Laboratories, Inc. | Compositions and methods for protecting against airborne pathogens and irritants |
| CN112996806A (zh) * | 2018-11-06 | 2021-06-18 | 安赫尔工程建模有限责任公司 | 从奶、初乳和酸乳清或甜乳清中制备高纯度乳铁蛋白和乳过氧化物酶的方法 |
| JPWO2021153508A1 (enExample) | 2020-01-30 | 2021-08-05 | ||
| AU2020203454B1 (en) * | 2020-05-26 | 2021-07-22 | HPS Tech Pty Ltd | Processing protein |
| FR3115037B1 (fr) | 2020-10-12 | 2025-02-21 | Cie Laitiere Europeenne | Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue |
| UY39909A (es) * | 2021-08-23 | 2023-03-31 | Lactea Therapeutics Llc | Composiciones de lactoferrina y métodos de uso |
| IL311036A (en) * | 2021-08-23 | 2024-04-01 | Lactea Therapeutics Llc | Lactoferrin compositions and methods of use |
| US20250136666A1 (en) * | 2021-11-16 | 2025-05-01 | Noumi Limited | A method for producing a lactoferrin powder and uses thereof |
| DE202023102334U1 (de) | 2023-04-28 | 2023-06-07 | Mercurius Production Gmbh | Lactoferrin und Vorrichtung zu dessen Herstellung |
| PL444766A1 (pl) * | 2023-05-07 | 2024-11-12 | Polmlek Spółka Z Ograniczoną Odpowiedzialnością | Sposób uzyskiwania laktoferyny w proszku z surowego mleka |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE61701B1 (en) * | 1986-07-17 | 1994-11-30 | Morinaga Milk Industry Co Ltd | Process for producing bovine lactoferrin in high purity |
| US5571697A (en) * | 1989-05-05 | 1996-11-05 | Baylor College Of Medicine Texas Medical Center | Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus |
| JP2686831B2 (ja) * | 1989-09-22 | 1997-12-08 | 雪印乳業株式会社 | 鉄結合性蛋白質を分離、精製し、採取する方法 |
| US6096870A (en) * | 1994-01-05 | 2000-08-01 | Sepragen Corporation | Sequential separation of whey |
| JPH09509165A (ja) * | 1994-02-16 | 1997-09-16 | ファーミング ベスローテン フェンノートシャップ | ミルクからのラクトフェリンの分離 |
| JPH08217693A (ja) * | 1995-02-17 | 1996-08-27 | Yoshihisa Naito | 新規医薬組成物 |
| JP2974604B2 (ja) * | 1996-01-23 | 1999-11-10 | 雪印乳業株式会社 | 塩基性タンパク質組成物、塩基性ペプチド組成物及びその利用 |
| JPH1059864A (ja) * | 1996-08-15 | 1998-03-03 | Morinaga Milk Ind Co Ltd | 経口がん転移抑制剤 |
| JP2002326950A (ja) * | 2001-05-02 | 2002-11-15 | Meiji Milk Prod Co Ltd | 炎症性サイトカイン産生抑制剤 |
| US20030096736A1 (en) * | 2001-05-09 | 2003-05-22 | Kruzel Marian L. | Lactoferrin for age related disorders in humans |
| WO2003094952A1 (en) * | 2002-05-10 | 2003-11-20 | Agennix Incorporated | Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases |
| AU2003233583A1 (en) * | 2002-05-24 | 2003-12-12 | Agennix Incorporated | Oral lactoferrin in the treatment of respiratory disorders |
| CA2542291A1 (en) * | 2004-02-03 | 2005-08-18 | Kurume University | Method for separating/refining cationic protein |
| CA2608281A1 (en) | 2005-05-13 | 2006-11-16 | Crea Biopharma Inc. | New purification method of lactoferrin |
| JP5087297B2 (ja) * | 2007-03-05 | 2012-12-05 | 森永乳業株式会社 | インターロイキン−１１産生促進剤 |
| CN101117351B (zh) * | 2007-04-30 | 2010-08-18 | 北京济普霖生物技术有限公司 | 一种从转基因牛乳中纯化重组人乳铁蛋白的方法 |
| NZ583234A (en) | 2007-07-10 | 2012-06-29 | Glanbia Nutritionals | Method for removing endotoxin from proteins |
-
2010
- 2010-01-28 RU RU2011135536/10A patent/RU2579661C2/ru active
- 2010-01-28 CN CN201080010953.6A patent/CN102348387B/zh not_active Expired - Fee Related
- 2010-01-28 ES ES10703352T patent/ES2805279T3/es active Active
- 2010-01-28 PL PL10703352T patent/PL2391225T3/pl unknown
- 2010-01-28 DK DK10703352.4T patent/DK2391225T3/da active
- 2010-01-28 CA CA2750701A patent/CA2750701C/en not_active Expired - Fee Related
- 2010-01-28 AU AU2010231075A patent/AU2010231075B2/en not_active Ceased
- 2010-01-28 WO PCT/IB2010/000149 patent/WO2010112988A1/en not_active Ceased
- 2010-01-28 JP JP2011546988A patent/JP5718254B2/ja not_active Expired - Fee Related
- 2010-01-28 US US13/146,798 patent/US9115211B2/en active Active - Reinstated
- 2010-01-28 NZ NZ594212A patent/NZ594212A/xx not_active IP Right Cessation
- 2010-01-28 EP EP10703352.4A patent/EP2391225B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2011135536A (ru) | 2013-03-10 |
| RU2579661C2 (ru) | 2016-04-10 |
| DK2391225T3 (da) | 2020-07-20 |
| EP2391225B1 (en) | 2020-05-06 |
| EP2391225A1 (en) | 2011-12-07 |
| WO2010112988A1 (en) | 2010-10-07 |
| JP2012516319A (ja) | 2012-07-19 |
| CA2750701C (en) | 2018-02-13 |
| JP5718254B2 (ja) | 2015-05-13 |
| CN102348387A (zh) | 2012-02-08 |
| CA2750701A1 (en) | 2010-10-07 |
| CN102348387B (zh) | 2014-12-31 |
| AU2010231075B2 (en) | 2015-06-11 |
| ES2805279T3 (es) | 2021-02-11 |
| AU2010231075A1 (en) | 2011-08-18 |
| US9115211B2 (en) | 2015-08-25 |
| PL2391225T3 (pl) | 2020-11-16 |
| US20110301077A1 (en) | 2011-12-08 |
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