CY1122366T1 - Θεραπεια της οξειας λεμφοβλαστικης λευχαιμιας - Google Patents

Θεραπεια της οξειας λεμφοβλαστικης λευχαιμιας

Info

Publication number
CY1122366T1
CY1122366T1 CY20191100527T CY191100527T CY1122366T1 CY 1122366 T1 CY1122366 T1 CY 1122366T1 CY 20191100527 T CY20191100527 T CY 20191100527T CY 191100527 T CY191100527 T CY 191100527T CY 1122366 T1 CY1122366 T1 CY 1122366T1
Authority
CY
Cyprus
Prior art keywords
lymphoblastic leukemia
acute lymphoblastic
treatment
eradicating
ameliorating
Prior art date
Application number
CY20191100527T
Other languages
English (en)
Inventor
Gerhard Zugmaier
Evelyn Degenhard
Original Assignee
Amgen Research (Munich) Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41692882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1122366(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Research (Munich) Gmbh filed Critical Amgen Research (Munich) Gmbh
Publication of CY1122366T1 publication Critical patent/CY1122366T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε μια μέθοδο για τη θεραπεία, καλυτέρευση ή εξάλειψη της οξείας λεμφοβλαστικής λευχαιμίας (ΟΛΛ), με τη μέθοδο να περιλαμβάνει τη χορήγηση μιας φαρμακευτικής σύνθεσης που περιλαμβάνει ένα κατασκεύασμα του διειδικού αντισώματος μονής αλύσου CD19xCD3 σε έναν ενήλικα ασθενή που χρήζει αυτού.
CY20191100527T 2008-11-07 2019-05-17 Θεραπεια της οξειας λεμφοβλαστικης λευχαιμιας CY1122366T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US18329109P 2009-06-02 2009-06-02
PCT/EP2009/007970 WO2010052014A1 (en) 2008-11-07 2009-11-06 Treatment of acute lymphoblastic leukemia
EP09760483.9A EP2342227B1 (en) 2008-11-07 2009-11-06 Treatment of acute lymphoblastic leukemia

Publications (1)

Publication Number Publication Date
CY1122366T1 true CY1122366T1 (el) 2021-01-27

Family

ID=41692882

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20151101123T CY1117033T1 (el) 2008-11-07 2015-12-09 Αγωγη εναντι οξειας λεμφοβλαστικης λευχαιμιας
CY20191100527T CY1122366T1 (el) 2008-11-07 2019-05-17 Θεραπεια της οξειας λεμφοβλαστικης λευχαιμιας

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY20151101123T CY1117033T1 (el) 2008-11-07 2015-12-09 Αγωγη εναντι οξειας λεμφοβλαστικης λευχαιμιας

Country Status (27)

Country Link
US (3) US20130323247A1 (el)
EP (2) EP2342227B1 (el)
JP (2) JP5647132B2 (el)
KR (1) KR101695327B1 (el)
CN (2) CN102209728A (el)
AU (4) AU2009313040B2 (el)
BR (1) BRPI0921482B1 (el)
CA (1) CA2742249C (el)
CY (2) CY1117033T1 (el)
DK (2) DK2342227T3 (el)
ES (2) ES2558434T3 (el)
HK (2) HK1158668A1 (el)
HR (2) HRP20151168T1 (el)
HU (2) HUE028175T2 (el)
IL (1) IL212652A (el)
LT (1) LT2982696T (el)
ME (2) ME03480B (el)
MX (1) MX2011002927A (el)
NZ (1) NZ591311A (el)
PL (2) PL2982696T3 (el)
PT (2) PT2342227E (el)
RS (2) RS54456B1 (el)
RU (1) RU2536940C2 (el)
SI (2) SI2342227T1 (el)
SM (1) SMT201500328B (el)
WO (1) WO2010052014A1 (el)
ZA (1) ZA201103255B (el)

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WO2018026953A1 (en) 2016-08-02 2018-02-08 TCR2 Therapeutics Inc. Compositions and methods for tcr reprogramming using fusion proteins
JP7217970B2 (ja) 2016-10-07 2023-02-06 ティーシーアール２ セラピューティクス インク． 融合タンパク質を用いてｔ細胞受容体をリプログラミングするための組成物及び方法
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Also Published As

Publication number Publication date
WO2010052014A1 (en) 2010-05-14
HRP20151168T1 (hr) 2015-12-04
RU2536940C2 (ru) 2014-12-27
ES2558434T3 (es) 2016-02-04
SMT201500328B (it) 2016-02-25
AU2015238784A1 (en) 2015-10-29
LT2982696T (lt) 2019-06-10
US20190300609A1 (en) 2019-10-03
HK1158668A1 (en) 2012-07-20
ES2727585T3 (es) 2019-10-17
AU2018260815B2 (en) 2020-03-05
PL2982696T3 (pl) 2019-08-30
EP2982696B1 (en) 2019-03-27
RS58827B1 (sr) 2019-07-31
US11597766B2 (en) 2023-03-07
DK2342227T3 (en) 2016-02-15
CA2742249C (en) 2020-07-21
MX2011002927A (es) 2011-04-11
EP2982696A3 (en) 2016-02-17
HK1220705A1 (zh) 2017-05-12
ME02363B (me) 2016-06-20
US20240109964A1 (en) 2024-04-04
DK2982696T3 (da) 2019-05-27
JP5955921B2 (ja) 2016-07-20
CN102209728A (zh) 2011-10-05
EP2342227B1 (en) 2015-10-07
EP2982696A2 (en) 2016-02-10
IL212652A0 (en) 2011-07-31
PT2982696T (pt) 2019-06-04
CA2742249A1 (en) 2010-05-14
ZA201103255B (en) 2013-12-23
CY1117033T1 (el) 2017-04-05
PT2342227E (pt) 2015-11-13
CN107184977A (zh) 2017-09-22
BRPI0921482B1 (pt) 2022-09-20
AU2017219083A1 (en) 2017-09-14
BRPI0921482A2 (pt) 2016-01-12
AU2009313040A1 (en) 2010-05-14
HUE043326T2 (hu) 2019-08-28
SI2342227T1 (sl) 2015-12-31
AU2018260815A1 (en) 2018-11-22
RU2011122819A (ru) 2012-12-20
HUE028175T2 (en) 2016-12-28
JP2012508164A (ja) 2012-04-05
EP2342227A1 (en) 2011-07-13
KR20110091668A (ko) 2011-08-12
JP2015057417A (ja) 2015-03-26
RS54456B1 (en) 2016-06-30
BRPI0921482A8 (pt) 2017-07-11
US20130323247A1 (en) 2013-12-05
AU2009313040B2 (en) 2015-07-09
IL212652A (en) 2015-05-31
JP5647132B2 (ja) 2014-12-24
ME03480B (me) 2020-01-20
SI2982696T1 (sl) 2019-06-28
PL2342227T3 (pl) 2016-04-29
AU2017219083B2 (en) 2018-08-09
NZ591311A (en) 2012-10-26
HRP20190912T1 (hr) 2019-07-26
KR101695327B1 (ko) 2017-01-11

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