CY1118665T1 - Συνθεσεις και μεθοδοι για θεραπεια διαταραχων χρησης αλκοολης, πονου και αλλων ασθενειων - Google Patents
Συνθεσεις και μεθοδοι για θεραπεια διαταραχων χρησης αλκοολης, πονου και αλλων ασθενειωνInfo
- Publication number
- CY1118665T1 CY1118665T1 CY20171100243T CY171100243T CY1118665T1 CY 1118665 T1 CY1118665 T1 CY 1118665T1 CY 20171100243 T CY20171100243 T CY 20171100243T CY 171100243 T CY171100243 T CY 171100243T CY 1118665 T1 CY1118665 T1 CY 1118665T1
- Authority
- CY
- Cyprus
- Prior art keywords
- methods
- compounds
- diseases
- pain
- compositions
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 102000003923 Protein Kinase C Human genes 0.000 abstract 1
- 108090000315 Protein Kinase C Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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Abstract
Η παρούσα εφεύρεση παρέχει ενώσεις οι οποίες ανταγωνίζονται κινάση C πρωτεΐνης έψιλον (ΡΚCε). Αυτές οι ενώσεις έχουν συντακτικό τύπο (la), (lc) ή (II). Η παρούσα εφεύρεση επίσης παρέχει φαρμακευτικές συνθέσεις που περιέχουν αυτές τις ενώσεις και μεθόδους θεραπείας διαφόρων ασθενειών, καταστάσεων ή/και συμπτωμάτων με χρήση αυτών των ενώσεων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10467208P | 2008-10-10 | 2008-10-10 | |
PCT/US2009/060367 WO2010042925A2 (en) | 2008-10-10 | 2009-10-12 | Compositions and methods for treating alcohol use disorders, pain and other diseases |
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PT (2) | PT3135672T (el) |
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WO2013043985A1 (en) | 2011-09-23 | 2013-03-28 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
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ES2782376T3 (es) | 2020-09-14 |
US8729081B2 (en) | 2014-05-20 |
PL3135672T3 (pl) | 2020-11-16 |
US20110301149A1 (en) | 2011-12-08 |
EP3135672B9 (en) | 2020-05-20 |
PT3135672T (pt) | 2020-04-02 |
CN102177153A (zh) | 2011-09-07 |
PL2356109T3 (pl) | 2017-07-31 |
CN106243100B (zh) | 2019-04-09 |
HUE050319T2 (hu) | 2020-11-30 |
EP3135672A1 (en) | 2017-03-01 |
SI2356109T1 (sl) | 2017-04-26 |
LT2356109T (lt) | 2017-03-27 |
DK3135672T3 (da) | 2020-05-04 |
CY1123625T1 (el) | 2022-03-24 |
DK2356109T3 (en) | 2017-03-13 |
HUE033711T2 (en) | 2017-12-28 |
LT3135672T (lt) | 2020-05-25 |
SI3135672T1 (sl) | 2020-07-31 |
WO2010042925A3 (en) | 2010-07-29 |
HRP20200552T1 (hr) | 2020-07-10 |
EP2356109A4 (en) | 2012-05-30 |
ES2617873T3 (es) | 2017-06-20 |
CN106243100A (zh) | 2016-12-21 |
WO2010042925A2 (en) | 2010-04-15 |
CN102177153B (zh) | 2016-09-21 |
EP3135672B1 (en) | 2020-02-19 |
EP2356109B1 (en) | 2016-12-07 |
PT2356109T (pt) | 2017-03-10 |
EP2356109A2 (en) | 2011-08-17 |
HRP20170357T1 (hr) | 2017-05-05 |
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