CN102348387B - 生产乳转铁蛋白的方法 - Google Patents

生产乳转铁蛋白的方法 Download PDF

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Publication number
CN102348387B
CN102348387B CN201080010953.6A CN201080010953A CN102348387B CN 102348387 B CN102348387 B CN 102348387B CN 201080010953 A CN201080010953 A CN 201080010953A CN 102348387 B CN102348387 B CN 102348387B
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lactotransferrin
lps
pharmaceutical composition
iron
solution
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CN102348387A (zh
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让-保罗·佩罗丹
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/30—Ion-exchange
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/34—Membrane process
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201080010953.6A 2009-01-28 2010-01-28 生产乳转铁蛋白的方法 Expired - Fee Related CN102348387B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20208809P 2009-01-28 2009-01-28
US61/202,088 2009-01-28
PCT/IB2010/000149 WO2010112988A1 (en) 2009-01-28 2010-01-28 Method for production of lactoferrin

Publications (2)

Publication Number Publication Date
CN102348387A CN102348387A (zh) 2012-02-08
CN102348387B true CN102348387B (zh) 2014-12-31

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CN201080010953.6A Expired - Fee Related CN102348387B (zh) 2009-01-28 2010-01-28 生产乳转铁蛋白的方法

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US (1) US9115211B2 (enExample)
EP (1) EP2391225B1 (enExample)
JP (1) JP5718254B2 (enExample)
CN (1) CN102348387B (enExample)
AU (1) AU2010231075B2 (enExample)
CA (1) CA2750701C (enExample)
DK (1) DK2391225T3 (enExample)
ES (1) ES2805279T3 (enExample)
NZ (1) NZ594212A (enExample)
PL (1) PL2391225T3 (enExample)
RU (1) RU2579661C2 (enExample)
WO (1) WO2010112988A1 (enExample)

Families Citing this family (16)

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AU2013204858B2 (en) * 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof
AU2013204850B2 (en) * 2012-10-08 2015-06-25 Murray Goulburn Co-Operative Co. Limited Improved process for purifying milk proteins and products thereof
RO130063A8 (ro) 2014-08-28 2017-06-30 Romvac Company S.A. Producerea şi utilizarea ovotransferinei moderne ()
JPWO2016136904A1 (ja) * 2015-02-26 2017-12-07 味の素株式会社 チーズの製造方法及びチーズ改質用の製剤
FR3046603B1 (fr) 2016-01-11 2017-12-29 Michelin & Cie Procede de modification d'un caoutchouc naturel et caoutchouc naturel modifie
CN117942405A (zh) 2016-02-25 2024-04-30 应用生物实验室公司 保护空气传播的病原体和刺激物的组合物和方法
US12447166B2 (en) * 2016-02-25 2025-10-21 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants
CN112996806A (zh) * 2018-11-06 2021-06-18 安赫尔工程建模有限责任公司 从奶、初乳和酸乳清或甜乳清中制备高纯度乳铁蛋白和乳过氧化物酶的方法
JPWO2021153508A1 (enExample) 2020-01-30 2021-08-05
AU2020203454B1 (en) * 2020-05-26 2021-07-22 HPS Tech Pty Ltd Processing protein
FR3115037B1 (fr) 2020-10-12 2025-02-21 Cie Laitiere Europeenne Procédé de purification de fraction de protéines cationiques et fraction ainsi obtenue
UY39909A (es) * 2021-08-23 2023-03-31 Lactea Therapeutics Llc Composiciones de lactoferrina y métodos de uso
IL311036A (en) * 2021-08-23 2024-04-01 Lactea Therapeutics Llc Lactoferrin compositions and methods of use
US20250136666A1 (en) * 2021-11-16 2025-05-01 Noumi Limited A method for producing a lactoferrin powder and uses thereof
DE202023102334U1 (de) 2023-04-28 2023-06-07 Mercurius Production Gmbh Lactoferrin und Vorrichtung zu dessen Herstellung
PL444766A1 (pl) * 2023-05-07 2024-11-12 Polmlek Spółka Z Ograniczoną Odpowiedzialnością Sposób uzyskiwania laktoferyny w proszku z surowego mleka

Citations (3)

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WO2006119644A1 (en) * 2005-05-13 2006-11-16 Crea Biopharma Inc. New purification method of lactoferrin
CN101117351A (zh) * 2007-04-30 2008-02-06 北京济普霖生物技术有限公司 一种从转基因牛乳中纯化重组人乳铁蛋白的方法
WO2009009706A1 (en) * 2007-07-10 2009-01-15 Glanbia Nutritionals Method for removing endotoxin from proteins

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US5571697A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Texas Medical Center Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus
JP2686831B2 (ja) * 1989-09-22 1997-12-08 雪印乳業株式会社 鉄結合性蛋白質を分離、精製し、採取する方法
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006119644A1 (en) * 2005-05-13 2006-11-16 Crea Biopharma Inc. New purification method of lactoferrin
CN101117351A (zh) * 2007-04-30 2008-02-06 北京济普霖生物技术有限公司 一种从转基因牛乳中纯化重组人乳铁蛋白的方法
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Also Published As

Publication number Publication date
NZ594212A (en) 2013-01-25
RU2011135536A (ru) 2013-03-10
RU2579661C2 (ru) 2016-04-10
DK2391225T3 (da) 2020-07-20
EP2391225B1 (en) 2020-05-06
EP2391225A1 (en) 2011-12-07
WO2010112988A1 (en) 2010-10-07
JP2012516319A (ja) 2012-07-19
CA2750701C (en) 2018-02-13
JP5718254B2 (ja) 2015-05-13
CN102348387A (zh) 2012-02-08
CA2750701A1 (en) 2010-10-07
AU2010231075B2 (en) 2015-06-11
ES2805279T3 (es) 2021-02-11
AU2010231075A1 (en) 2011-08-18
US9115211B2 (en) 2015-08-25
PL2391225T3 (pl) 2020-11-16
US20110301077A1 (en) 2011-12-08

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