WO2013088384A3 - Solid state forms of azilsartan and azilsartan medoxomil monopotassium and preparation thereof - Google Patents

Solid state forms of azilsartan and azilsartan medoxomil monopotassium and preparation thereof Download PDF

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Publication number
WO2013088384A3
WO2013088384A3 PCT/IB2012/057265 IB2012057265W WO2013088384A3 WO 2013088384 A3 WO2013088384 A3 WO 2013088384A3 IB 2012057265 W IB2012057265 W IB 2012057265W WO 2013088384 A3 WO2013088384 A3 WO 2013088384A3
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WO
WIPO (PCT)
Prior art keywords
azilsartan
medoxomil
preparation
monopotassium
solid state
Prior art date
Application number
PCT/IB2012/057265
Other languages
French (fr)
Other versions
WO2013088384A2 (en
Inventor
Shailendr Kumar DUBEY
Himanchal MISHRA
Deepak Bansal
Alka Srivastava CHOUDHARY
Dharam Vir
Ashutosh Agarwal
Original Assignee
Jubilant Life Sciences Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jubilant Life Sciences Limited filed Critical Jubilant Life Sciences Limited
Publication of WO2013088384A2 publication Critical patent/WO2013088384A2/en
Publication of WO2013088384A3 publication Critical patent/WO2013088384A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to novel solid state forms of azilsartan and azilsartan medoxomil monopotassium salt i.e. amorphous and crystalline forms of azilsartan and azilsartan medoxomil monopotassium salt and processes for the preparation thereof. The present invention also relates to co-precipitate of azilsartan. Further, it relates to the pharmaceutical composition of amorphous and crystalline forms of azilsartan and azilsartan medoxomil monopotassium salt and its use.
PCT/IB2012/057265 2011-12-15 2012-12-13 Solid state forms of azilsartan and azilsartan medoxomil monopotassium and preparation thereof WO2013088384A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN3661DE2011 2011-12-15
IN3661/DEL/2011 2011-12-15
IN2183/DEL/2012 2012-07-13
IN2183DE2012 2012-07-13

Publications (2)

Publication Number Publication Date
WO2013088384A2 WO2013088384A2 (en) 2013-06-20
WO2013088384A3 true WO2013088384A3 (en) 2013-11-07

Family

ID=47678901

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/057265 WO2013088384A2 (en) 2011-12-15 2012-12-13 Solid state forms of azilsartan and azilsartan medoxomil monopotassium and preparation thereof

Country Status (1)

Country Link
WO (1) WO2013088384A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104039779B (en) 2012-01-14 2016-08-24 广东东阳光药业有限公司 Crystal formation of Azilsartan potassium and preparation method thereof and application thereof
CN104341408A (en) * 2013-08-02 2015-02-11 江苏柯菲平医药股份有限公司 Novel crystal form of azilsartan and preparation method thereof
CZ2014702A3 (en) 2014-10-15 2016-04-27 Zentiva, K.S. Process for preparing extremely pure azilsartan
CN108358904A (en) * 2018-03-28 2018-08-03 梧州学院 A kind of eutectic and preparation method thereof of Azilsartan and 4,4 '-bipyridyls

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0520423A2 (en) * 1991-06-27 1992-12-30 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use as angiotensin II antagonists
US7157584B2 (en) * 2004-02-25 2007-01-02 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0520423A2 (en) * 1991-06-27 1992-12-30 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use as angiotensin II antagonists
US7157584B2 (en) * 2004-02-25 2007-01-02 Takeda Pharmaceutical Company Limited Benzimidazole derivative and use thereof

Also Published As

Publication number Publication date
WO2013088384A2 (en) 2013-06-20

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