WO2011095985A3 - Rasagiline salts and processes for the preparation thereof - Google Patents

Rasagiline salts and processes for the preparation thereof Download PDF

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Publication number
WO2011095985A3
WO2011095985A3 PCT/IN2011/000059 IN2011000059W WO2011095985A3 WO 2011095985 A3 WO2011095985 A3 WO 2011095985A3 IN 2011000059 W IN2011000059 W IN 2011000059W WO 2011095985 A3 WO2011095985 A3 WO 2011095985A3
Authority
WO
WIPO (PCT)
Prior art keywords
processes
preparation
rasagiline salts
rasagiline
salts
Prior art date
Application number
PCT/IN2011/000059
Other languages
French (fr)
Other versions
WO2011095985A2 (en
Inventor
Sunil Sudhakar Zope
Colony Deshmukh
Laxmikant Madhukar Kelkar
Joseph Prabahar Koilpillai
Milind Moreshwar Gharpure
Original Assignee
Glenmark Generics Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Limited filed Critical Glenmark Generics Limited
Publication of WO2011095985A2 publication Critical patent/WO2011095985A2/en
Publication of WO2011095985A3 publication Critical patent/WO2011095985A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to crystalline salts of rasagiline and processes for the preparation thereof. The invention also relates to pharmaceutical compositions comprising the same.
PCT/IN2011/000059 2010-02-02 2011-01-28 Rasagiline salts and processes for the preparation thereof WO2011095985A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN242MU2010 2010-02-02
IN242/MUM/2010 2010-02-02

Publications (2)

Publication Number Publication Date
WO2011095985A2 WO2011095985A2 (en) 2011-08-11
WO2011095985A3 true WO2011095985A3 (en) 2011-12-22

Family

ID=44355887

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2011/000059 WO2011095985A2 (en) 2010-02-02 2011-01-28 Rasagiline salts and processes for the preparation thereof

Country Status (1)

Country Link
WO (1) WO2011095985A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU231054B1 (en) * 2010-11-18 2020-04-28 Egis Gyógyszergyár Nyrt. Novel salts suitable for the preparation of pharmaceutical compositions
EP2705021A2 (en) 2011-05-04 2014-03-12 Cadila Healthcare Limited Rasagiline and its pharmaceutically acceptable salts
DE102012000786A1 (en) 2012-01-18 2013-07-18 Stada Arzneimittel Ag Process for the preparation of a solid pharmaceutical composition containing the active substance rasagiline
CN111983075A (en) * 2020-08-17 2020-11-24 重庆华森制药股份有限公司 Method for detecting rasagiline and enantiomer thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532415A (en) * 1990-01-03 1996-07-02 Teva Pharmaceutical Industries Ltd. R-enantiomer of N-propargyl-1-aminoindan, salts, compositions and uses thereof
US6959060B2 (en) * 2000-08-31 2005-10-25 Lg Electronics Inc. Jitter reducing apparatus using digital modulation technique
CN1911211A (en) * 2006-08-25 2007-02-14 重庆医药工业研究院有限责任公司 Solid oral prepn. of leishajilan
CN101600346A (en) * 2006-12-14 2009-12-09 泰华制药工业有限公司 The tannate of Rasagiline

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532415A (en) * 1990-01-03 1996-07-02 Teva Pharmaceutical Industries Ltd. R-enantiomer of N-propargyl-1-aminoindan, salts, compositions and uses thereof
US6959060B2 (en) * 2000-08-31 2005-10-25 Lg Electronics Inc. Jitter reducing apparatus using digital modulation technique
CN1911211A (en) * 2006-08-25 2007-02-14 重庆医药工业研究院有限责任公司 Solid oral prepn. of leishajilan
CN101600346A (en) * 2006-12-14 2009-12-09 泰华制药工业有限公司 The tannate of Rasagiline

Also Published As

Publication number Publication date
WO2011095985A2 (en) 2011-08-11

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