WO2012107890A3 - Crystal forms of lurasidone chlorhydrate - Google Patents

Crystal forms of lurasidone chlorhydrate Download PDF

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Publication number
WO2012107890A3
WO2012107890A3 PCT/IB2012/050573 IB2012050573W WO2012107890A3 WO 2012107890 A3 WO2012107890 A3 WO 2012107890A3 IB 2012050573 W IB2012050573 W IB 2012050573W WO 2012107890 A3 WO2012107890 A3 WO 2012107890A3
Authority
WO
WIPO (PCT)
Prior art keywords
lurasidone
chlorhydrate
crystal forms
schizophrenia
processes
Prior art date
Application number
PCT/IB2012/050573
Other languages
French (fr)
Other versions
WO2012107890A2 (en
Inventor
Suresh Babu Jayachandra
Tarun Kumar SINGH
Udaibhan Singh GAHLOT
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Publication of WO2012107890A2 publication Critical patent/WO2012107890A2/en
Publication of WO2012107890A3 publication Critical patent/WO2012107890A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides crystalline forms of lurasidone hydrochloride, processes for their preparation, pharmaceutical compositions comprising them and their use for the treatment of schizophrenia.
PCT/IB2012/050573 2011-02-10 2012-02-08 Crystalline forms of lurasidone hydrochloride WO2012107890A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN340DE2011 2011-02-10
IN340/DEL/2011 2011-02-10

Publications (2)

Publication Number Publication Date
WO2012107890A2 WO2012107890A2 (en) 2012-08-16
WO2012107890A3 true WO2012107890A3 (en) 2012-11-01

Family

ID=46639005

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/050573 WO2012107890A2 (en) 2011-02-10 2012-02-08 Crystalline forms of lurasidone hydrochloride

Country Status (1)

Country Link
WO (1) WO2012107890A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013030722A1 (en) * 2011-08-26 2013-03-07 Ranbaxy Laboratories Limited Crystalline lurasidone hydrochloride
WO2013121440A1 (en) 2012-02-13 2013-08-22 Cadila Healthcare Limited Process for preparing benzisothiazol-3-yl-peperazin-l-yl-methyl-cyclo hexyl-methanisoindol-1,3-dione and its intermediates
CN102863437A (en) * 2012-09-04 2013-01-09 济南百诺医药科技开发有限公司 Preparation method of lurasidone
WO2014064714A2 (en) * 2012-10-22 2014-05-01 Glenmark Pharmaceuticals Limited; Glenmark Generics Limited Process for preparation of lurasidone hydrochloride
CN102911170A (en) * 2012-11-15 2013-02-06 苏州第壹制药有限公司 Method for preparing imide compound hydrochloride
WO2014102834A2 (en) * 2012-12-31 2014-07-03 Hetero Research Foundation Process for lurasidone
CN105524057A (en) * 2013-03-06 2016-04-27 江苏恩华药业股份有限公司 Lurasidone hydrochloride new crystal form and preparation method thereof
SI3154967T1 (en) 2014-06-16 2020-11-30 Johnson Matthey Public Limited Company, Processes for making alkylated arylpiperazine and alkylated arylpiperidine compounds including novel intermediates
US10987303B2 (en) 2018-05-02 2021-04-27 LifeMax Laboratories, Inc. Extended release suspension formulation of lurasidone

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0464846A1 (en) * 1990-07-06 1992-01-08 Sumitomo Pharmaceuticals Company, Limited Imide derivatives, and their production and use
EP1327440A1 (en) * 2000-09-22 2003-07-16 Sumitomo Pharmaceuticals Company, Limited Oral preparations with favorable disintegration characteristics
EP1652848A1 (en) * 2003-07-29 2006-05-03 Dainippon Sumitomo Pharma Co., Ltd. Process for producing imide compound
EP1884242A1 (en) * 2005-05-26 2008-02-06 Dainippon Sumitomo Pharma Co., Ltd. Pharmaceutical composition
EP1891956A1 (en) * 2005-06-13 2008-02-27 Dainippon Sumitomo Pharma Co., Ltd. Solubilization preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0464846A1 (en) * 1990-07-06 1992-01-08 Sumitomo Pharmaceuticals Company, Limited Imide derivatives, and their production and use
EP1327440A1 (en) * 2000-09-22 2003-07-16 Sumitomo Pharmaceuticals Company, Limited Oral preparations with favorable disintegration characteristics
EP1652848A1 (en) * 2003-07-29 2006-05-03 Dainippon Sumitomo Pharma Co., Ltd. Process for producing imide compound
EP1884242A1 (en) * 2005-05-26 2008-02-06 Dainippon Sumitomo Pharma Co., Ltd. Pharmaceutical composition
EP1891956A1 (en) * 2005-06-13 2008-02-27 Dainippon Sumitomo Pharma Co., Ltd. Solubilization preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
COLE, P. ET AL: "Lurasidone hydrochloride : dopamine D2/5-HT2A antagonist treatment of schizophrenia", DRUGS OF THE FUTURE, vol. 33, no. 4, 2008, pages 316 - 322, XP002681381 *

Also Published As

Publication number Publication date
WO2012107890A2 (en) 2012-08-16

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