AR073268A1 - Forma cristalina de 4-(5-[(1r)-1-[5-(3-clorofenil)isoxazol-3-il] etoxi]-4-metil-4h-1,2,4-triazol-3-il)piridina. - Google Patents
Forma cristalina de 4-(5-[(1r)-1-[5-(3-clorofenil)isoxazol-3-il] etoxi]-4-metil-4h-1,2,4-triazol-3-il)piridina.Info
- Publication number
- AR073268A1 AR073268A1 ARP090103084A ARP090103084A AR073268A1 AR 073268 A1 AR073268 A1 AR 073268A1 AR P090103084 A ARP090103084 A AR P090103084A AR P090103084 A ARP090103084 A AR P090103084A AR 073268 A1 AR073268 A1 AR 073268A1
- Authority
- AR
- Argentina
- Prior art keywords
- isoxazol
- triazol
- chlorophenyl
- pyridine
- methyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
Abstract
La presente se refiere a una nueva forma cristalina de 4-(5-{(1R)-1-[5-(3-clorofenil)isoxazol-3-il]etoxi} -4-metil-4H-1,2,4-triazol-3-il)piridina. Además, la presente también se refiere al uso de una nueva forma cristalina para el tratamiento de trastornos digestivos, a composiciones farmacéuticas que la contienen así como a procesos para la preparacion de la nueva forma cristalina. Reivindicacion 2: La 4-(5-{(1R)-1-[5-(3-clorofenil)isoxazol-3-il]etoxi} -4-metil-4H-1,2,4-triazol-3-il)piridina en forma cristalina de acuerdo con la reivindicacion 1, caracterizada por tener un patron de difraccion de rayos X en polvo que presenta básicamente el siguiente pico principal con valores d: en el cuadro de valores 1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8805308P | 2008-08-12 | 2008-08-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR073268A1 true AR073268A1 (es) | 2010-10-28 |
Family
ID=41669086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090103084A AR073268A1 (es) | 2008-08-12 | 2009-08-11 | Forma cristalina de 4-(5-[(1r)-1-[5-(3-clorofenil)isoxazol-3-il] etoxi]-4-metil-4h-1,2,4-triazol-3-il)piridina. |
Country Status (15)
Country | Link |
---|---|
US (1) | US20100041706A1 (es) |
EP (1) | EP2324019A4 (es) |
JP (1) | JP2011530590A (es) |
KR (1) | KR20110040910A (es) |
CN (1) | CN102177158A (es) |
AR (1) | AR073268A1 (es) |
AU (1) | AU2009282523A1 (es) |
BR (1) | BRPI0917465A2 (es) |
CA (1) | CA2733922A1 (es) |
IL (1) | IL210923A0 (es) |
MX (1) | MX2011001549A (es) |
RU (1) | RU2011103224A (es) |
TW (1) | TW201011016A (es) |
UY (1) | UY32043A (es) |
WO (1) | WO2010019101A1 (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
US7585881B2 (en) * | 2004-02-18 | 2009-09-08 | Astrazeneca Ab | Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
UY29796A1 (es) * | 2005-09-29 | 2007-04-30 | Astrazeneca Ab | Nuevos compuestos para el tratamiento de trastornos neurológicos, psiquiátricos o del dolor |
WO2007043939A1 (en) * | 2005-10-07 | 2007-04-19 | Astrazeneca Ab | Novel crystalline form of 3,5-dibromo-n- [(2s)-2-(-4-fluorophenyl)-4-(3-morpholin-4-ylazetidin-1-yl)butyl] -n-methylbenzamide, modification a |
TW200821305A (en) * | 2006-10-05 | 2008-05-16 | Astrazeneca Ab | MGluR5 modulators |
-
2009
- 2009-08-11 AR ARP090103084A patent/AR073268A1/es unknown
- 2009-08-11 BR BRPI0917465A patent/BRPI0917465A2/pt not_active IP Right Cessation
- 2009-08-11 RU RU2011103224/04A patent/RU2011103224A/ru not_active Application Discontinuation
- 2009-08-11 EP EP09806923A patent/EP2324019A4/en not_active Withdrawn
- 2009-08-11 MX MX2011001549A patent/MX2011001549A/es not_active Application Discontinuation
- 2009-08-11 WO PCT/SE2009/050928 patent/WO2010019101A1/en active Application Filing
- 2009-08-11 CA CA2733922A patent/CA2733922A1/en not_active Abandoned
- 2009-08-11 AU AU2009282523A patent/AU2009282523A1/en not_active Abandoned
- 2009-08-11 JP JP2011522938A patent/JP2011530590A/ja active Pending
- 2009-08-11 US US12/539,082 patent/US20100041706A1/en not_active Abandoned
- 2009-08-11 CN CN2009801403204A patent/CN102177158A/zh active Pending
- 2009-08-11 KR KR1020117003215A patent/KR20110040910A/ko not_active Application Discontinuation
- 2009-08-11 UY UY0001032043A patent/UY32043A/es not_active Application Discontinuation
- 2009-08-11 TW TW098126983A patent/TW201011016A/zh unknown
-
2011
- 2011-01-27 IL IL210923A patent/IL210923A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20110040910A (ko) | 2011-04-20 |
IL210923A0 (en) | 2011-04-28 |
MX2011001549A (es) | 2011-03-15 |
TW201011016A (en) | 2010-03-16 |
US20100041706A1 (en) | 2010-02-18 |
EP2324019A1 (en) | 2011-05-25 |
CA2733922A1 (en) | 2010-02-18 |
EP2324019A4 (en) | 2011-10-05 |
WO2010019101A1 (en) | 2010-02-18 |
JP2011530590A (ja) | 2011-12-22 |
CN102177158A (zh) | 2011-09-07 |
BRPI0917465A2 (pt) | 2017-04-04 |
UY32043A (es) | 2010-03-26 |
RU2011103224A (ru) | 2012-09-20 |
AU2009282523A1 (en) | 2010-02-18 |
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