NZ591311A - Treatment of acute lymphoblastic leukemia with a CD19 CD3 bispecific single chain antibody construct - Google Patents

Treatment of acute lymphoblastic leukemia with a CD19 CD3 bispecific single chain antibody construct

Info

Publication number
NZ591311A
NZ591311A NZ591311A NZ59131109A NZ591311A NZ 591311 A NZ591311 A NZ 591311A NZ 591311 A NZ591311 A NZ 591311A NZ 59131109 A NZ59131109 A NZ 59131109A NZ 591311 A NZ591311 A NZ 591311A
Authority
NZ
New Zealand
Prior art keywords
treatment
single chain
chain antibody
lymphoblastic leukemia
acute lymphoblastic
Prior art date
Application number
NZ591311A
Other languages
English (en)
Inventor
Gerhard Zugmaier
Evelyn Degenhard
Original Assignee
Micromet Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41692882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ591311(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Micromet Ag filed Critical Micromet Ag
Publication of NZ591311A publication Critical patent/NZ591311A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ591311A 2008-11-07 2009-11-06 Treatment of acute lymphoblastic leukemia with a CD19 CD3 bispecific single chain antibody construct NZ591311A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US18329109P 2009-06-02 2009-06-02
PCT/EP2009/007970 WO2010052014A1 (en) 2008-11-07 2009-11-06 Treatment of acute lymphoblastic leukemia

Publications (1)

Publication Number Publication Date
NZ591311A true NZ591311A (en) 2012-10-26

Family

ID=41692882

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ591311A NZ591311A (en) 2008-11-07 2009-11-06 Treatment of acute lymphoblastic leukemia with a CD19 CD3 bispecific single chain antibody construct

Country Status (26)

Country Link
US (3) US20130323247A1 (https=)
EP (2) EP2982696B1 (https=)
JP (2) JP5647132B2 (https=)
KR (1) KR101695327B1 (https=)
CN (2) CN102209728A (https=)
AU (4) AU2009313040B2 (https=)
BR (1) BRPI0921482B1 (https=)
CA (1) CA2742249C (https=)
CY (2) CY1117033T1 (https=)
DK (2) DK2342227T3 (https=)
ES (2) ES2558434T3 (https=)
HR (2) HRP20151168T1 (https=)
HU (2) HUE043326T2 (https=)
IL (1) IL212652A (https=)
LT (1) LT2982696T (https=)
ME (2) ME02363B (https=)
MX (1) MX2011002927A (https=)
NZ (1) NZ591311A (https=)
PL (2) PL2342227T3 (https=)
PT (2) PT2982696T (https=)
RS (2) RS58827B1 (https=)
RU (1) RU2536940C2 (https=)
SI (2) SI2342227T1 (https=)
SM (2) SMT201900278T1 (https=)
WO (1) WO2010052014A1 (https=)
ZA (1) ZA201103255B (https=)

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Also Published As

Publication number Publication date
EP2982696A2 (en) 2016-02-10
KR101695327B1 (ko) 2017-01-11
DK2982696T3 (da) 2019-05-27
SMT201500328B (it) 2016-02-25
SI2982696T1 (sl) 2019-06-28
AU2017219083A1 (en) 2017-09-14
RU2011122819A (ru) 2012-12-20
DK2342227T3 (en) 2016-02-15
US20190300609A1 (en) 2019-10-03
US20130323247A1 (en) 2013-12-05
AU2015238784A1 (en) 2015-10-29
JP5955921B2 (ja) 2016-07-20
JP2015057417A (ja) 2015-03-26
AU2018260815B2 (en) 2020-03-05
WO2010052014A1 (en) 2010-05-14
BRPI0921482A2 (pt) 2016-01-12
ES2558434T3 (es) 2016-02-04
HUE028175T2 (en) 2016-12-28
CN107184977A (zh) 2017-09-22
ZA201103255B (en) 2013-12-23
EP2982696B1 (en) 2019-03-27
EP2982696A3 (en) 2016-02-17
CY1122366T1 (el) 2021-01-27
EP2342227B1 (en) 2015-10-07
ES2727585T3 (es) 2019-10-17
ME02363B (me) 2016-06-20
HRP20190912T1 (hr) 2019-07-26
CY1117033T1 (el) 2017-04-05
BRPI0921482B1 (pt) 2022-09-20
US20240109964A1 (en) 2024-04-04
AU2009313040A1 (en) 2010-05-14
AU2009313040B2 (en) 2015-07-09
HK1220705A1 (en) 2017-05-12
HRP20151168T1 (hr) 2015-12-04
MX2011002927A (es) 2011-04-11
LT2982696T (lt) 2019-06-10
HK1158668A1 (en) 2012-07-20
RS54456B1 (sr) 2016-06-30
CN102209728A (zh) 2011-10-05
RS58827B1 (sr) 2019-07-31
PT2342227E (pt) 2015-11-13
IL212652A0 (en) 2011-07-31
US11597766B2 (en) 2023-03-07
EP2342227A1 (en) 2011-07-13
AU2018260815A1 (en) 2018-11-22
CA2742249A1 (en) 2010-05-14
CA2742249C (en) 2020-07-21
PT2982696T (pt) 2019-06-04
KR20110091668A (ko) 2011-08-12
JP2012508164A (ja) 2012-04-05
AU2017219083B2 (en) 2018-08-09
SMT201900278T1 (it) 2019-07-11
ME03480B (me) 2020-01-20
PL2982696T3 (pl) 2019-08-30
BRPI0921482A8 (pt) 2017-07-11
PL2342227T3 (pl) 2016-04-29
SI2342227T1 (sl) 2015-12-31
IL212652A (en) 2015-05-31
JP5647132B2 (ja) 2014-12-24
RU2536940C2 (ru) 2014-12-27
HUE043326T2 (hu) 2019-08-28

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