CY1118665T1 - Συνθεσεις και μεθοδοι για θεραπεια διαταραχων χρησης αλκοολης, πονου και αλλων ασθενειων - Google Patents

Συνθεσεις και μεθοδοι για θεραπεια διαταραχων χρησης αλκοολης, πονου και αλλων ασθενειων

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Publication number
CY1118665T1
CY1118665T1 CY20171100243T CY171100243T CY1118665T1 CY 1118665 T1 CY1118665 T1 CY 1118665T1 CY 20171100243 T CY20171100243 T CY 20171100243T CY 171100243 T CY171100243 T CY 171100243T CY 1118665 T1 CY1118665 T1 CY 1118665T1
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Cyprus
Prior art keywords
methods
compounds
diseases
pain
compositions
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CY20171100243T
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English (en)
Inventor
Jay Jie-Qiang Wu
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Vm Discovery, Inc.
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Publication date
Application filed by Vm Discovery, Inc. filed Critical Vm Discovery, Inc.
Publication of CY1118665T1 publication Critical patent/CY1118665T1/el

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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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Abstract

Η παρούσα εφεύρεση παρέχει ενώσεις οι οποίες ανταγωνίζονται κινάση C πρωτεΐνης έψιλον (ΡΚCε). Αυτές οι ενώσεις έχουν συντακτικό τύπο (la), (lc) ή (II). Η παρούσα εφεύρεση επίσης παρέχει φαρμακευτικές συνθέσεις που περιέχουν αυτές τις ενώσεις και μεθόδους θεραπείας διαφόρων ασθενειών, καταστάσεων ή/και συμπτωμάτων με χρήση αυτών των ενώσεων.
CY20171100243T 2008-10-10 2017-02-22 Συνθεσεις και μεθοδοι για θεραπεια διαταραχων χρησης αλκοολης, πονου και αλλων ασθενειων CY1118665T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10467208P 2008-10-10 2008-10-10
PCT/US2009/060367 WO2010042925A2 (en) 2008-10-10 2009-10-12 Compositions and methods for treating alcohol use disorders, pain and other diseases

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CY1118665T1 true CY1118665T1 (el) 2017-07-12

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PT3135672T (pt) 2020-04-02
CN102177153A (zh) 2011-09-07
PL2356109T3 (pl) 2017-07-31
CN106243100B (zh) 2019-04-09
HUE050319T2 (hu) 2020-11-30
EP3135672A1 (en) 2017-03-01
SI2356109T1 (sl) 2017-04-26
LT2356109T (lt) 2017-03-27
DK3135672T3 (da) 2020-05-04
CY1123625T1 (el) 2022-03-24
DK2356109T3 (en) 2017-03-13
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LT3135672T (lt) 2020-05-25
SI3135672T1 (sl) 2020-07-31
WO2010042925A3 (en) 2010-07-29
HRP20200552T1 (hr) 2020-07-10
EP2356109A4 (en) 2012-05-30
ES2617873T3 (es) 2017-06-20
CN106243100A (zh) 2016-12-21
WO2010042925A2 (en) 2010-04-15
CN102177153B (zh) 2016-09-21
EP3135672B1 (en) 2020-02-19
EP2356109B1 (en) 2016-12-07
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HRP20170357T1 (hr) 2017-05-05

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