CY1110965T1 - Επιπροσθετες ετεροπολυκυκλικες ενωσεις και η χρηση τους ως ανταγωνιστες μεταβολοτροπικου υποδοχεα γλουταμικου - Google Patents

Επιπροσθετες ετεροπολυκυκλικες ενωσεις και η χρηση τους ως ανταγωνιστες μεταβολοτροπικου υποδοχεα γλουταμικου

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Publication number
CY1110965T1
CY1110965T1 CY20101101116T CY101101116T CY1110965T1 CY 1110965 T1 CY1110965 T1 CY 1110965T1 CY 20101101116 T CY20101101116 T CY 20101101116T CY 101101116 T CY101101116 T CY 101101116T CY 1110965 T1 CY1110965 T1 CY 1110965T1
Authority
CY
Cyprus
Prior art keywords
compounds
hyperpyrocyclic
glutamic
additional
prevention
Prior art date
Application number
CY20101101116T
Other languages
English (en)
Inventor
Louise Edwards
Methvin Isaac
Martin Johansson
Annika Kers
Johan Malmberg
Donald Mcleod
Alexander Minidis
Karin Staaf
Abdelmalik Slassi
Tomislav Stefanac
Thomas Stormann
David Wensbo
Tao Xin
Jalaj Arora
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CY1110965T1 publication Critical patent/CY1110965T1/el

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

Η παρούσα εφεύρεση αφορά νέες ενώσεις του τύπου (I), φαρμακευτικές συνταγοποιήσεις που περιέχουν τις ενώσεις, και την χρήση των ενώσεων στην πρόληψη ή/και θεραπεία διαταραχών που διαμεσολαβούνται από τον υποδοχέα mGluR5.
CY20101101116T 2004-02-18 2010-12-03 Επιπροσθετες ετεροπολυκυκλικες ενωσεις και η χρηση τους ως ανταγωνιστες μεταβολοτροπικου υποδοχεα γλουταμικου CY1110965T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60896004P 2004-02-18 2004-02-18
EP05802855A EP1723144B1 (en) 2004-02-18 2005-02-15 Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists

Publications (1)

Publication Number Publication Date
CY1110965T1 true CY1110965T1 (el) 2015-06-11

Family

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Family Applications (1)

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CY20101101116T CY1110965T1 (el) 2004-02-18 2010-12-03 Επιπροσθετες ετεροπολυκυκλικες ενωσεις και η χρηση τους ως ανταγωνιστες μεταβολοτροπικου υποδοχεα γλουταμικου

Country Status (27)

Country Link
US (6) US7585881B2 (el)
EP (2) EP1723144B1 (el)
JP (1) JP4912157B2 (el)
CN (2) CN101096368A (el)
AT (1) ATE483706T1 (el)
AU (1) AU2005270208A1 (el)
BR (1) BRPI0507497A (el)
CA (1) CA2555566A1 (el)
CY (1) CY1110965T1 (el)
DE (1) DE602005023963D1 (el)
DK (1) DK1723144T3 (el)
ES (1) ES2352110T3 (el)
HK (1) HK1099285A1 (el)
HR (1) HRP20100654T1 (el)
IL (1) IL177394A0 (el)
NO (1) NO20063599L (el)
NZ (1) NZ548954A (el)
PL (1) PL1723144T3 (el)
PT (1) PT1723144E (el)
RS (1) RS51516B (el)
RU (1) RU2370495C2 (el)
SG (1) SG146657A1 (el)
SI (1) SI1723144T1 (el)
UA (1) UA84318C2 (el)
UY (1) UY28766A1 (el)
WO (1) WO2006014185A1 (el)
ZA (1) ZA200606551B (el)

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