WO2012090043A8 - Novel solid state forms of azilsartan medoxomil and preparation thereof - Google Patents

Novel solid state forms of azilsartan medoxomil and preparation thereof Download PDF

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Publication number
WO2012090043A8
WO2012090043A8 PCT/IB2011/003055 IB2011003055W WO2012090043A8 WO 2012090043 A8 WO2012090043 A8 WO 2012090043A8 IB 2011003055 W IB2011003055 W IB 2011003055W WO 2012090043 A8 WO2012090043 A8 WO 2012090043A8
Authority
WO
WIPO (PCT)
Prior art keywords
solid state
preparation
azilsartan medoxomil
state forms
novel solid
Prior art date
Application number
PCT/IB2011/003055
Other languages
French (fr)
Other versions
WO2012090043A1 (en
Inventor
Himanchal MISHRA
Deepak Bansal
Muni Bhaskar PALLOORU
Alka Srivastava CHOUDHARY
Dharam Vir
Ashutosh Agarwal
Shailendr Kumar DUBEY
Original Assignee
Jubilant Life Sciences Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jubilant Life Sciences Limited filed Critical Jubilant Life Sciences Limited
Publication of WO2012090043A1 publication Critical patent/WO2012090043A1/en
Publication of WO2012090043A8 publication Critical patent/WO2012090043A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention provides novel solid state forms of azilsartan medoxomil and process for the preparation thereof. The solid state forms of the present invention includes crystalline forms viz. J2, J3, J4, J5, J6, J7, J8, J9 and amorphous forms of azilsartan medoxomil. Further, it relates to the pharmaceutical composition and use of the said formulation to treat the conditions in a subject in need thereof.
PCT/IB2011/003055 2010-12-29 2011-12-16 Novel solid state forms of azilsartan medoxomil and preparation thereof WO2012090043A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN3155DE2010 2010-12-29
IN3155/DEL/2010 2010-12-29
IN316DE2011 2011-02-08
IN316/DEL/2011 2011-02-08

Publications (2)

Publication Number Publication Date
WO2012090043A1 WO2012090043A1 (en) 2012-07-05
WO2012090043A8 true WO2012090043A8 (en) 2012-09-13

Family

ID=45540893

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2011/003055 WO2012090043A1 (en) 2010-12-29 2011-12-16 Novel solid state forms of azilsartan medoxomil and preparation thereof

Country Status (1)

Country Link
WO (1) WO2012090043A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102323280A (en) * 2011-05-11 2012-01-18 浙江长生鸟珍珠生物科技有限公司 Quality detection methods of pearl powder and application thereof
WO2013042066A1 (en) * 2011-09-20 2013-03-28 Ranbaxy Laboratories Limited Process for the preparation of azilsartan medoxomil
US9403811B2 (en) 2012-01-14 2016-08-02 Sunshine Lake Pharma Co., Ltd. Crystalline forms of azilsartan medoxomil potassium and preparation and uses thereof
WO2013124748A1 (en) * 2012-02-20 2013-08-29 Alembic Pharmaceuticals Limited Novel polymorphs of azilsartan medoxomil potassium
CZ2012274A3 (en) * 2012-04-19 2013-10-30 Zentiva, K.S. Process for preparing extremely pure potassium salt of azilsartan medoxomil
WO2013186792A2 (en) * 2012-06-11 2013-12-19 Msn Laboratories Limited Process for the preparation of (5-methyl-2-oxo-l,3-dioxoi-4-vl)methvl 2- ethoxv-l-{[2'-(5-oxo-4,5-dihvdro-l,2,4-oxadiazol-3-vl)biphenyi-4-vl]methyl}- lh-benzimidazole-7-carboxyiate and its salts
EP2870151A4 (en) * 2012-07-09 2016-03-23 Hetero Research Foundation Novel polymorphs of azilsartan
WO2014020381A1 (en) * 2012-08-01 2014-02-06 Alembic Pharmaceuticals Limited Novel crystalline form of azilsartan medoxomil potassium
CA2890961A1 (en) * 2012-08-27 2014-03-06 Hetero Research Foundation Novel polymorphs of azilsartan medoxomil
WO2014049512A2 (en) 2012-09-26 2014-04-03 Lupin Limited Novel process for preparation of azilsartan medoxomil
CZ305318B6 (en) * 2012-09-26 2015-07-29 Zentiva, K.S. Process for preparing extremely pure azilsartan medoxomil potassium salt
CN103709154B (en) * 2012-09-28 2016-06-15 武汉朗来科技发展有限公司 Benzimidizole derivatives and preparation method thereof and medical usage
CN103880829B (en) * 2012-12-21 2016-07-06 上海医药工业研究院 A kind of Azilsartan crystal and its production and use
CN103910720A (en) * 2013-01-07 2014-07-09 广东东阳光药业有限公司 Novel crystal form of azilsartan medoxomil and preparation method thereof
CN105153141B (en) * 2013-02-04 2018-09-25 武汉朗来科技发展有限公司 Benzimidizole derivatives and preparation method thereof and medical usage
CN104774196B (en) * 2014-01-09 2017-11-10 武汉朗来科技发展有限公司 A kind of preparation method of benzimidizole derivatives
CN104557899B (en) * 2014-11-17 2018-05-22 江苏中邦制药有限公司 A kind of preparation method of Azilsartan I crystal crystal
WO2016145622A1 (en) 2015-03-18 2016-09-22 武汉朗来科技发展有限公司 Benzimidazole derivatives, preparation method therefor and medicinal use thereof
CN106032378B (en) * 2015-03-20 2019-10-25 武汉启瑞药业有限公司 New A RB compound and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7157584B2 (en) * 2004-02-25 2007-01-02 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof

Also Published As

Publication number Publication date
WO2012090043A1 (en) 2012-07-05

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